These tests can help determine if you have hepatopulmonary syndrome:

  • Pulse oximetry. In pulse oximetry, a sensor attached to your finger or ear uses light to determine how much oxygen is in your blood.
  • Chest imaging. X-rays, computerized tomography (CT) scanning or echocardiogram imaging can help rule out other heart or lungs conditions.


Supplemental oxygen therapy is the main treatment for shortness of breath caused by low oxygen levels in the blood. A liver transplant is the only cure for hepatopulmonary syndrome.

Clinical trials

Explore Mayo Clinic studies testing new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition.

Hepatopulmonary syndrome care at Mayo Clinic

Jan. 06, 2022
  1. Kellerman RD, et al. Cirrhosis. In: Conn's Current Therapy 2019. Elsevier; 2019. https://www.clinicalkey.com. Accessed Dec. 9, 2019.
  2. Ferri FF. Hepatopulmonary syndrome. In: Ferri's Clinical Advisor 2020. Elsevier; 2020. https://www.clinicalkey.com. Accessed Dec. 9, 2019.
  3. Hepatopulmonary syndrome. National Organization for Rare Disorders. https://rarediseases.org/rare-diseases/hepatopulmonary-syndrome/. Accessed Dec. 9, 2019.
  4. Hepatopulmonary syndrome. Merck Manual Professional Version. https://www.merckmanuals.com/professional/pulmonary-disorders/pulmonary-hypertension/hepatopulmonary-syndrome#. Accessed Dec. 9, 2019.
  5. Brown AY. Allscripts EPSi. Mayo Clinic. Nov. 14, 2019.


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