Orthopedic Surgery

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. Direct Anterior vs. Anterolateral Approach for Hip Arthroplasty After Femoral Neck Fracture in the Senior Population

   Rochester, Minn.

   Displaced femoral neck fractures are one group of hip fracture patients that are commonly treated with cemented hemiarthroplasty (HA) or total hip arthroplasty (THA). In the elective hip arthroplasty population, the direct anterior approach (DAA) has shown to be effective in helping patients to quickly obtain high postoperative function. This approach has also been shown to be effective in arthroplasty for displaced femoral neck fractures in a few studies. However, the only studies that directly compare two approaches for hip arthroplasty for femoral neck fractures utilize the anterolateral approach (ALA) versus posterior approach (PA) or DAA versus PA. No studies of which we are aware directly compare the DAA to the ALA. The DAA and ALA are the two most popular approaches for bipolar hemiarthroplasty at our institution, so we are setting out to determine the differences between them.

2. A Study of Screening High School, Collegiate, and Olympic/Professional-level Athletes for Characteristics that May Lead to Injury

   Rochester, Minn.

   The purpose of this study is to perform comprehensive clinical and biomechanical screening of high school, collegiate-level, and Olympic/professional-level athletes to identify individual functional and performance deficits that can lead to non-contact lower extremity injury.

3. 4DCT Imaging for Improved Diagnosis and Treatment of Wrist Ligament Injuries

   Rochester, Minn.

   The study seeks to determine whether the 4DCT imaging technique can be used to replace current invasive diagnostic tests for ligament injuries of the wrist.

4. A Study to Evaluate Preventative Saphenous Nerve Neurectomy in Primary Total Knee Arthroplasty

   Jacksonville, Fla.

   The purpose of this study is to evaluate the incidence of chronic knee pain at 6 months following primary total knee arthroplasty. Secondary outcomes include incidence of knee numbness, postoperative sensory loss or change at the knee, range of motion (ROM), resting pain with Visual Analog Scale (VAS), Knee Injury and Osteoarthritis Outcome Score (KOOS), quality of life measurement assessed by SF-36.

5. A Study to Evaluate Operative versus Non-operative Intervention of Posterior Malleolar Fractures Involving Less than 25% of the Articular Surface

   Rochester, Minn.

   The purpose of this study is determine if posterior malleolar fractures involving less than 25% of the articular surface should undergo operative intervention to improve clinical outcomes.

6. A Study of Clinical Outcomes of Ultrasound-guided Carpal Tunnel Release Performed in a Procedural Room Setting

   Albert Lea, Minn.

   The purpose of this study is to document the primary investigator’s clinical experience performing Ultrasound Guided Carpal Tunnel Release (USCTR) in the clinic procedure room setting through retrospective and prospective analysis of these now routinely collected clinical outcomes. 

7. A Study of Motor Unit Recruitment During Isometric Contractions in Human Muscles

   Rochester, Minn.

   The purpose of this study is to investigate motor unit recruitment during  isometric contractions in human muscles.

8. A Study of the Concentration of Mesenchymal Stem Cells in the Joint Fluid of the Hip in Patients who have Bone Necrosis

   Rochester, Minn.

   The purpose of this study is to determine if the concentration of mesenchymal stem cells in the joint fluid of the hip increases to compare with the severity of the disease in patients with osteonecrosis ( bone decay) of the femoral head (leg bone/hip joint).

9. Genetic Expression in Osteolysis, Infection, Arthrofibrosis & Metal Reactions in THA & TKA: A Microarray Analysis to Characterize Individual Host Response to the Molecular Mechanisms of Loosening and Arthrofibrosis

   Rochester, Minn.

   This study is being conducted to determine gene and protein expression profiles (i.e. which genes and proteins are turned off and on) of those with a possibility of developing osteolysis, infection, arthrofibrosis or metallosis of their THA/TKA.

10. A Study of Normal Subsynovial Connective Tissue and Carpal Tunnel Syndrome

    Rochester, Minn.

    The purpose of this study is to collect normal tissue as the control for a study looking at the role of synovial fibrosis in the development of carpal tunnel syndrome.