Lung Transplant Program

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. Pharmacogenetics in Lung Transplant Patients

   Jacksonville, Fla.

   The purpose of this study is to:

   • Demonstrate pharmacogenetic variability in the Mayo Clinic Florida lung transplant population.
   • Describe patterns in tacrolimus levels in the context of pharmacogenomic profiles
   • Use pharmacogenomic data to establish a need for therapeutic drug monitoring in selected other drugs
   • Use pharmacogenomic data, in combination with knowledge of drug interactions, to establish sensitivity to tacrolimus dose changes

2. Lung Biorepository

   Scottsdale/Phoenix, Ariz.

   To create a biorepository of fluid [lung lavage], blood and tissue specimens [explanted diseased lung tissue from the recipient and serial lung biopsy specimens after transplant] for future studies.

3. High Sensitive Multichannel Non-Invasive Blood Pressure Monitor

   Rochester, Minn.

   The objective of this study is to obtain preliminary data to evaluate the accuracy of non-invasive blood pressure measurement in patients supported by continuous-flow left ventricular assist device (LVAD) using non-invasive supra-systolic methods in highly sensitive experimental blood pressure monitor.

4. Mesenchymal Stem Cell Therapy for Lung Rejection

   Jacksonville, Fla.

   To assess the safety and feasibility of mesenchymal stem cells therapy in patients with transplant related bronchiolitis obliteran syndrome (BOS).

5. Extending Preservation and Assessment Time of Donor Lungs Using the Toronto EVLP System™ at a Dedicated EVLP Facility

   Jacksonville, Fla.

   This is a safety study to compare the safety of receiving a lung treated with the Toronto EVLP System™ by SPONSOR in SPONSOR's dedicated facility against standard lung transplantation.

6. Donor-Specific Cell Free DNA Monitoring of Thoracic Allografts

   Jacksonville, Fla., Rochester, Minn.

   The purpose of this study is to determine if DNA originating from the transplanted heart or lung can be detected in the blood and used to monitor for rejection.