Print Departments and specialties Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery. Departments that treat this condition Cancer Care at Mayo Clinic Early-Onset and Hereditary GI Cancers Program Gastroenterology and Hepatology Hepatobiliary and Pancreas Surgery in Jacksonville Hepatobiliary and Pancreas Surgery in Rochester Hepatobiliary Clinic Laboratory Medicine and Pathology Liver Transplant Program Oncology (Medical) Proton Beam Therapy Program Radiation Oncology Radiology Surgery Surgical Oncology and Endocrine Surgery in Arizona Transplant Center Areas that research this condition Radiology Research Research Bile duct cancer researchers Doctors and scientists work together to develop new options for people with bile duct cancer. Researchers at Mayo Clinic are studying new ways to diagnose and treat hilar cholangiocarcinoma. This research is conducted as part of the Division of Gastroenterology and Hepatology in coordination with Mayo Clinic Cancer Center. Mayo Clinic Cancer Center receives funding from the National Cancer Institute (NCI) and is an NCI-designated comprehensive cancer center — recognition for an institution's scientific excellence and multidisciplinary resources focused on cancer prevention, diagnosis and treatment. Areas of research include: Studying the association of aspirin and statin medicines with a reduced risk of cholangiocarcinoma. Investigating the molecular genetics of tumors and identifying biomarkers, which may aid in early diagnosis or lead to new targeted therapies. Doing clinical trials for new targeted therapies. These trials are possible because of Mayo Clinic's high patient volume for primary sclerosing cholangitis and bile duct cancer. Expanding surgical options and refining techniques, including vessel and bile duct reconstruction, to widen the number of people who may qualify for curative approaches. Proving that the biomarker CA 19-9 is useful for staging cholangiocarcinoma and understanding the prognosis for people with the disease. PublicationsSee a list of publications about cholangiocarcinoma by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine. Research Profiles Edit search filters close Narrow your search By location Arizona Florida Minnesota View all View all physicians • All Locations Borad, Mitesh J. M.D. Arizona Gores, Gregory J. M.D. Minnesota Graham, Rondell P. M.B.B.S. Minnesota Haddock, Michael G. M.D. Minnesota Ilyas, Sumera I. M.B.B.S. Minnesota LaRusso, Nicholas F. M.D. Minnesota Patel, Tushar C. M.B., Ch.B. Florida Que, Florencia G. M.D. Minnesota Roberts, Lewis R. M.B., Ch.B., Ph.D. Minnesota Smoot, Rory L. M.D. Minnesota Truty, Mark J. M.D., M.S. Minnesota By Mayo Clinic Staff Hilar cholangiocarcinoma care at Mayo Clinic Request an appointment Survival ratesCare at Mayo Clinic Jan. 20, 2026 Print Living with hilar cholangiocarcinoma? Connect with others like you for support and answers to your questions in the Sarcoma support group on Mayo Clinic Connect, a patient community. Sarcoma Discussions What treatments did you have for angiosarcoma? 10 Replies Tue, Sep 01, 2026 chevron-right Diagnosed with sarcoma? Let's share 1100 Replies Mon, Aug 31, 2026 chevron-right FS-DFSP (Fibrosarcomatous dermatofibrosarcoma): Anyone else? 55 Replies Mon, Aug 31, 2026 chevron-right See more discussions Related Cholangiocarcinoma Associated Procedures Biological therapy for cancer Chemotherapy CT scan ERCP Liver function tests Liver transplant MRI Palliative care Radiation therapy Radiofrequency ablation for cancer Ultrasound Show more associated procedures Products & Services A Book: Mayo Clinic Family Health Book Newsletter: Mayo Clinic Health Letter — Digital Edition Show more products and services from Mayo Clinic Hilar cholangiocarcinomaSymptoms&causesDiagnosis&treatmentStagesSurvivalratesDoctors&departmentsCare atMayoClinic Research: It's all about patients Show transcript for video Research: It's all about patients [MUSIC PLAYING] Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight. CON-20202299 Diseases & Conditions Hilar cholangiocarcinoma