Below are current clinical trials.6 studies in Lung Transplant Program
(open studies only).
Filter this list of studies by location, status and more.
The purpose of this study is to:
- Demonstrate pharmacogenetic variability in the Mayo Clinic Florida lung transplant population.
- Describe patterns in tacrolimus levels in the context of pharmacogenomic profiles
- Use pharmacogenomic data to establish a need for therapeutic drug monitoring in selected other drugs
- Use pharmacogenomic data, in combination with knowledge of drug interactions, to establish sensitivity to tacrolimus dose changes
To create a biorepository of fluid [lung lavage], blood and tissue specimens [explanted diseased lung tissue from the recipient and serial lung biopsy specimens after transplant] for future studies.
The objective of this study is to obtain preliminary data to evaluate the accuracy of non-invasive blood pressure measurement in patients supported by continuous-flow left ventricular assist device (LVAD) using non-invasive supra-systolic methods in highly sensitive experimental blood pressure monitor.
To assess the safety and feasibility of mesenchymal stem cells therapy in patients with transplant related bronchiolitis obliteran syndrome (BOS).
This is a safety study to compare the safety of receiving a lung treated with the Toronto EVLP System™ by SPONSOR in SPONSOR's dedicated facility against standard lung transplantation.
Jacksonville, Fla., Rochester, Minn.
The purpose of this study is to determine if DNA originating from the transplanted heart or lung can be detected in the blood and used to monitor for rejection.
Sept. 11, 2018
- Scientific Registry of Transplant Recipients. http://www.srtr.org/default.aspx. Accessed July 14, 2016.
- U.S. News Best Hospitals 2015-16. U.S. News & World Report. http://health.usnews.com/best-hospitals/rankings. Accessed Feb. 22, 2016.
- Riggin EA. Allscripts EPSi. Mayo Clinic, Rochester, Minn. June 22, 2016.
- Erasmus DB (expert opinion). Mayo Clinic, Jacksonville, Fla. August 3, 2016.
- AskMayoExpert. Lung transplantation. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2015.
- Barbara Woodward Lips Patient Education Center. About your lung transplant. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2006.
- Hachem RR. Lung transplantation: General guidelines for recipient selection. http://www.uptodate.com/home. Accessed July 15, 2016.
- Barbara Woodward Lips Patient Education Center. Planning for your transplant: A financial guide. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2009.
- Sherman W, et al. Lung transplantation and coronary artery disease. The Annals of Thoracic Surgery. 2011;92:303.
- What is coronary angiography? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/ca/. Accessed July 15, 2016.
- What is a tracheostomy? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/trach/. Accessed July 15, 2016.
- What is a lung transplant? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/lungtxp/. Accessed July 15, 2016.
- Wilson ME, et al. Pretransplant frailty is associated with decreased survival after lung transplantation. The Journal of Heart and Lung Transplantation. 2016;35:173.
- Chandrashekaran S, et al. Weight loss prior to lung transplantation is associated with improved survival. The Journal of Heart and Lung Transplantation. 2015;34:651.
- Aho JM, et al. Closure of a recurrent bronchopleural fistula using a matrix seeded with patient-derived mesenchymal stem cells. Stem Cells Translational Medicine. 2016;5:1. http://www.stemcellstm.com. Accessed July l5, 2016.
- Single-lung transplant patient discharged. Mayovox. August 1990;37:9.
- Halum SL. A multi-institutional analysis of tracheotomy complications. Laryngoscope. 2012;122:38.