Orthopedic Surgery

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. 3D US Imaging of Acute Nerve Root Avulsions in Injuries of the Brachial Plexus

   Jacksonville, Fla.

   The purpose of this study is to address a knowledge gap. Early diagnosis of nerve root avulsion injuries following brachial plexus trauma remain a barrier to the early treatment of these complex injuries.  Traditionally, an observation period of 6 months following brachial plexus injuries has been utilized to allow for reinnervation.  Reinnervation is not possible in the setting of nerve root avulsion from the spinal cord and waiting for reinnervation in this setting unnecessarily delays treatment and potentially compromises outcome.  Having the ability to provide a real time evaluation of nerve root integrity would obviate the need of other more expensive and complex advanced imaging such as CT/myelography, currently considered the good standard.

2. A Study to Assess the Effect of Radial Deviation on the Pronated Grip

   Rochester, Minn.

   The purpose of this study is to describe a practical and reproducible radiographic view that can be used in the work-up of ulnocarpal impaction.

3. Outcome of Capsular Release for Elbow Contracture

   Rochester, Minn.

   The purpose of this study is to assess the outcome and complications of capsular release for elbow contractures.

    

4. The Effects of Prophylactic Limited Palmar Fasciectomy on Surgical Outcomes and Scarring

   Rochester, Minn.

   Research is instrumental for improving medical care and the patient experience. Finding new surgical techniques can create better outcomes and minimize recovery time and complications for patients. Some patients undergoing trigger finger surgery with a pre-existing Dupuytren's cord may develop a thickened surgical scar after surgery, which can cause discomfort, difficulty with moving or using, and other complications in the affected finger(s) or hand. The investigator is investigating a surgical technique to minimize these potential complications and scarring after surgery. Subjects are being asked to take part in this research study because they have been diagnosed with trigger finger and pretendinous Dupuytren's cord and have decided to undergo surgery rather than try medical treatment.

5. Genetic Analysis of Disorders of Fibrosis

   Rochester, Minn.

   The specific aim of this protocol is to identify microRNAs that are differentially expressed between diseased fibrotic tissue (dupuytrens disease and plantar fibromatosis) and normal fibrotic tissue.

6. Multicenter Prospective Cohort Study on Current Treatments of Legg-Calvé-Perthes Disease

   Rochester, Minn.

   Legg-Calvé-Perthes disease is a childhood hip disorder which is common enough to be a significant public health problem (affects 1 in 740 boys between ages 0-14), but uncommon enough to have a sufficient number of patients from a single institution to perform a definitive prospective study comparing the results of current treatments. The present study will establish a database of prospectively identified patients with Legg-Calvé-Perthes (LCP) Disease and collect information regarding their presentation, treatment, and outcomes in the course of receiving currently available treatments. This study seeks to compare the outcomes of current treatments in the management of different age groups (ages 1-6, 6-8, 8-11, >11) of patients with Perthes disease at two- and five-year followup and at skeletal maturity. For each age group, two to three common treatment regimens currently used by practicing pediatric orthopaedic surgeons will be compared. The intervention a patient receives is determined through physician treatment expertise, and is not pre-determined by the study.

7. Shoulder Arthroscopy: Functional and Clinical Outcomes

   Rochester, Minn.

   The purpose of this study is to evaluate the clinical and functional outcomes of patients undergoing arthroscopic shoulder surgery.

8. A Study of Performance of a New Investigational Prosthesis Design and Explore How Mimicking the Human Ankle May Enhance Maneuverability of Walking

   Rochester, Minn.

   The purpose of this study is to see how you walk with an investigational new type of ankle-foot prosthesis that has been developed, which can allow motion in more than one direction.

9. A Study to Compare 3- and 4-Part Proximal Humerus Fractures Undergoing Elected Nonoperative vs. Operative Management

   Rochester, Minn.

   The purpose of this study is to compare validated clinical and functional outcomes between patients who acutely present with 3- and 4-part Proximal Humerus Fractures (PHFs) treated nonoperatively or with rTSA. We hypothesize that in displaced 3- and 4-part proximal humerus fractures, rTSA will have better pain relief and functional outcomes than nonoperative treatment.

    

10. A Study to Evaluate A Patient's Perception of Indwelling Foley Catheters Following Total Hip or Total Knee Arthroplasty

    Jacksonville, Fla.

    The purpose of this study is to evaluate the orthopedic patients’ perspective on the use of indwelling foley catheters.