Nipple-sparing mastectomy

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Doctors who perform this procedure

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Displaying 11-12 out of 12 doctors available

  1. Mara A. Piltin, D.O.

    Mara A. Piltin, D.O.

    1. Surgical Oncologist
    1. Jacksonville, FL
    Areas of focus:

    Breast biopsy, Breast surgery, Mastectomy, Lumpectomy, Excisional biopsy, Breast duct excision, Prophylactic mastectomy..., Breast cancer surgery, Lymphadenectomy, Melanoma surgery, Sentinel node biopsy, Minimally invasive surgery, Robotic surgery, Flat aesthetic closure, Sentinel lymph node surgery, Nipple-sparing mastectomy, TVEC injection, Lymph node biopsy, Double mastectomy, Breast abscess drainage, Breast cancer, Fibroadenoma, Atypical hyperplasia of the breast, BRCA gene mutation, Melanoma, Breast cysts and lumps, Lobular carcinoma in situ, Squamous cell carcinoma of the skin, Ductal carcinoma in situ, Invasive lobular carcinoma, Paget's disease of the breast, Inflammatory breast cancer, Recurrent breast cancer, Tubular breast cancer, Male breast cancer, Merkel cell carcinoma, Triple-positive breast cancer, Triple-negative breast cancer, Medullary breast cancer, HER2-positive breast cancer, Squamous cell carcinoma of the breast, Invasive ductal carcinoma, Luminal A breast cancer, Phyllodes tumor, Luminal B breast cancer, Papillary breast cancer, Mucinous breast cancer, Paget's disease of the nipple, Stage 4 breast cancer, Atypical lobular hyperplasia, Atypical ductal hyperplasia

  2. Barbara A. Pockaj, M.D.

    Barbara A. Pockaj, M.D.

    1. Surgical Oncologist
    2. General Surgeon
    1. Phoenix, AZ
    Areas of focus:

    Breast surgery, Mastectomy, Breast duct excision, Breast cancer surgery, Sentinel lymph node surgery, Nipple-sparing ma...stectomy, Breast cancer, Fibroadenoma, Atypical hyperplasia of the breast, BRCA gene mutation, Breast cysts and lumps, Ductal carcinoma in situ, Male breast cancer

Research

Mayo Clinic breast cancer surgeons regularly participate in research activities designed to improve care for people with breast cancer.

Areas of research include:

  • Helping people with a higher risk of breast cancer. Mayo Clinic researchers found nipple-sparing mastectomy to be safe for women with BRCA1 and BRCA2 genes undergoing prophylactic mastectomy.
  • Personalizing breast cancer treatments. Researchers are working on the latest treatments that take into account your genes and the particular genes of your cancer cells to offer precision medicine for breast cancer. Examples include discovering new biomarkers for targeted therapy and engineering vaccines to prevent breast cancer recurrence.
  • Relieving pain after mastectomy. Pain control techniques before, during and after mastectomy are reducing the need for strong pain medications during recovery. This includes procedures such as bilateral mastectomy and mastectomy with immediate reconstruction.
  • Understanding how breast cancer develops. Researchers are working to understand the conditions under which breast cancer begins to develop. Research has focused on the unique microorganisms present within the breast. This is sometimes called the breast microbiome. These investigations may yield data that can help prevent breast cancer or devise the most effective treatments.

Publications

See a list of publications about nipple-sparing mastectomy by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles

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By Mayo Clinic Staff

Nipple-sparing mastectomy care at Mayo Clinic

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AboutMayo Clinic's approach
April 07, 2026
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  1. Neligan PC, et al., eds. Preoperative evaluation and planning for breast reconstruction following mastectomy. In: Plastic Surgery. 5th ed. Elsevier; 2024. https://www.clinicalkey.com. Accessed Feb. 11, 2026.
  2. Farhadieh RD, et al., eds. Breast reconstruction. In: Plastic Surgery: Principles and Practice. Elsevier; 2022. https://www.clinicalkey.com. Accessed Feb. 11, 2026.
  3. An N, et al. Comparison of robotic, conventional, and endoscopic nipple-sparing mastectomy with immediate prosthetic breast reconstruction for breast cancer: A systematic review and meta-analysis. Biomolecules and Biomedicine. 2025; doi:10.17305/bb.2025.11687.
  4. Sorenson TJ, et al. Nipple areolar complex (NAC) neurotization after nipple-sparing mastectomy (NSM) in implant-based breast reconstruction: A systematic review of the literature. The Breast Journal. 2025; doi:10.1155/tbj/2362697.
  5. Galimberti V, et al. Nipple-sparing and skin-sparing mastectomy: Review of aims, oncological safety and contraindications. The Breast. 2017; doi:10.1016/j.breast.2017.06.034.
  6. Jakub JW, et al. Oncologic safety of prophylactic nipple-sparing mastectomy in a population with BRCA mutations: A multi-institutional study. JAMA Surgery. 2018; doi:10.1001/jamasurg.2017.3422.
  7. Peled AW, et al. Novel approaches to breast reconstruction. Surgical Clinics of North America. 2023; doi:10.1016/j.suc.2022.08.008.
  8. Webster AJ, et al. Oncologic safety of nipple-sparing mastectomy for breast cancer in BRCA gene mutation carriers: Outcomes at 70 months median follow-up. Annals of Surgical Oncology. 2023; doi:10.1245/s10434-022-13006-w.
  9. Breast cancer. National Comprehensive Cancer Network. https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1419. Accessed Feb. 13, 2026.
  10. Mastectomy. https://www.uptodate.com/contents/search. Accessed Feb. 13, 2026.
  11. AskMayoExpert. DCIS. Mayo Clinic; 2022.
  12. Health Education & Content Services. Surgical treatments for breast cancer. Mayo Clinic; 2026.
  13. De La Cruz L, et al. Overall survival, disease-free survival, local recurrence, and nipple–areolar recurrence in the setting of nipple-sparing mastectomy: A meta-analysis and systematic review. Annals of Surgical Oncology. 2015; doi:10.1245/s10434-015-4739-1.
  14. Agha RA, et al. Systematic review of therapeutic nipple-sparing versus skin-sparing mastectomy. BJS Open. 2019; doi:10.1002/bjs5.50119.
  15. S Mengqing, et al. Long-term outcomes of skin-sparing mastectomy and nipple-sparing mastectomy versus traditional mastectomy in breast cancer: A case-control study based on preoperative ultrasound and clinical indicators. World Journal of Surgical Oncology. 2025; doi:10.1186/s12957-025-03695-4.

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