Overview

Hepatopulmonary (hep-uh-toe-POOL-moe-nar-e) syndrome is an uncommon condition that affects the lungs of people with advanced liver disease. Hepatopulmonary syndrome is caused by blood vessels in the lungs expanding (dilating) and increasing in number, making it hard for red blood cells to properly absorb oxygen. This leaves the lungs unable to deliver adequate amounts of oxygen to the body, which leads to low oxygen levels (hypoxemia).

Exactly how the liver disease is linked to the lung condition isn't yet clear. A liver transplant is the only cure for the syndrome.

Hepatopulmonary syndrome care at Mayo Clinic

Feb. 09, 2018
References
  1. Ferri FF. Hepatopulmonary syndrome. In: Ferri's Clinical Advisor 2018. Philadelphia, Pa.: Elsevier; 2018. https://www.clinicalkey.com. Accessed Dec. 20, 2017.
  2. Lange PA, et al. Hepatopulmonary syndrome: Prevalence, causes, clinical manifestations and diagnosis. https://www.uptodate.com/contents/search. Accessed Dec. 18, 2017.
  3. Koch DG. Hepatopulmonary syndrome. Clinical Liver Disease. 2014;18:407.
  4. Lange PA, et al. Hepatopulmonary syndrome: Natural history, treatment and outcomes. https://www.uptodate.com/contents/search. Accessed Dec. 18, 2017.
  5. Rochester Methodist Hospital (Mayo Clinic). Scientific Registry of Transplant Recipients. https://www.srtr.org/transplant-centers/rochester-methodist-hospital-mayo-clinic-mnmc/?organ=liver&recipientType=adult&donorType. Accessed Dec. 19, 2017.
  6. Mayo Clinic Florida. Scientific Registry of Transplant Recipients. https://www.srtr.org/transplant-centers/mayo-clinic-florida-flsl/?organ=liver&recipientType=adult&donorType. Accessed Dec. 19, 2017.
  7. Mayo Clinic Hospital (AZMZ). Scientific Registry of Transplant Recipients. https://www.srtr.org/transplant-centers/mayo-clinic-hospital-azmc/?organ=liver&recipientType=adult&donorType. Accessed Dec. 19, 2017.