Print DiagnosisYour health care provider will usually ask you about your symptoms and discuss your personal medical history to diagnose idiopathic hypersomnia. You'll also likely have a physical exam. You may have several tests to either diagnose your condition or rule out other conditions that may be causing your symptoms. It's important to discuss your family history and what medicines you're taking. For a diagnosis of idiopathic hypersomnia, you must have experienced daily excessive sleepiness for at least three months. These may also help diagnose idiopathic hypersomnia: Epworth Sleepiness Scale. Your health care provider may ask you to rate your sleepiness with this tool to help determine how sleep affects your daily life. Sleep diary. Your provider may ask you to keep a sleep diary. You log your daily sleep and wake times to help show your sleep patterns and how much you sleep. Polysomnogram. In this test, you stay in a sleep center overnight. A polysomnogram monitors your brain activity, eye movements, leg movements, heart rate, breathing functions and oxygen levels as you sleep. Multiple sleep latency test. You are given multiple daytime nap opportunities and during these naps, measurements show the types and stages of sleep you go through. This test is generally conducted the day after a polysomnogram. Care at Mayo Clinic Our caring team of Mayo Clinic experts can help you with your idiopathic hypersomnia-related health concerns Start Here TreatmentBecause the cause of idiopathic hypersomnia isn't known, the treatment is aimed at easing symptoms. Stimulant medication, such as modafinil (Provigil, Alertec), might be prescribed to help you stay awake during the day. Possible side effects of modafinil are headaches, dry mouth, nausea, diarrhea, loss of appetite and weight loss. Other medicines suggested by the American Academy of Sleep Medicine are sodium oxybate (Xyrem), clarithromycin (Biaxin XL, Klaricid) and methylphenidate (Quillivant XR, Daytrana, QuilliChew ER). Recently, a drug containing lower-sodium oxybate (Xywav) was approved by the U.S. Food and Drug Administration for the treatment of idiopathic hypersomnia in adults. In addition, your health care provider might recommend that you develop a regular nighttime sleep schedule and avoid alcohol and medications that can affect your sleep. By Mayo Clinic Staff Idiopathic hypersomnia care at Mayo Clinic Request an appointment Symptoms & causesDoctors & departments Oct. 07, 2022 Print Show references Chervin RD. Idiopathic hypersomnia. https://www.uptodate.com/contents/search. Accessed May 12,2022. Idiopathic hypersomnia. Genetic and Rare Diseases Information Center. https://rarediseases.info.nih.gov/diseases/8737/idiopathic-hypersomnia. Accessed May 12, 2022. Trotti LM, et al. Idiopathic hypersomnia and other hypersomnia syndromes. Neurotherapeutics.2021; doi:10.1007/s13311-020-00919-1. Dauvilliers Y, et al. Safety and efficacy of lower-sodium oxybate in adults with idiopathic hypersomnia: A phase 3, placebo-controlled, double-blind, randomized withdrawal study. Lancet Neurology. 2022; doi:10.1016/S1474-4422(21)00368-9. Littner MR, et al. Practice parameters for clinical use of the multiple sleep latency test and the maintenance of wakefulness test. Sleep. 2005; doi:10.1093/sleep/28.1.113. Inoue Y, et al. Efficacy and safety of modafinil in patients with idiopathic hypersomnia without long sleep time: A multicenter, randomized, double-blind, placebo-controlled, parallel-group comparison study. Sleep. 2021; doi:10.1016/j.sleep.2021.01.018. Sowa NA. Idiopathic hypersomnia and hypersomnolence disorder: A systematic review of the literature. Psychosomatics. 2016; doi:10.1016/j.psym.2015.12.006. Saini P, et al. Hypersomnia evaluation, treatment and social and economic aspects. Sleep Medicine Clinics. 2017; doi:10.1016/j.jsmc.2016.10.013. Nguyen H. AllScripts EPSi. Mayo Clinic. April 20, 2022. Maski K, et al. Treatment of central disorders of hypersomnolence: An American Academy of Sleep Medicine clinical practice guideline. Journal of Clinical Sleep Medicine. 2021; doi:10.5664/jcsm.9328. Related Products & Services A Book: Mayo Clinic Family Health Book Newsletter: Mayo Clinic Health Letter — Digital Edition Show more products and services from Mayo Clinic Idiopathic hypersomniaSymptoms&causesDiagnosis&treatmentDoctors&departmentsCare atMayoClinic Advertisement Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. Advertising & Sponsorship Policy Opportunities Ad Choices Mayo Clinic Press Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. 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