Estrogen blocker therapy for breast cancer

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Displaying 1-1 out of 1 doctors available

  1. Sandhya Pruthi, M.D.

    Sandhya Pruthi, M.D.

    1. Family Physician
    1. Rochester, MN
    Areas of focus:

    Breast biopsy, Breast self-exam, Breast cancer supportive therapy and survivorship service, Hormone therapy for breast ...cancer, Breast cancer, Fibroadenoma, Atypical hyperplasia of the breast, Breast cysts and lumps, Lobular carcinoma in situ, Breast pain, Fibrocystic breast disease, Phyllodes tumor

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By Mayo Clinic Staff
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About
Aug. 28, 2026
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  1. Breast cancer. National Comprehensive Cancer Network. https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1419. Accessed Aug. 3, 2026.
  2. Hormone therapy for breast cancer. National Cancer Institute. https://www.cancer.gov/types/breast/treatment/hormone-therapy. Accessed Aug. 3, 2026.
  3. Allison KH, et al. Estrogen and progesterone receptor testing in breast cancer: ASCO/CAP guideline update. Journal of Clinical Oncology. 2020; doi:10.1200/JCO.19.02309.
  4. Burstein HJ, et al. Adjuvant endocrine therapy for women with hormone receptor-positive breast cancer: ASCO clinical practice guideline focused update. Journal of Clinical Oncology. 2019; doi:10.1200/JCO.18.01160.
  5. Burstein HJ, et al. Endocrine treatment and targeted therapy for hormone receptor-positive, human epidermal growth factor receptor 2-negative metastatic breast cancer: ASCO guideline update. Journal of Clinical Oncology. 2021; doi:10.1200/JCO.21.01392.
  6. Papakonstantinou A, et al. Adjuvant endocrine treatment strategies for non-metastatic breast cancer: A network meta-analysis. eClinicalMedicine. 2025; doi:10.1016/j.eclinm.2025.103116.
  7. Pala L, et al. Tailoring the optimal duration of extended adjuvant endocrine therapy in patients with early-stage breast cancer: A systematic review and meta-analysis of randomized clinical trials. The Breast. 2023; doi:10.1016/j.breast.2023.02.012.
  8. Klimberg VS, et al., eds. Systemic therapy of hormone-sensitive HER2-negative breast cancer: Adjuvant and neoadjuvant. In: Bland and Copeland's The Breast: Comprehensive Management of Benign and Malignant Diseases. 6th ed. Elsevier; 2024. https://www.clinicalkey.com. Accessed Aug. 3, 2026.
  9. Zuo H, et al. Impact of early discontinuation of adjuvant endocrine therapy on survival in breast cancer: A target trial emulation. European Journal of Cancer. 2025; doi:10.1016/j.ejca.2025.115665.
  10. Eliassen FM, et al. Importance of endocrine treatment adherence and persistence in breast cancer survivorship: A systematic review. BMC Cancer. 2023; doi:10.1186/s12885-023-11122-8.
  11. AskMayoExpert. Invasive breast cancer: Survivorship. Mayo Clinic; 2021.
  12. Gradishar WJ, et al. NCCN Clinical Practice Guidelines in Oncology: Breast Cancer, Version 3.2024. Journal of the National Comprehensive Cancer Network. 2024; doi:10.6004/jnccn.2024.0035.
  13. Gradishar WJ, et al. NCCN Guidelines Insights: Breast Cancer, Version 5.2025. Journal of the National Comprehensive Cancer Network. 2025; doi:10.6004/jnccn.2025.0053.
  14. Ma Y, et al. Symptom experience in endocrine therapy for breast cancer patients: A qualitative systematic review and meta-synthesis. Asia-Pacific Journal of Oncology Nursing. 2024; doi:10.1016/j.apjon.2023.100364.
  15. Orserdu (prescribing information). Stemline Therapeutics Inc.; 2026. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=aa66ae5c-2bd2-4444-8178-b55651e054ef. Accessed Aug. 10, 2026.
  16. Medical review (expert opinion). Mayo Clinic. Aug. 7, 2026.
  17. Campone M, et al. Vepdegestrant, a PROTAC estrogen receptor degrader, in advanced breast cancer. New England Journal of Medicine. 2025; doi:10.1056/NEJMoa2505725.

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Estrogen blocker therapy for breast cancer