Liver transplant specialists work together to diagnose and treat people with challenging liver conditions. Liver transplant team discussion at Mayo Clinic

Liver transplant experts work together to provide exactly the care each patient needs.

Health History Questionnaire

Interested in being a living kidney or liver donor? Start the process by completing a Health History Questionnaire.

Living Donor Toolkit

Learn what transplant recipients and living donors can expect: tests, screening, the procedure, risks, recovery, financial information and more.

Mayo Clinic's liver transplant doctors and surgeons use proven innovations to successfully treat people with liver failure and other complications of liver conditions. Their expertise with living-donor transplant, a fast-track recovery process and multiorgan transplants are part of why people turn to the Mayo Clinic Liver Transplant Program.

As part of a three-site institution, Mayo Clinic surgeons perform more than 300 liver transplants a year, including for people with very challenging health situations who need specialized solutions and surgeries. And they are leaders in living-donor liver transplants, an option that improves access to transplantation and results in better patient outcomes.

Your care team provides comprehensive care tailored to your needs. Liver transplant care

Your care team works with you every step of the way, from preoperative testing through recovery.

Mayo Clinic's liver transplant experts focus on your needs, bringing to your situation the strength of their:

  • Experience. As a three-site institution, Mayo Clinic has one of the largest liver transplant programs in the United States. Its liver transplant team is recognized nationally and internationally for its expertise in comprehensive specialty treatment for people with serious liver conditions.

    Mayo Clinic's extensive experience is reflected in the high quality of care and above-average survival rates for liver transplant patients. In 2014, Mayo Clinic's campus in Phoenix, Arizona, was identified as having the highest one-year patient survival rate in the United States for adult liver transplantation.

  • Teamwork. By working together, your doctors, nurses, pharmacists, social workers, dietitians and other health professionals take care of you before, during and after transplant. They provide quality care focused on the needs of you and your family.

    These experts collaborate with you and a multidisciplinary team of doctors in digestive diseases (gastroenterology and hepatology), radiology, pathology, infectious disease management and other specialties to provide exactly the care you need.

  • Advanced technology. The innovations and technology of Mayo Clinic's liver transplant team make transplants available to more people. Our doctors and surgeons offer specialized procedures available at only a small number of institutions. These services include heart-liver transplants, treatment for bile duct cancer and treating obese patients who need a liver transplant with weight loss surgery (sleeve gastrectomy).
  • Innovative research. Mayo Clinic researchers study how to limit immune system rejection after a liver transplant, how to use cell therapies to improve outcomes and many other aspects of transplant that affect patients' experiences.

    At Mayo Clinic, you may have access to ongoing clinical trials and new treatments.

    Every day the Transplant Research Center brings together surgeons, hepatologists, hematologists, experts in human cell therapy and scientists from many other fields and institutions to collaborate. For example, Mayo Clinic is a leader in developing a bioartificial liver and a new approach to treating obese people who need a liver transplant.

Mayo Clinic surgeons perform liver transplants at Mayo Clinic's campuses in Arizona, Florida and Minnesota. Liver transplant in children is provided at Mayo Clinic in Rochester, Minnesota. Mayo Clinic's campus in Arizona partners with Phoenix Children's Hospital to treat children who may need liver transplants.


Mayo Clinic liver doctors and surgeons have expertise treating people in many areas of liver transplant, including those listed below. Not all services are available at each of Mayo Clinic's three campuses, in Arizona, Florida and Minnesota. Please confirm when you call for an appointment.

  • Multiorgan transplants, such as heart-liver and liver-kidney
  • Liver transplant for children
  • Living-donor liver transplant
  • Transplantation in people who are hepatitis C positive
  • Specialized treatment for obese people who need a liver transplant
  • Specialized treatment for people with a type of bile duct cancer called hilar cholangiocarinoma
  • Domino liver transplant
  • Novel strategies to prevent the immune system from rejecting donated tissue
  • Optimized use of extended-criteria organ donors, which helps people on a waiting list get transplanted sooner
Liver transplant surgeons work with a multidisciplinary team to perform complex procedures. Liver transplant surgeons

Liver transplant surgeons use advanced techniques.

