Orthopedic Surgery

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. 4DCT Imaging for Improved Diagnosis and Treatment of Wrist Ligament Injuries

   Rochester, Minn.

   The study seeks to determine whether the 4DCT imaging technique can be used to replace current invasive diagnostic tests for ligament injuries of the wrist.

2. Direct Anterior vs. Anterolateral Approach for Hip Arthroplasty After Femoral Neck Fracture in the Senior Population

   Rochester, Minn.

   Displaced femoral neck fractures are one group of hip fracture patients that are commonly treated with cemented hemiarthroplasty (HA) or total hip arthroplasty (THA). In the elective hip arthroplasty population, the direct anterior approach (DAA) has shown to be effective in helping patients to quickly obtain high postoperative function. This approach has also been shown to be effective in arthroplasty for displaced femoral neck fractures in a few studies. However, the only studies that directly compare two approaches for hip arthroplasty for femoral neck fractures utilize the anterolateral approach (ALA) versus posterior approach (PA) or DAA versus PA. No studies of which we are aware directly compare the DAA to the ALA. The DAA and ALA are the two most popular approaches for bipolar hemiarthroplasty at our institution, so we are setting out to determine the differences between them.

3. A Study of Screening High School, Collegiate, and Olympic/Professional-level Athletes for Characteristics that May Lead to Injury

   Rochester, Minn.

   The purpose of this study is to perform comprehensive clinical and biomechanical screening of high school, collegiate-level, and Olympic/professional-level athletes to identify individual functional and performance deficits that can lead to non-contact lower extremity injury.

4. Preservation of Joint Function Using Postoperative Continuous Passive Motion (CPM) A Pilot Study

   Rochester, Minn.

   This pilot study is designed to determine if the rehabilitative benefits of continuous passive motion (CPM) will help preserve/restore the joint function and significantly improve the rate of recovery of patients after the surgical release of elbow contractures better than standard physiotherapy and static splinting.

5. A Study of Clinical Outcomes of Ultrasound-guided Carpal Tunnel Release Performed in a Procedural Room Setting

   Albert Lea, Minn.

   The purpose of this study is to document the primary investigator’s clinical experience performing Ultrasound Guided Carpal Tunnel Release (USCTR) in the clinic procedure room setting through retrospective and prospective analysis of these now routinely collected clinical outcomes. 

6. A Study to Evaluate Preventative Saphenous Nerve Neurectomy in Primary Total Knee Arthroplasty

   Jacksonville, Fla.

   The purpose of this study is to evaluate the incidence of chronic knee pain at 6 months following primary total knee arthroplasty. Secondary outcomes include incidence of knee numbness, postoperative sensory loss or change at the knee, range of motion (ROM), resting pain with Visual Analog Scale (VAS), Knee Injury and Osteoarthritis Outcome Score (KOOS), quality of life measurement assessed by SF-36.

7. Outcomes of Meniscus Root Repair Using a Transtibial Pullout Technique

   Rochester, Minn.

   The results of this study will optimize the care for patients with a meniscus root tear. Surgeons will be able to determine if MRR (meniscus root repair) with transtibial pullout technique is an effective treatment and will identify potential risk factors for poor clinical outcomes. In addition, investigators will determine if MRR is successful in delaying the radiographic progression of arthritis in the involved compartment.

8. Quality of Life Following Sacral Resection

   Rochester, Minn.

   The purpose of this study is to survey patients who have undergone a sacrectomy (partial or total) at the Mayo Clinic.

9. A Study of Hand Patterns in Children While Grasping Objects of Daily Use

   Rochester, Minn.

   The purpose of this study to observe and understand the various postures used by a child's hand for grasping things in their everyday activities. These postures will be used to form the design and implementation of myoelectric hand prosthesis for children.

10. Genetic Expression in Osteolysis, Infection, Arthrofibrosis & Metal Reactions in THA & TKA: A Microarray Analysis to Characterize Individual Host Response to the Molecular Mechanisms of Loosening and Arthrofibrosis

    Rochester, Minn.

    This study is being conducted to determine gene and protein expression profiles (i.e. which genes and proteins are turned off and on) of those with a possibility of developing osteolysis, infection, arthrofibrosis or metallosis of their THA/TKA.