Clinical trials Below are current clinical trials.60 studies in Orthopedic Surgery (open studies only). Filter this list of studies by location, status and more. A Study of Clinical Outcomes of Ultrasound-guided Carpal Tunnel Release Performed in a Procedural Room Setting Albert Lea, Minn. The purpose of this study is to document the primary investigator’s clinical experience performing Ultrasound Guided Carpal Tunnel Release (USCTR) in the clinic procedure room setting through retrospective and prospective analysis of these now routinely collected clinical outcomes. A Study to Evaluate Preventative Saphenous Nerve Neurectomy in Primary Total Knee Arthroplasty Jacksonville, Fla. The purpose of this study is to evaluate the incidence of chronic knee pain at 6 months following primary total knee arthroplasty. Secondary outcomes include incidence of knee numbness, postoperative sensory loss or change at the knee, range of motion (ROM), resting pain with Visual Analog Scale (VAS), Knee Injury and Osteoarthritis Outcome Score (KOOS), quality of life measurement assessed by SF-36. A Study to Evaluate Outcomes of Pectoralis Minor and Brachial Plexus Release Rochester, Minn. The purpose of this study is to to assess the clinical and radiographic outcomes of patients who have undergone shoulder arthroplasty. Early Outcomes of Volar Capsulodesis for the Treatment of Scapholunate Ligament Injury Rochester, Minn. The purpose of this study is to: To provide a comprehensive review of Mayo Clinic’s experience with volar SLIL capsulodesis Investigate the relationships between patient risk factors and clinical variables with functional outcomes and patient satisfaction Determine rates of complication, revision surgeries and salvage for failure Genetic Expression in Osteolysis, Infection, Arthrofibrosis & Metal Reactions in THA & TKA: A Microarray Analysis to Characterize Individual Host Response to the Molecular Mechanisms of Loosening and Arthrofibrosis Rochester, Minn. This study is being conducted to determine gene and protein expression profiles (i.e. which genes and proteins are turned off and on) of those with a possibility of developing osteolysis, infection, arthrofibrosis or metallosis of their THA/TKA. A Study to Create a Registry of Non-Fusion Spinal Deformity Correction in Adolescent Idiopathic Scoliosis Rochester, Minn., Minneapolis, Minn. The primary purpose of this study is to evaluate the effectiveness of non-fusion surgical treatment of Spinal Deformity Correction in Adolescent Idiopathic Scoliosis. The Post Approval Study (PAS) is gathering data on the Tether device and it's efficacy and safety. Knee Biologic Preservation: Functional and Clinical Outcome Rochester, Minn. The main purpose of this study is to evaluate the clinical and functional outcomes of patients undergoing biologic knee preservation surgery. Secondary purpose is to identify possible correlation between outcome and pre-operative radiological findings (i.e. bony abnormalities such as mal-alignment, size of cartilage defect). A Study to Validate the Patient-Specific Functional Survey in Patients with Carpal Tunnel Syndrome Rochester, Minn. The purpose of this study is to determine if the Patient-Specific Functional Survey (PSFS) is a valid and reliable measure to evaluate functional difficulties with carpal tunnel syndrome. Detection of Infection in Arthroplasty Rochester, Minn. The purpose of this study is to determine the sensitivity, specificity, positive and negative predictive values of molecular detection of microorganisms, detection of microbial proteins and antibodies against microorganisms, and inflammatory markers (e.g., leukocyte esterase, CRP) in synovial fluid for the diagnosis of prosthetic joint infection (PJI). A Study to Evaluate Manipulation Under Anesthesia After Bilateral Primary Total Knee Arthroplasty Rochester, Minn. The purpose of this study is to determine unique genetic profile of patients requiring MUA following bilateral pTKA via genetic sequencing, to determine outcomes of patients receiving MUA in terms of KSS, implant durability, survival free of reoperation, and to define characteristics and comorbidities of patients undergoing unilateral and bilateral MUA. 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So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight. SectionsRequest an AppointmentOverviewTests & proceduresConditions treatedDoctorsSpecialty groupsExpertise & rankingsClinical trialsResearchPatient storiesCosts & insuranceNews from Mayo ClinicReferrals ORG-20126458 Medical Departments & Centers Orthopedic Surgery