Jan. 17, 2018
  1. Scientific Registry of Transplant Recipients. http://www.srtr.org/default.aspx. April 11, 2016.
  2. U.S. News & World Report. U.S. News Best Hospitals 2015-16. http://health.usnews.com/best-hospitals/rankings. Accessed Feb. 22, 2016.
  3. Barbara Woodward Lips Patient Education Center. Liver transplant. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2013.
  4. Eggebraaten KR (expert opinion). Mayo Clinic, Rochester, Minn. May 23, 2016.
  5. Barbara DW, et al. The perioperative management of patients undergoing combined heart-liver transplantation. Transplantation. 2015;99:139.
  6. Bulatao IG, et al. Avoiding stay in the intensive care unit after liver transplantation: A score to assign location of care. American Journal of Transplantation. 2014;14:2088.
  7. Heimbach JK (expert opinion). Mayo Clinic, Rochester, Minn. June 28, 2016.
  8. Stulak JM, et al. Combined heart and abdominal organ transplantation: Excellent outcomes gained from a unique experience. Journal of Heart and Lung Transplantation. 2014;33:S278.
  9. Ibrahim SH (expert opinion). Mayo Clinic, Rochester, Minn. June 14, 2016.
  10. Glorioso JM, et al. Pivotal preclinical trial of the spheroid reservoir bioartificial liver. Journal of Hepatology. 2015;63:388.
  11. Heimbach JK, et al. Combined liver transplantation and gastric sleeve resection for patients with medically complicated obesity and end-stage liver disease. American Journal of Transplantation. 2013;13:363.
  12. Murad SD, et al. Long-term clinical and radiological follow up of living liver donors. Liver Transplantation. In press. Accessed May 11, 2016.
  13. Murad SD, et al. Predictors of pretransplant dropout and posttransplant recurrence in patients with perihilar cholangiocarcinoma. Hepatology. 2012;56:973.
  14. Barbara Woodward Lips Patient Education Center. About your child's liver transplant. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2009.
  15. Rizvi S, et al. Primary sclerosing cholangitis as a premalignant biliary tract disease: Surveillance and management. Clinical Gastroenterology and Hepatology. 2015;13:2152.
  16. Taner T, et al. Decreased chronic cellular and antibody-mediated injury in the kidney following simultaneous liver-kidney transplantation. Kidney International. 2016;89:909.
  17. Watt KD, et al. A practical guide to the management of HCV infection following liver transplantation. American Journal of Transplantation. 2009;9:1707.
  18. Rosen CB, et al. Liver transplantation for cholangiocarcinoma. Transplant International. 2010;23:692.
  19. Raichlin E, et al. Combined heart and liver transplantation: A single-center experience. Transplantation. 2009;88:219.
  20. Nagourney E. 'Domino' transplants: Rare and risky. The New York Times. http://www.nytimes.com/2000/05/02/health/domino-transplants-rare-and-risky.html. Accessed May 12, 2016.
  21. Kitchens WH. Domino liver transplantation: Indications, techniques, and outcomes. Transplantation Reviews. 2011;25:167.
  22. Yu Y, et al. Cell therapies for liver diseases. Liver Transplantation. 2012;18:9.
  23. Croome KP, et al. The use of donation after cardiac death allografts does not increase recurrence of hepatocellular carcinoma. American Journal of Transplantation. 2015;15:2704.
  24. De Assuncao TM, et al. Development and characterization of human-induced pluripotent stem cell-derived cholangiocytes. Laboratory Investigation. 2015;95:684.
  25. Riggin EA. Allscripts EPSi. Mayo Clinic, Rochester, Minn. Feb. 15, 2016.
  26. Brown AY. Allscripts EPSi. Mayo Clinic, Rochester, Minn. March 22, 2016.
  27. Cook AJ. Allscripts EPSi. Mayo Clinic, Rochester, Minn. May 2, 2014.
  28. Krowka MJ, et al. International Liver Transplant Society practice guidelines: Diagnosis and management of hepatopulmonary syndrome and portopulmonary hypertension. Transplantation. 2016;100:1440.
  29. Patel K, et al. FibroSURE and FibroScan in relation to treatment response in chronic hepatitis C virus. World Journal of Gastroenterology. 2011;17:4581.
  30. Singh S, et al. Magnetic resonance elastography for staging liver fibrosis in non-alcoholic fatty liver disease: A diagnostic accuracy systematic review and individual participant data pooled analysis. European Radiology. 2016;26:1431.
  31. Han L, et al. Extracorporeal liver support and liver transplant for patients with acute-on-chronic liver failure. Seminars in Liver Disease. 2016;36:153. https://www.thieme-connect.de/products/ejournals/html/10.1055/s-0036-1583197. Accessed June 29, 2016.
  32. Gallagher C. Transplant genomics enters collaboration with Mayo Clinic (news release). Mayo Clinic, Rochester, Minn. June 27, 2016.
  33. Heilman RL (expert opinion). Mayo Clinic, Phoenix/Scottsdale, Ariz. June 24, 2016.