Neuromuscular Disease Group Overview Print Neuromuscular diseases affect the function of muscles due to problems with the nerves and muscles in your body. The most common symptom of these diseases is muscle weakness. Mayo Clinic neurologists provide comprehensive evaluation of these diseases, including electrodiagnostic studies and other tests. Conditions and symptoms Amyotrophic lateral sclerosis (ALS) Botulism Congenital myasthenic syndromes Congenital myopathies Cramp-fasciculation syndrome Elevated creatine kinase Fasciculations Inclusion-body myositis Lambert-Eaton syndrome Mitochondrial myopathy Motor neuron disease Muscle disorders Muscular dystrophy Myasthenia gravis Myotonic dystrophy Neuromuscular junction disorders Neuromyotonia (Isaacs syndrome) Peripheral neuropathy Polymyositis ResearchDoctors are active in clinical and laboratory research to improve the diagnosis and treatment of people with neuromuscular diseases. Read about research in neuromuscular diseases and ALS. Nationally recognized expertise Mayo Clinic in Rochester, Minn., and Mayo Clinic in Jacksonville, Fla., are ranked among the Best Hospitals for neurology and neurosurgery by U.S. News & World Report. Mayo Clinic in Phoenix/Scottsdale, Ariz., is ranked high-performing for neurology and neurosurgery by U.S. News & World Report. Mayo Clinic also ranks among the Best Children's Hospitals for neurology and neurosurgery. Request an Appointment at Mayo Clinic Sept. 25, 2020 Print Share on: FacebookTwitter NeurologyDepartment homeSectionsRequest an appointmentOverviewTests & proceduresConditions treatedDoctorsSpecialty groupsExpertise & rankingsLocations, travel & lodgingClinical trialsResearchThe Mayo Clinic experience & patient storiesCosts & insuranceNews from Mayo ClinicResources for medical professionals ORG-20118156 Departments & Centers Medical Departments & Centers Neurology