Cardiovascular Medicine

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. A Study To Evaluate The Influence Of Pulse Electromagnetic Field Therapy On Myocardial Ischemia

   Scottsdale/Phoenix, Ariz., Rochester, Minn.

   The purpose of this study is to determine the impact of pulse electromagnetic field (PEMF) therapy using the Bioboosti device (Biomobie Regenerative Medicine Company) and therapeutic protocol on cardiac ischemia in patients with coronary artery disease as quantified using an assessment of myocardial blood flow using 13N-ammonia myocardial perfusion positron emission tomography (PET) scanning to quantify blood flow during chemical induced stress.

2. Identification of Novel Genetic Variants and Biomarkers of Disease Progression in Arrhythmogenic Cardiomyopathy

   Rochester, Minn.

   The purpose of this study is to identify hereditary causes of cardiomyopathy.

3. Mayo Clinic Cardiovascular Disease Biobank

   Rochester, Minn.

   The purpose of this study is to determine the innate immune, cell death and oxidative stress changes in the myocardium, and aorta of patients with heart failure compared to patients with normal hearts.

4. Genotype-Phenotype Correlation in Cardiovascular Disease

   Rochester, Minn.

   This research study is being done to help characterize cardiovascular disease and improve diagnostic tests.

   OBJECTIVES

   1. To understand the pathogenesis, molecular mechanisms, and disease progression of heritable cardiovascular disease

   2. To evaluate the incidence of occult heritable cardiovascular disease in various populations.

   3. To correlate imaging and pathological phenotype with genotype to the ends described above.

5. A Study to Assess the Role of Biomarkers in Risk Stratification in Adults with Congenital Heart Disease

   Rochester, Minn.

   The purporse of this study is to determine if biomarker assay obtained at baseline can predict future risk of cardiovascular adverse events, and to  determine if temporal changes in biomarker levels can provide a better risk prediction compared to biomarker assay obtained at baseline.

6. Unipedal Stance Time With Frailty Scores in Transcatheter Aortic Valve Replacement Patients

   Rochester, Minn.

   The objective of this study is to compare the unipedal stance time with serum albumin, 5-meter walk test and KATZ questionnaire findings as frailty scores in transcatheter aortic valve replacement (TAVR) patients.

    

    

7. Echocardiographic Measures of Pulmonary Vascular Distensibility and Effects on Lung Diffusing Capacity

   Rochester, Minn.

   The purpose of this study is to determine if the change in pulmonary vascular compliance with positional changes (upright, supine, and Trendelenburg position) is different in younger versus older individuals.

8. A Study to Evaluate Potential Myocardial Injury Following Magnetic Resonance Imaging (MRI)

   Rochester, Minn.

   The purpose of this study is to prospectively determine if magnetic resonance imaging (MRI) in patients with cardiac implantable electronic devices (CIED) results in myocardial injury as assessed by changes in high sensitivity cardiac troponin T (hs-cTnT) assay. This will be done by comparing pre-and-post MRI hs-cTnT levels in these patients.

9. Surgeons As High-Performance Athletes

   Rochester, Minn.

   The purpose of this prospective observational study is to gather and evaluate the evidence for attending surgeons’ technical and tactical abilities and cognitive workload, during cardiac surgery.

10. ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™

    Rochester, Minn.

    To demonstrate non-inferiority of the Trilogy Transcatheter Heart Valve (THV) System compared with surgical aortic valve replacement (SAVR) for treatment of subjects with clinically significant native aortic regurgitation (AR)