Imaging is key to diagnosing and treating pain conditions. Collaborative review of radiographic images

Pain medicine specialists review complex imaging before an advanced pain procedure.

Mayo Clinic's pain medicine specialists are experts in helping adults and children with a wide range of painful disorders. They listen to your concerns and develop an individualized treatment plan to make sure you get the right therapy when you need it.

For people with complicated medical histories and multidimensional pain syndromes, treatment may be multifaceted and require complex interventions. Mayo Clinic's dedicated team of pain medicine experts carry out tens of thousands of procedures and surgeries each year. These doctors are experienced with the full range of options, including drug treatment, pain rehabilitation and management, injection therapies, and implantable pain management devices — such as spinal cord stimulators. Pediatric pain rehabilitation programs are offered at Mayo Clinic's campus in Minnesota.

A team approach focused on you

Pain medicine doctors do hospital rounds. A team approach to pain care

Pain medicine doctors work together to determine which treatment would be best in your situation.

Your doctor talks with you and answers your questions. He or she may consult with specialists in anesthesiology, neurology, neurosurgery, orthopedic surgery, sports medicine, physical medicine and rehabilitation, psychiatry and psychology, or other areas to determine the best treatment for you. Your care team may also include physician assistants, nurse practitioners, registered nurses and clinical assistants — all working together in a focused effort on your treatment plan.

Mayo Clinic's multidisciplinary approach means your test results are available quickly and appointments are scheduled in coordination. What might take months elsewhere can often be done in days here.

Advanced diagnosis and treatment

Doctors discuss their plan before performing an injection for pain. Pain medicine procedure

A medical team discusses its approach to a pain procedure before starting.

The pain medicine team at Mayo Clinic includes doctors with advanced training (fellowship-trained experts) in anesthesiology, physical medicine and rehabilitation and neurology. Some have subspecialty expertise in ultrasonography, fluoroscopy, facial pain, neurostimulation, palliative care, peripheral nerve stimulation and regenerative medicine.

Mayo Clinic pain medicine doctors offer the complete spectrum of advanced pain management therapies. These include the latest in interventional and injection therapies, medication evaluation and recommendation, rehabilitative approaches, implantable pain management devices, and regenerative therapies, such as platelet-rich plasma and stem cell injections.

The combination of care providers from different backgrounds and access to a wide variety of treatment options ensure you receive comprehensive, innovative, supportive care and a treatment plan tailored to you.

Applying research to improve care

Mayo Clinic doctors and scientists seek new knowledge to improve therapies — including regenerative medicine approaches — for people with chronic pain conditions. For example, one research group is looking at how stem cells can be used to repair damaged tissue in the disks of the spine. Because Mayo Clinic's pain medicine doctors are involved in research, they offer advanced therapies that are available at very few medical centers.

In addition, pain medicine doctors at Mayo Clinic are committed to conducting clinical research to improve diagnosis and treatment options for people with painful disorders. Talk with your doctor about innovative clinical trials that you might be eligible for.

Mayo Clinic in Rochester, Minnesota, Mayo Clinic in Phoenix/Scottsdale, Arizona, and Mayo Clinic in Jacksonville, Florida, are ranked among the Best Hospitals for neurology and neurosurgery in the U.S. News & World Report Best Hospitals rankings.

Mayo Clinic in Rochester, Minnesota, Mayo Clinic in Jacksonville, Florida, and Mayo Clinic in Phoenix/Scottsdale, Arizona, are ranked among the Best Hospitals for cancer care by U.S. News & World Report. Mayo Clinic Children's Center in Rochester is ranked the No. 1 hospital in Minnesota, and the five-state region of Iowa, Minnesota, North Dakota, South Dakota and Wisconsin, according to U.S. News & World Report's 2023–2024 "Best Children's Hospitals" rankings.



  • Mayo Clinic Pain Medicine
  • 5881 E. Mayo Blvd.
    Phoenix, AZ 85054
  • Phone: 480-301-8394


  • Mayo Clinic Pain Medicine
  • 4500 San Pablo Road
    Jacksonville, FL 32224
  • Phone: 904-953-0858


  • Mayo Clinic Pain Medicine
  • 200 First St. SW
    Rochester, MN 55905
  • Phone: 507-284-2511
Jan. 10, 2023