Research

Mayo Clinic researchers are continually developing improved screening methods and treatments for hereditary polyp disorders, such as FAP, and colorectal cancer. Mayo maintains a Colon Cancer Family Registry to help keep you informed of new screening techniques and procedures. Mayo scientists are working to discover more about the genetic basis of FAP and other hereditary polyp disorders and to clinically translate those genetic findings to medical care. Surgeons also are working to improve treatments, such as laparoscopic techniques for colorectal procedures.

Publications

See a list of publications about familial adenomatous polyposis by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles

June 30, 2021

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  1. Chung DC, et al. Clinical manifestations and diagnosis of familial adenomatous polyposis. https://www.uptodate.com/contents/search. Accessed June 4, 2018.
  2. Familial adenomatous polyposis. Cancer.Net. http://www.cancer.net/cancer-types/familial-adenomatous-polyposis. Accessed June 4, 2018.
  3. Kanth P, et al. Hereditary colorectal polyposis and cancer syndromes: A primer on diagnosis and management. American Journal of Gastroenterology. 2017; 112:1509.
  4. Ferri FF. Familial adenomatous polyposis and Gardner's syndrome. In: Ferri's Clinical Advisor 2019. Philadelphia, Pa.: Elsevier; 2019. https://www.clinicalkey.com. Accessed June 4, 2018.
  5. Ravi V, et al. Desmoid tumors: Epidemiology, risk factors, molecular pathogenesis, clinical presentation, diagnosis, and local therapy. https://www.uptodate.com/contents/search. Accessed June 4, 2018.
  6. Chung DC, et al. Familial adenomatous polyposis: Screening and management of patients and families. https://www.uptodate.com/contents/search. Accessed June 4, 2018.
  7. Genetic and Rare Diseases Information Center (GARD). Familial adenomatous polyposis. https://rarediseases.info.nih.gov/diseases/6408/familial-adenomatous-polyposis. Accessed June 4, 2018.
  8. Chintalacheruvu LM, et al. Major hereditary gastrointestinal cancer syndromes: A narrative review. Journal of Gastrointestinal Liver Disease. 2017;26:157.
  9. Attenuated familial adenomatous polyposis. Genetic and Rare Diseases Information Center (GARD). https://rarediseases.info.nih.gov/diseases/8532/attenuated-familial-adenomatous-polyposis. Accessed June 4, 2018.
  10. Syngal S, et al. ACG clinical guideline: Genetic testing and management of hereditary gastrointestinal cancer syndromes. American Journal of Gastroenterology. 2015;110: 223.
  11. Brown AY. Allscripts EPSi. Mayo Clinic, Rochester, Minn. March 28, 2018.
  12. Ravi V, et al. Desmoid tumors: Systemic therapy. https://www.uptodate.com/contents/search. Accessed June 4, 2018.
  13. Picco MF (expert opinion). Mayo Clinic, Jacksonville, Fla. July 1, 2018.