Diagnosis

If your doctor suspects a molar pregnancy, he or she will probably order a blood test to measure the level of human chorionic gonadotropin (HCG) — a pregnancy hormone — in your blood. He or she will also likely do an ultrasound.

With a standard ultrasound, high-frequency sound waves are directed at the tissues in the abdominal and pelvic area. During early pregnancy, however, the uterus and fallopian tubes are closer to the vagina than to the abdominal surface, so the ultrasound may be done through a wandlike device placed in your vagina.

An ultrasound of a complete molar pregnancy — which can be detected as early as eight or nine weeks of pregnancy — may show:

  • No embryo or fetus
  • No amniotic fluid
  • A thick cystic placenta nearly filling the uterus
  • Ovarian cysts

An ultrasound of a partial molar pregnancy may show:

  • A growth-restricted fetus
  • Low amniotic fluid
  • A thick cystic placenta

If your health care provider detects a molar pregnancy, he or she may check for other medical problems, including:

  • Preeclampsia
  • Hyperthyroidism
  • Anemia

Treatment

A molar pregnancy can't continue as a normal viable pregnancy. To prevent complications, the molar tissue must be removed. Treatment usually consists of one or more of the following:

  • Dilation and curettage (D&C). To treat a molar pregnancy, your doctor removes the molar tissue from your uterus during a procedure called dilation and curettage (D&C). A D&C is usually done as an outpatient procedure in a hospital.

    During the procedure, you receive a local or general anesthetic and lie on your back with your legs in stirrups. Your doctor inserts a speculum into your vagina, as in a pelvic exam, to see your cervix. Your doctor then dilates your cervix and removes uterine tissue with a vacuum device. A D&C usually takes about 15 to 30 minutes.

  • Hysterectomy. If the molar tissue is extensive and there's no desire for future pregnancies, you might have surgery to remove your uterus (hysterectomy).
  • HCG monitoring. After the molar tissue is removed, your doctor repeats measurements of your HCG level until it returns to normal. If you continue to have HCG in your blood, you may need additional treatment. Once treatment for the molar pregnancy is complete, your doctor may continue to monitor your HCG levels for six months to one year to make sure there's no remaining molar tissue. Because pregnancy makes it difficult to monitor HCG levels, your doctor may recommend waiting until after follow-up before trying to become pregnant again.

Coping and support

Losing a pregnancy is devastating. Give yourself time to grieve. Talk about your feelings and allow yourself to experience them fully. Turn to your partner, family and friends for support. If you're having trouble handling your emotions, consult your pregnancy care provider or a counselor.

Preparing for your appointment

You're likely to start by talking with your family doctor or pregnancy care provider. Here's some information to help you get ready for your appointment and know what to expect from your doctor.

What you can do

Before your appointment:

  • Write down any symptoms you're experiencing, including when they first started and how they've changed over time.
  • Make note of the date of your last menstrual period, if you remember it.
  • Write down key personal information, including any other medical conditions for which you're being treated.
  • Make a list of all medications, as well as any vitamins or supplements you're taking.
  • Ask a friend or family member to accompany you, if possible, to your appointment. Having someone else there may help you remember something that you forgot or missed and may provide much-needed emotional support.
  • Write down questions to ask your doctor.

Preparing a list of questions in advance will help you make the most of your time with your doctor. For molar pregnancy, some basic questions to ask include:

  • What is likely causing my symptoms or condition?
  • What kind of tests do I need?
  • What needs to be done now?
  • What treatment approach do you recommend?
  • Do I need to follow any restrictions?
  • What emergency signs and symptoms should I watch for at home?
  • What are my chances for a successful future pregnancy?
  • How long should I wait before trying to become pregnant again?
  • Does my condition increase my risk of developing cancer in the future?
  • Do you have any brochures or printed material that I can take with me? What websites do you recommend for more information?

In addition to the questions that you've prepared to ask your doctor, don't hesitate to ask questions during your appointment if you don't understand something.

What to expect from your doctor

Your doctor will likely perform a physical exam and run some tests, including a blood test and ultrasound exam. He or she also may ask you a number of questions, such as:

  • When was your last menstrual period?
  • When did you first begin experiencing symptoms?
  • Have your symptoms been continuous or occasional?
  • Are you having any pain?
  • Compared with your heaviest days of menstrual flow, is your bleeding more, less or about the same? Have you passed any grape-like cysts from your vagina?
  • Are you experiencing any lightheadedness or dizziness?
  • Have you had a past molar pregnancy?
  • What chronic conditions, if any, do you have?
  • Do you wish to become pregnant in the future?
Oct. 24, 2014
References
  1. Gestational trophoblastic disease. American Cancer Society. http://www.cancer.org/acs/groups/cid/documents/webcontent/003104-pdf.pdf. Accessed July 20, 2014.
  2. Molar pregnancy. March of Dimes. http://www.marchofdimes.com/loss/molar-pregnancy.aspx. Accessed July 19, 2014.
  3. Ferri FF. Ferri's Clinical Advisor 2015: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2015. https://www.clinicalkey.com. Accessed July 19, 2014.
  4. Goff B. Gestational trophoblastic disease: Management of hydatidiform mole. http://www.uptodate.com/home. Accessed July 19, 2014.
  5. Baergen RN. Gestational trophoblastic disease: Pathology. http://www.uptodate.com/home. Accessed July 19, 2014.
  6. Goldstein DP, et al. Gestational trophoblastic disease: Epidemiology, clinical manifestations and diagnosis. http://www.uptodate.com/home. Accessed July 19, 2014.
  7. Garner EIO. Gestational trophoblastic neoplasia: Staging and treatment. http://www.uptodate.com/home. Accessed July 19, 2014.
  8. Lentz GM, et al. Comprehensive Gynecology. 6th ed. Philadelphia, Pa.: Mosby Elsevier; 2012. http://www.clinicalkey.com. Accessed July 19, 2014.
  9. Frequently asked questions. Special procedures FAQ062. Dilation and curettage. American College of Obstetricians and Gynecologists. http://www.acog.org/publications/faq/faq062.cfm. Accessed July 19, 2014.
  10. American College of Obstetricians and Gynecologists (ACOG) Committee on Practice Bulletins — Obstetrics. ACOG Practice Bulletin No. 53: Diagnosis and treatment of gestational trophoblastic disease. Obstetrics & Gynecology. 2004;103:1365.
  11. Harms RW (expert opinion). Mayo Clinic, Rochester, Minn. Aug. 6, 2014.