Mayo Clinic's approach

The Transgender and Intersex Specialty Care Clinic (TISCC) at Mayo Clinic delivers integrated gender-affirming care that includes medical therapy, psychosocial care and surgery to transgender, gender diverse and intersex people. TISCC staff are committed to fostering an inclusive and safe environment that inspires hope and promotes health and well-being.

Learn more about Mayo Clinic's TISCC and the gender-affirming services it offers here.


TISCC's team collaborates across disciplines. It includes professionals from endocrinology, behavioral health, voice care, gynecology, urology and plastic surgery.

Each person is different. At Mayo Clinic, the TISCC team tailors care to your individual needs to ensure that your questions are answered, risks are minimized and your goals are achieved.

Advanced technology

Specialists at Mayo Clinic are committed to providing the latest and most comprehensive treatment options for transgender, gender diverse and intersex people, all in an inclusive and safe environment. Your team's advice about the best treatment for you is based on expert knowledge of and experience with a wide range of treatment options.

Expertise and rankings

At Mayo Clinic, having expertise from a range of specialists available in a single place, focused on your care, means that you're not just getting one opinion. You get comprehensive, integrated care tailored to your needs. That includes access to prompt test results, appointments scheduled in coordination and highly specialized experts working together to help you move forward to meet your goals.

Locations, travel and lodging

Mayo Clinic has major campuses in Phoenix and Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota. The Mayo Clinic Health System has dozens of locations in several states.

For more information on visiting Mayo Clinic, choose your location below:

Costs and insurance

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people.

In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Learn more about appointments at Mayo Clinic.

Please contact your insurance company to verify medical coverage and to obtain any needed authorization prior to your visit. Often, your insurer's customer service number is printed on the back of your insurance card.

More information about billing and insurance:

Mayo Clinic in Arizona, Florida and Minnesota

Mayo Clinic Health System

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May 14, 2024
  1. Coleman E, et al. Standards of Care for the Health of Transgender and Gender Diverse People. 8th version. International Journal of Transgender Health. 2022; doi:10.1080/26895269.2022.2100644.
  2. Shefcik G, et al. Voice-related experiences of nonbinary individuals (VENI) development and content validity. Journal of Voice. 2023; doi:10.1016/j.jvoice.2020.12.037.
  3. Tangpricha V, et al. Transgender women: Evaluation and management. Accessed Sept. 20, 2023.
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  6. Leung Y, et al. Voice, articulation and prosody contribute to listener perceptions of speaker gender: A systematic review and meta-analysis. Journal of Speech, Language and Hearing Research. 2018; doi:10.1044/2017_JSLHR-S-17-0067.
  7. Russell MR, et al. Transgender and nonbinary adolescents: The role of voice and communication therapy. Perspectives of the ASHA Special Interest Groups. 2019; doi:10.1044/2019_PERSP-19-00034.
  8. Health Education & Content Services. Gender-affirming voice therapy. Mayo Clinic; 2023.
  9. Bultynck C, et al. Thyroplasty type III to lower the vocal pitch in trans men. Otolaryngology – Head and Neck Surgery. 2021; doi:10.1177/0194599820937675.
  10. Orbelo DM (expert opinion). Mayo Clinic. Oct. 11, 2023.

Gender-affirming (transgender) voice therapy and surgery