The Transplant Center includes transplant services and research at Mayo Clinic's campuses in Arizona, Florida and Minnesota. In clinical and basic research, researchers study improved surgical procedures, develop new anti-rejection medications (immunosuppressive medications), study how to improve outcomes and care for people who need transplants. Research also focuses on finding alternative therapies for people who may not need a transplant.

Mayo Clinic researchers study several areas of transplant research, including:

  • Heart and lung transplant. In heart and lung transplant research, researchers study new surgical procedures, outcomes after transplants and other areas. Researchers also study other potential treatment options, including transplanting living organs from one species to another (xenotransplantation) and gene therapy.
  • Liver transplant. In liver transplant research, researchers study how to improve outcomes and care for people who need a liver transplant. Researchers also study hepatitis C and B, immunosuppressive medications, bioartificial liver technology, and other areas.
  • Kidney, pancreas and islet cell transplant. Researchers study living-donor kidney transplants, kidney transplants between incompatible blood types (ABO incompatible kidney transplants), kidney transplants for recipients whose protein substances (antibodies) react against their donors' cells (positive crossmatch kidney transplants), and immunosuppressive medications. In addition, Mayo transplant researchers study what happens to kidneys years after transplant to try to determine why some kidneys fail and others last longer. Mayo Clinic staff has developed innovations to increase the utilization of deceased-donor organs to increase transplant rate for people waiting for kidney transplantation.
  • Blood and marrow transplant. In blood and marrow transplant, researchers study how to improve your immune system's function, how to improve outcomes, and how to reduce recurrence of your condition after a blood and marrow transplant.

Transplant research articles


See a list of publications by Mayo Clinic physicians on PubMed, a service of the National Library of Medicine.

Read more about transplant laboratories and programs:

Lowering rejection in organ transplant

Watch Mark Stegall, M.D., and Richard Daly, M.D., discuss lowering rejection risk in organ transplants.

Research Profiles

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Nov. 19, 2020