Orthopedic Surgery

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. A Study to Assess Outcomes of Operatively-treated Interprosthetic Femur Fractures.

   Rochester, Minn.

   The purpose of this study is to retrospectively assess the treatment modality, survivorship, reoperation, and complication rates among patients with interprosthetic femur fractures (those occurring between an ipsilateral hip and knee arthroplasty).

2. Early Outcomes of Volar Capsulodesis for the Treatment of Scapholunate Ligament Injury

   Rochester, Minn.

   The purpose of this study is to:

   1. To provide a comprehensive review of Mayo Clinic’s experience with volar SLIL capsulodesis
   2. Investigate the relationships between patient risk factors and clinical variables with functional outcomes and patient satisfaction
   3. Determine rates of complication, revision surgeries and salvage for failure

3. A Study of the Concentration of Mesenchymal Stem Cells in the Joint Fluid of the Hip in Patients who have Bone Necrosis

   Rochester, Minn.

   The purpose of this study is to determine if the concentration of mesenchymal stem cells in the joint fluid of the hip increases to compare with the severity of the disease in patients with osteonecrosis ( bone decay) of the femoral head (leg bone/hip joint).

4. A Study to Implement a Patient-Centered Pain Plan and Standardized Preoperative Pain Education for Patients Undergoing Lumbar Procedures

   Mankato, Minn.

   The purpose of this study is to develop a patient-centered pain plan and standardized preoperative pain education for patients undergoing lumbar procedures to increase postoperative pain control and patient satisfaction.

5. Genetic Expression in Osteolysis, Infection, Arthrofibrosis & Metal Reactions in THA & TKA: A Microarray Analysis to Characterize Individual Host Response to the Molecular Mechanisms of Loosening and Arthrofibrosis

   Rochester, Minn.

   This study is being conducted to determine gene and protein expression profiles (i.e. which genes and proteins are turned off and on) of those with a possibility of developing osteolysis, infection, arthrofibrosis or metallosis of their THA/TKA.

6. A Study to Create a Registry of Non-Fusion Spinal Deformity Correction in Adolescent Idiopathic Scoliosis

   Rochester, Minn., Minneapolis, Minn.

   The primary purpose of this study is to evaluate the effectiveness of non-fusion surgical treatment of Spinal Deformity Correction in Adolescent Idiopathic Scoliosis.

   The Post Approval Study (PAS) is gathering data on the Tether device and it's efficacy and safety.

7. A Study Comparing the Outcome of a Large-Diameter versus Small-Diameter Glenosphere (Shoulder/Arm Ball-Joint) in Primary Reverse Shoulder Arthroplasty

   Rochester, Minn.

   The purpose of this study is to compare the outcome of primary reverse shoulder arthroplasty using the Stryker ReUnion System with the implantation of either a large (40 mm) or a small (36 mm) glenosphere (shoulder to arm, ball shaped joint).

8. A Study to Validate the Patient-Specific Functional Survey in Patients with Carpal Tunnel Syndrome

   Rochester, Minn.

   The purpose of this study is to determine if the Patient-Specific Functional Survey (PSFS) is a valid and reliable measure to evaluate functional difficulties with carpal tunnel syndrome.

9. A Study to Evaluate Low-Intensity Blood Flow Restriction Training to Improve Post-Operative Outcomes for ACL Reconstruction

   Scottsdale/Phoenix, Ariz.

   The purpose of this study is to analyze the difference between the Blood Flow Restriction (BFR) and SHAM-BFR groups in change in muscle diameter (hypertrophy) from 2 weeks pre-operative to 8-10 days post-operative.

10. A Study to Analyze the Regenerative Properties of Derived Mesenchymal Stem Cells of Circulating miRNA Biomarker for Osteonecrosis

    Rochester, Minn.

    The purpose of this study is to define the functionality of adipose-derived regenerative cells (ADRCs) and bone marrow concentrate (BMC) for a fundamental mechanistic understanding of these two regenerative cell populations.