Hypoplastic left heart syndrome

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Doctors who treat this condition

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Displaying 1-5 out of 5 doctors available

  1. Jason H. Anderson, M.D.

    Jason H. Anderson, M.D.

    1. Interventional Cardiologist
    2. Echocardiographer
    3. Pediatric Cardiologist
    1. Rochester, MN
    Areas of focus:

    Congenital heart defects in children, Congenital heart defects in adults, Patent ductus arteriosus, Coarctation of the ...aorta, Congenital heart defects in neonates and infants, Cardiomyopathy, Atrial septal defect, Ventricular septal defect, Hypoplastic left heart syndrome, Patent foramen ovale

  2. Adam Cassidy, Ph.D., L.P.

    Adam Cassidy, Ph.D., L.P.

    1. Neuropsychologist
    1. Rochester, MN
    Areas of focus:

    Neuropsychological assessment, Heart transplant complication, Transposition of the great arteries, Hypoplastic left hea...rt syndrome, Congenital heart disease, Tetralogy of Fallot, Ventricular septal defect, Atrial septal defect

  3. David S. Majdalany, M.D.

    David S. Majdalany, M.D.

    1. Cardiologist
    1. Phoenix, AZ
    Areas of focus:

    Stress echocardiogram, Echocardiogram, Transesophageal echocardiogram, Partial anomalous pulmonary venous return, Pulmo...nary atresia, Atrial septal defect, Pulmonary valve stenosis, Total anomalous pulmonary venous return, Transposition of the great arteries, Tricuspid atresia, Pulmonary atresia with ventricular septum defect, Ebstein anomaly, Tricuspid valve disease, Truncus arteriosus, Heart disease in pregnancy, Hypoplastic left heart syndrome, Bicuspid aortic valve, Marfan syndrome, Eisenmenger syndrome, Congenital heart defects in adults, Patent ductus arteriosus, Ventricular septal defect, Coarctation of the aorta, Congenital mitral valve anomaly, Patent foramen ovale, Aortic aneurysm, Vascular ring, Pulmonary atresia with intact ventricular septum, Double-outlet right ventricle, Tetralogy of Fallot, Atrioventricular canal defect

  4. Francois Marcotte, M.D.

    Francois Marcotte, M.D.

    1. Cardiologist
    1. Phoenix, AZ
    Areas of focus:

    Truncus arteriosus, Atrial septal defect, Ebstein anomaly, Coarctation of the aorta, Patent foramen ovale, Pulmonary at...resia, Ventricular septal defect, Partial anomalous pulmonary venous return, Double-outlet right ventricle, Tetralogy of Fallot, Patent ductus arteriosus, Bicuspid aortic valve, Pulmonary atresia with ventricular septum defect, Pulmonary valve stenosis, Congenital mitral valve anomaly, Total anomalous pulmonary venous return, Vascular ring, Hypoplastic left heart syndrome, Atrioventricular canal defect, Heart disease in pregnancy, Pulmonary atresia with intact ventricular septum, Tricuspid valve disease, Congenital heart defects in adults, Tricuspid atresia, Eisenmenger syndrome, Transposition of the great arteries

  5. Patrick W. O'Leary, M.D.

    Patrick W. O'Leary, M.D.

    1. Pediatric Cardiologist
    1. Rochester, MN
    Areas of focus:

    Echocardiogram, Hypoplastic left heart syndrome, Congenital heart disease, Heart disease, Congenital heart defects in c...hildren

Research

Researchers at Mayo Clinic study new treatments and surgeries for people who have hypoplastic left heart syndrome and other congenital heart diseases. Ongoing research includes studies in imaging and outcomes, human genetics, and regenerative medicine strategies. Mayo Clinic health care providers are also assembling personal and family histories, heart images, tissue and cell samples, and genomic information of people with hypoplastic left heart syndrome and their family members to further study the condition.

Specialized research

Mayo Clinic's Todd and Karen Wanek Family Program for Hypoplastic Left Heart Syndrome is a specialized center dedicated to discovering new ways to diagnose and treat hypoplastic left heart syndrome. Research projects include using stem cells to strengthen the heart and searching for genes that may be responsible for hypoplastic left heart syndrome.

Read more about research in the Todd and Karen Wanek Family Program for Hypoplastic Left Heart Syndrome (HLHS).

Publications

See a list of publications about hypoplastic left heart syndrome by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Pioneering Treatment for Hypoplastic Left Heart Syndrome

Mayo Clinic Using Regenerative Medicine to Find Answers for Hypoplastic Left Heart Syndrome

I'm Tim Nelson. I'm the director of the Todd and Karen Wanek family program for hypoplastic left heart research. This hypoplastic left heart research program here at Mayo Clinic comprises of nearly 60 people that work across the enterprise in multiple different areas of basic science all the way to clinical practice.

Our research program is dedicated to children with congenital heart disease with a condition specifically known as hypoplastic left heart. These children are born without a half of their heart and literally require three open heart surgeries to allow their heart to function and be compatible with life. Unfortunately, these hearts are not strong enough to live a normal sustain life span and the need for transplantation becomes real.

Our goal in our program is to invent and discover new regenerative stem cell-based therapies that allows us to rebuild these hearts make them bigger better and stronger with the goal of delaying or even preventing the need for cardiac transplantation down the road.

This multidisciplinary team works across the spectrum of research and discovery all the way to clinical applications. This multidisciplinary team is understanding the genetics, the natural history, and how stem cells work in these babies bodies when they are born. And by understanding the problem we then can engineer a solution. And today we have a clinical trial that we're currently offering patients where we actually use the umbilical cord blood collected at the time of their birth, processed and delivered into their heart muscle at the time of one of their elective surgeries. By doing this we hope that we can show that technology is safe in the congenital heart disease situation and ultimately be able to rebuild and strengthen the heart tissue to make it bigger, better and stronger. As we do the research in the lab and in the clinical setting, we're hoping to constantly improve and iteratively improve upon the cells that we use so we can grow better tissue that's stronger and more effective sustaining cardiac function and ultimately delaying in preventing transplant for children with hypoplastic left heart.

Research Profiles

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By Mayo Clinic Staff

Hypoplastic left heart syndrome care at Mayo Clinic

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Diagnosis & treatmentCare at Mayo Clinic
Aug. 12, 2022
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Hypoplastic left heart syndrome

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Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight.