Mayo Clinic's approach

Teamwork

The Transgender and Intersex Specialty Care Clinic (TISCC) provides integrated medical, psychosocial and surgical intervention to individuals with gender dysphoria or incongruence and to those with differences of sexual development, also called intersex. The team includes professionals from various specialties including endocrinology, pediatric endocrinology, social work, psychiatry, psychology, voice therapy, gynecology, urology and plastic surgery.

Mayo Clinic does not offer gender-affirming voice surgery at this time.

Treatments offered include:

  • Behavioral health assessment and management.
  • Gender-affirming hormone therapy.
  • Assistance with social and legal issues and referrals to community resources.
  • Fertility preservation.
  • Referrals for sexually transmitted infection screening and preexposure prophylaxis (PrEP).
  • Gender-affirming voice therapy.
  • Electrolysis and laser hair removal.
  • Hair transplant.
  • Gynecological care for trans men.
  • Chaplain services.
  • Preoperative and postoperative pelvic floor physical therapy.
  • Feminizing surgical procedures:
    • Breast augmentation.
    • Facial feminization.
    • Tracheal shave.
    • Body-contouring procedures.
    • Orchiectomy.
    • Vaginoplasty and labioplasty.
    • Robot-assisted peritoneal flap vaginoplasty.
  • Masculinizing surgical procedures:
    • Mastectomy with chest masculinization.
    • Body-contouring procedures.
    • Hysterectomy and oophorectomy.
    • Metoidioplasty.

Before you start treatment, you meet with at least one member of the TISCC medical team — a physician, a physician assistant or a nurse practitioner — and a member of the TISCC mental health team, such as a social worker, psychologist or psychiatrist. You have a complete medical evaluation to make sure that your treatment risks are identified and addressed. Before a surgical procedure, you are seen by the appropriate TISCC surgical team. Evaluation of your mental health ensures that any mood or mental health concerns are reasonably well managed before you start treatment.

Each person is different. Your Mayo Clinic healthcare team looks at your specific case in order to come up with the best recommendations for you. The team works with you during your treatment and makes sure your expectations are realistic. Your team wants to make sure your goals are being met, any risks are managed and your questions are answered.

Advanced technology

Mayo Clinic specialists are committed to providing the latest, most comprehensive treatment options for gender dysphoria. Your Mayo Clinic specialist's advice about the best treatment for you is based on expert knowledge of and experience with all treatment options.

Expertise and rankings

At Mayo Clinic, endocrinologists, psychiatrists, psychologists, nurse practitioners, social workers and surgeons work together to provide exactly the care you need.

Having all of this expertise in a single place, focused on you, means that you're not just getting one opinion — your care is discussed among the team, your test results are available quickly, your appointments are scheduled in coordination and highly specialized experts are all working together to determine what's best for you.

Locations, travel and lodging

Mayo Clinic has major campuses in Phoenix and Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota. The Mayo Clinic Health System has dozens of locations in several states.

For more information on visiting Mayo Clinic, choose your location below:

Costs and insurance

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people.

In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Learn more about appointments at Mayo Clinic.

Please contact your insurance company to verify medical coverage and to obtain any needed authorization prior to your visit. Often, your insurer's customer service number is printed on the back of your insurance card.

More information about billing and insurance:

Mayo Clinic in Arizona, Florida and Minnesota

Mayo Clinic Health System

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March 23, 2024
  1. Coleman E, et al. Standards of Care for the Health of Transgender and Gender Diverse People. 8th version. International Journal of Transgender Health. 2022; doi:10.1080/26895269.2022.2100644.
  2. Shefcik G, et al. Voice-related experiences of nonbinary individuals (VENI) development and content validity. Journal of Voice. 2023; doi:10.1016/j.jvoice.2020.12.037.
  3. Tangpricha V, et al. Transgender women: Evaluation and management. https://www.uptodate.com/contents/search. Accessed Sept. 20, 2023.
  4. Kim H-T. Vocal feminization for transgender women: Current strategies and patient perspectives. International Journal of General Medicine. 2020; doi:10.2147/IJGM.S205102.
  5. Yilmaz T, et al. Laser reduction glottoplasty for voice feminization: Experience on 28 patients. The Annals of Otology, Rhinology and Laryngology. 2021; doi:10.1177/0003489421993728.
  6. Leung Y, et al. Voice, articulation and prosody contribute to listener perceptions of speaker gender: A systematic review and meta-analysis. Journal of Speech, Language and Hearing Research. 2018; doi:10.1044/2017_JSLHR-S-17-0067.
  7. Russell MR, et al. Transgender and nonbinary adolescents: The role of voice and communication therapy. Perspectives of the ASHA Special Interest Groups. 2019; doi:10.1044/2019_PERSP-19-00034.
  8. Health Education & Content Services. Gender-affirming voice therapy. Mayo Clinic; 2023.
  9. Bultynck C, et al. Thyroplasty type III to lower the vocal pitch in trans men. Otolaryngology – Head and Neck Surgery. 2021; doi:10.1177/0194599820937675.
  10. Orbelo DM (expert opinion). Mayo Clinic. Oct. 11, 2023.

Gender-affirming (transgender) voice therapy and surgery