Mayo Clinic's approach

Cutting-edge technology

Mayo Clinic surgeons can use a robotic arm in certain cases to help guide reshaping of bone for implant placement. This helps improve the balance in the knee's soft tissues and leads to better alignment and function. Innovative navigation techniques during surgery help procedures go more smoothly and quickly.


Mayo Clinic's knee replacement teams include specialists in orthopedic surgery, anesthesiology and perioperative medicine, and physical medicine and rehabilitation. These experts work together with the goal of easing pain and restoring function.


Mayo Clinic combines innovation with compassion to provide exceptional care. The experts at Mayo know that pain management is a concern for anyone considering surgery. The surgical and anesthesia teams will make you as comfortable as possible during and after the procedure.

The Mayo Clinic experience and patient stories

Our patients tell us that the quality of their interactions, our attention to detail and the efficiency of their visits mean health care like they've never experienced. See the stories of satisfied Mayo Clinic patients.

Expertise and rankings

Mayo Clinic's joint replacement database contains information on every joint replacement surgery performed at Mayo Clinic. The database helps Mayo Clinic doctors determine which surgical technique and prosthesis type will be the most effective for you. The database also has led doctors to many improvements in surgical techniques and prosthesis designs.

Mayo Clinic surgeons perform more than 2,100 knee replacement surgeries annually.

Mayo Clinic in Rochester, Minnesota, Mayo Clinic in Phoenix/Scottsdale, Arizona, and Mayo Clinic in Jacksonville, Florida, are ranked among the Best Hospitals for orthopedics by U.S. News & World Report.

Learn more about Mayo Clinic's orthopedic surgery department's expertise and rankings.

Locations, travel and lodging

Mayo Clinic has major campuses in Phoenix and Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota. The Mayo Clinic Health System has dozens of locations in several states.

For more information on visiting Mayo Clinic, choose your location below:

Costs and insurance

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people.

In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals, or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Learn more about appointments at Mayo Clinic.

Please contact your insurance company to verify medical coverage and to obtain any needed authorization prior to your visit. Often, your insurer's customer service number is printed on the back of your insurance card.

More information about billing and insurance:

Mayo Clinic in Arizona, Florida and Minnesota

Mayo Clinic Health System

Clinical trials

Explore Mayo Clinic studies of tests and procedures to help prevent, detect, treat or manage conditions.

Dec. 21, 2022
  1. Frontera WR, et al., eds. Total knee arthroplasty. In: Essentials of Physical Medicine and Rehabilitation: Musculoskeletal Disorders, Pain, and Rehabilitation. 4th ed. Elsevier; 2019. Accessed Nov. 1, 2022.
  2. Martin GM, et al. Total knee arthroplasty. Accessed Nov. 1, 2022.
  3. Knee replacement. American Academy of Orthopaedic Surgeons. Accessed Nov. 1, 2022.
  4. AskMayoExpert. Knee replacement. Mayo Clinic; 2021.
  5. Martin GM, et al. Complications of total knee arthroplasty. Accessed Nov. 1, 2022.
  6. Health Education & Content Services (Patient Education). Total knee replacement surgery. Mayo Clinic; 2018.
  7. Ami TR. Allscripts EPSi. Mayo Clinic. Oct. 4, 2022.