Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people. In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals, or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

U.S. patients

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Telephone requests

Mayo Clinic's campus in Phoenix/Scottsdale, Arizona

Central Appointment Office

  1. 480-301-8484
  2. 8 a.m. to 5 p.m.
  3. Mountain time
  4. Monday through Friday
Mayo Clinic's campus in Jacksonville, Florida

Ask your primary care provider to contact Mayo Clinic to schedule an appointment.

Mayo Clinic's campus in Rochester, Minnesota

Nicotine Dependence Center

  1. 507-266-1930 (toll-free)
  2. 800-344-5984 (toll-free)
  3. 7 a.m. to 5 p.m.
  4. Central time
  5. Monday through Friday

Nicotine Research Program

  1. 800-848-7853 (toll-free)
  2. Fax: 507-266-7900
  3. Email:

People who want to stop using tobacco find the care they need at Mayo Clinic, where specialists in smoking cessation support them as they try to live tobacco- and nicotine-free. The Mayo Clinic team of tobacco treatment specialists offers a range of treatment options, including counseling, medication, behavioral therapies, a residential smoking cessation program and relapse prevention strategies.

The Mayo Clinic Nicotine Dependence Center at Mayo Clinic's campus in Minnesota was one of the first centers in the United States to focus exclusively on treatments for tobacco dependence. This model of care has now become the standard in many medical centers.

The treatment team at the center offers you support and works with you to help develop the motivation and skills needed to stop using tobacco.

  • Experience. Each year thousands of people benefit from the stop-smoking services at Mayo Clinic's campuses in Arizona, Florida and Minnesota.
  • Treatment offerings. Mayo Clinic's campuses in Arizona, Florida and Minnesota offer a variety of stop-smoking treatment options, including individualized evaluation and planning, ongoing in-person support by telephone, web or text, and, in Minnesota, an intensive residential treatment program.
  • Comprehensive, evidence-based care. Mayo Clinic's nicotine dependence treatment services are supervised by doctors. That means all aspects of your condition are considered in the treatment process. Your care team makes sure that your nicotine dependence treatment is coordinated with care you are receiving for other medical conditions, when necessary.
  • Latest research. Mayo Clinic nicotine dependence researchers have conducted clinical trials of drugs that help people quit tobacco. They also research behavior therapy, treatment outcomes, causes of nicotine dependence, cost-effectiveness of treatment, and integrating best practices for tobacco treatment into health care systems.
  • Educational opportunities. The Nicotine Dependence Center Education Program offers tobacco education for health care professionals. Offerings include an annual Tobacco Dependence Treatment Conference, tobacco treatment specialist certification training, patient intervention materials, distance learning opportunities and customized workshops. Some education programs can also be offered in your community.

Read more about nicotine dependence and stop-smoking services.

Mayo Clinic offers the following treatment options for people who want to break a nicotine addiction or stop smoking. Your treatment team can help you in changing thoughts, behaviors and habits around the use of nicotine. Tobacco use is a cause of many health conditions, including heart (cardiovascular) disease, 14 types of cancer and respiratory illness. Treating nicotine dependence is an important factor in treatment of these and other conditions. Stopping smoking will significantly improve surgical outcomes.

Availability of some services varies among Mayo Clinic locations. Please confirm when you request an appointment.

  • Individual consultation and customized treatment plan. Your treatment begins with a one-on-one consultation at Mayo Clinic. Then many people follow up with one or more individual sessions, which can be done in person or virtually by video or phone. These sessions can help you stay motivated, avoid or address relapse, and gain confidence in your ability to stay free of tobacco or e-cigarettes.
  • Outpatient counseling. Your first meeting is a comprehensive consultation with a tobacco treatment specialist (TTS). You do not need to be ready to quit to benefit from this meeting. The TTS works with you to understand your short- and long-term goals for tobacco and nicotine use and for quitting in a way that works for you when you are ready. The TTS will help you develop a plan that can work for you. Depending on your situation, the TTS may also work with a supervising doctor to prescribe a medication plan. And your tobacco treatment team coordinates with any other care providers you have at Mayo Clinic to ensure your tobacco treatment plan fits with your overall care at the clinic.
  • Residential smoking cessation program. This intensive smoking rehab program includes daily visits to Mayo Clinic for individual and group counseling led by our team of certified TTS counselors. It also includes medical supervision by tobacco treatment experts, educational sessions and supervised aftercare.
  • Bedside treatment during hospitalization. If you're hospitalized, a TTS may visit you at your bedside. The specialist can help make sure you get medications helpful in managing nicotine withdrawal and cravings while you're in the hospital. And the specialist may also talk with you about your intentions for nicotine and tobacco use and help you develop a plan to achieve your goals after you leave the hospital.

Mayo Clinic provides top-quality, evidence-based care for tobacco and nicotine dependence. Its nonjudgmental and supportive specialists help you develop a plan that gives you the best chance of success. When you're ready to stop, the right treatment approach can make it easier than you might think.

If you're not ready to quit, you can still benefit from a visit with a tobacco treatment specialist to learn more about why stopping tobacco use can be difficult and develop a plan so that you can succeed — when you're ready.

Availability of some services varies among Mayo Clinic locations. For example, the residential treatment program is part of the Nicotine Dependence Center at Mayo Clinic's campus in Minnesota. Please confirm when you request an appointment.

Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery.

Find doctors and medical staff:


Allied health professionals

  • Jennifer M. Burden, Ph.D., C.T.T.S.
  • Barbara Dallavalle, M.A., C.T.T.S.
  • Sarah E. Huiskes, M.A., L.I.C.S.W., M.S.W
  • Heather L. Kraling-Coons, M.A., C.T.T.S.
  • Molly J. Leis, M.S., L.A.D.C., C.T.T.S.
  • Dhivyaa A. Manickam, M.A., C.T.T.S.
  • Timothy J. Milbrandt, M.S, C.T.T.S.
  • Ann M. Thompson, APRN, C.N.P., M.S.N.
  • Kathleen (Kathy) K. Zarling, M.S., C.T.T.S.

Mayo Clinic has major campuses in Phoenix and Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota. The Mayo Clinic Health System has dozens of locations in several states.

For more information on visiting Mayo Clinic, choose your location below:

Mayo Clinic doctors and scientists do extensive research to refine and improve treatment approaches to smoking cessation.

Areas of investigation include:

  • The effects of e-cigarettes on the heart
  • Success rates of various treatment approaches
  • Models for integrating tobacco treatment into clinical practice
  • Dosage levels for nicotine replacement medications
  • New medications that offer relief from withdrawal symptoms
  • The impact of tobacco and nicotine on surgical outcomes
  • Treatment outcomes of cessation programs for special patient populations

Mayo Clinic nicotine dependence experts advance care of people who want to become tobacco free or to stop e-cigarette use by integrating the latest research into treatment options. Since opening in 1988, the Nicotine Dependence Center at Mayo Clinic's campus in Minnesota has made many notable contributions to the field of addiction research and tobacco-dependence interventions.

Programs and centers


See a list of publications about nicotine dependence by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Our patients tell us that the quality of their interactions, our attention to detail and the efficiency of their visits mean health care like they've never experienced. See the stories of satisfied Mayo Clinic patients.

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people.

In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Learn more about appointments at Mayo Clinic.

Please contact your insurance company to verify medical coverage and to obtain any needed authorization prior to your visit. Often, your insurer's customer service number is printed on the back of your insurance card.