Heart transplant for children

Experts in pediatric heart transplant understand the unique challenges of children undergoing surgery. Pediatric heart transplant

Mayo Clinic's pediatric heart transplant program is located at the Rochester, Minn., campus. The program evaluates pediatric patients from newborns to teenagers who may need advanced cardiac support or heart transplant.

At Mayo Clinic's campus in Minnesota, pediatricians and doctors trained in treating children with heart disease evaluate and treat children who may need heart transplants (pediatric cardiologists). Children needing hospitalization receive care at Mayo Eugenio Litta Children's Hospital, located within Mayo Clinic Hospital, Saint Marys Campus, in Rochester, Minnesota.

At Mayo Clinic's campus in Arizona, doctors trained in heart diseases (cardiologists) partner with Phoenix Children's Hospital to treat teenagers and young adults with congenital heart disease.

Why choose Mayo Clinic for my child's heart transplant?

In some ways, the process for heart transplant in children — from newborn to adolescent — is similar to that for adults. But because children with heart disease face unique challenges, they will benefit from the extensive experience of Mayo Clinic pediatric heart transplant experts:

  • Pediatric transplant surgeons use specialized pediatric surgical techniques and understand how to make a transplant work for patients with complex congenital heart defects.
  • Pediatric cardiologists understand how a child's body processes the drugs needed to prevent complications.
  • A multidisciplinary pediatric team works with you and your child throughout the transplant process. This team includes dedicated pediatric heart surgeons, pharmacists, dietitians, physical therapists, clinical nurse specialists, physician assistants and nurses. It usually includes social workers, child-life specialists, chaplains and transplant financial coordinators as well.
  • If a child has a familial form of heart failure, there's a risk that others in the family may have the same thing. We can screen other family members, sometimes all in one day.

In addition, Mayo Clinic doctors have special expertise in treating children with congenital heart defects. And they partner with scientists to research genetics and new treatments for congenital heart disease, including hypoplastic left heart syndrome. Read more about research in the Todd and Karen Wanek Family Program for Hypoplastic Left Heart Syndrome.

Nationally recognized expertise

Mayo Clinic in Rochester, Minn., Mayo Clinic in Phoenix/Scottsdale, Ariz., and Mayo Clinic in Jacksonville, Fla., are ranked among the Best Hospitals for heart and heart surgery by U.S. News & World Report. Mayo Clinic Children's Center in Rochester, Minn., is ranked among the Best Children's Hospitals for heart and heart surgery by U.S. News & World Report.

Where will the new heart come from?

The transplant team evaluates your child to determine the most appropriate treatment for his or her heart condition, which may include a heart transplant or other heart surgery. If the team determines your child is eligible for a heart transplant, he or she will be placed on a waiting list for a donor heart.

Who will do the surgery?

Your child's surgery will be performed by a pediatric operating team, led by a pediatric cardiac surgeon.

What can I expect after my child's surgery?

How long your child stays in the hospital after surgery depends on his or her medical condition and recovery. The transplant team will monitor your child's recovery.

After your child has left the hospital, you and your child will need to stay near Rochester, Minnesota, for about three months so that doctors can monitor his or her recovery. Your child will have regular follow-up appointments to check for signs of rejection. After the transplant, a transplant coordinator who is a registered nurse will provide your child with continuing care.

The transplant team will work closely with your primary care doctor to coordinate care close to home once your child has completed your recovery period.

Most heart transplants in children are successful. Children with a new heart will need medicines for the rest of their life to help prevent complications. And they'll need to visit a doctor regularly to make sure the new heart is working properly.

Pediatric heart transplant care video, Dr. Johnson

Sept. 11, 2018
  1. Scientific Registry of Transplant Recipients. http://www.srtr.org/default.aspx. Accessed May 13, 2016.
  2. U.S. News & World Report. U.S. News Best Hospitals 2015-16. http://health.usnews.com/best-hospitals/rankings. Accessed Feb. 22, 2016.
  3. Cook AJ. Allscripts EPSi. Mayo Clinic, Rochester, Minn. May 2, 2014.
  4. Heart transplant program to resume in fall of 1986. Mayovox. 1986:37;1.
  5. Mancini D. Indications and contraindications for cardiac transplantation. http://www.uptodate.com/home. Accessed April 22, 2016.
  6. Barbara Woodward Lips Patient Education Center. Heart transplant. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2013.
  7. Yip DS (expert opinion). Mayo Clinic, Jacksonville, Fla. June 20, 2016.
  8. Barbara Woodward Lips Patient Education Center. Your child's heart transplant. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2013.
  9. Johnson JN (expert opinion). Mayo Clinic, Rochester, Minn. June 20, 2016.
  10. Vucicevic D, et al. Sirolimus based immunosuppression results in lower incidence of post-transplantation lymphoproliferative disorders in heart transplant recipients. Journal of Heart and Lung Transplantation. 2015;34:s86.
  11. Kalya A, et al. Role of total artificial heart in the management of heart transplant rejection and retransplantation: Case report and review. Clinical Transplantation. 2013;27:e348.
  12. Shankar N, et al. LVAD implant as a bridge to heart transplantation is associated with allosensitization as measured by single antigen bead assay. Transplantation. 2013;96:324.
  13. Barbara DW, et al. The perioperative management of patients undergoing combined heart-liver transplantation. Transplantation. 2015;99:139.
  14. Burkhart HM, et al. Regenerative therapy for hypoplastic left heart syndrome: First report of intraoperative intramyocardial injection of autologous umbilical-cord blood-derived cells. Journal of Thoracic and Cardiovascular Surgery. 2015;149:e35. http://www.sciencedirect.com/science/article/pii/S002252231401602X. Accessed May 5, 2016.
  15. Pundi KN, et al. 40-year follow-up after the Fontan operation: Long-term outcomes of 1,052 patients. Journal of the American College of Cardiology. 2015;66:1700.
  16. Rosenbaum AN, et al. Current indications, strategies and outcomes with cardiac transplantation for cardiac amyloidosis and sarcoidosis. Current Opinion in Organ Transplantation. 2015;20:584.
  17. Grupper A, et al. Increased risk of antibody mediated rejection and subsequent allograft vasculopathy in women post cardiac transplantation. Journal of Women's Health. 2015;24:A-16.
  18. Rosenbaum AN, et al. Association between early cardiac rehabilitation and long-term survival in cardiac transplant recipients. Mayo Clinic Proceedings. 2016;91:149.
  19. Medical practice report: Heart transplant. Press Ganey. http://www.pressganey.com/. Accessed May 24, 2016.
  20. Khandhar SJ, et al. Optical coherence tomography for characterization of cardiac allograft vasculopathy after heart transplantation. Journal of Heart and Lung Transplantation. 2013;32:596.
  21. Mayo Clinic Children's Center becomes first accredited pediatric heart failure institute in Minnesota and fourth in the nation (news release). http://www.evaluategroup.com/Universal/View.aspx?type=Story&id=458981. Accessed June 27, 2016.
  22. Doctors name America's top residency programs (news release). U.S. News & World Report. http://health.usnews.com/health-news/top-doctors/articles/2014/02/20/doctors-name-americas-top-residency-programs. Accessed June 27, 2016.
  23. Centers of excellence. Extracorporeal Life Support Organization. https://www.elso.org/Excellence/CentersofExcellence.aspx. Accessed June 27, 2016.
  24. Heilman RL (expert opinion). Mayo Clinic, Phoenix/Scottsdale, Ariz. June 24, 2016.