Mayo Clinic's approach


The Transgender and Intersex Specialty Care Clinic (TISCC) provides integrated medical, psychosocial and surgical intervention to individuals with gender dysphoria incongruence and to those with differences of sex development (intersex). The team includes providers from various specialties including endocrinology, pediatric endocrinology, social work, psychiatry, psychology, voice therapy, gynecology and plastic surgery.

Treatments offered include:

  • Mental health assessment and management
  • Hormone therapy and monitoring
  • Assistance with social and legal issues and referrals to community resources
  • Fertility preservation
  • Sexually transmitted infection screening and pre-exposure prophylaxis (PrEP)
  • Voice therapy
  • Electrolysis and laser hair removal
  • Hair transplant
  • Gynecological care for trans men
  • Chaplain services
  • Feminizing surgical procedures:
    • Top surgery for transgender women
    • Facial feminization
    • Body-contouring procedures
    • Orchiectomy
    • Tracheal shave
    • Penile inversion vaginoplasty
  • Masculinizing surgical procedures:
    • Top surgery for transgender men and nonbinary people
    • Body-contouring procedures
    • Hysterectomy/oophorectomy
  • Preoperative and postoperative pelvic floor physical therapy

Before you start treatment, you will meet with at least one member of the TISCC medical team — a doctor or nurse practitioner — and a member of the TISCC behavioral health team, such as a social worker or psychologist. You'll have a complete medical evaluation to make sure that your treatment risks are identified and addressed. Before a surgical procedure you will be seen by the appropriate TISCC surgical team. Evaluation of your mental health ensures that any mood or mental health concerns are reasonably well managed before you start treatment.

Each person is different. Your providers will look at your specific case in order to come up with the best recommendations for you. Your health care team will work with you during your treatment and make sure your expectations are realistic. Your team wants to make sure your goals are being met, any risks are managed and your questions are answered.

Advanced technology

Mayo Clinic specialists are committed to providing the latest, most comprehensive treatment options for gender dysphoria/incongruence. Your Mayo Clinic specialist's advice about the best treatment for you will be based on expert knowledge of and experience with all treatment options for gender dysphoria.

Expertise and rankings

At Mayo Clinic, endocrinologists, psychiatrists, psychologists, nurse practitioners, social workers and surgeons work together to provide exactly the care you need.

Having all of this expertise in a single place, focused on you, means that you're not just getting one opinion — your care is discussed among the team, your test results are available quickly, your appointments are scheduled in coordination and highly specialized experts are all working together to determine what's best for you.

More information about billing and insurance:

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March 24, 2022
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Transgender voice therapy and surgery