Mayo Clinic's approach

Mayo Clinic's highly trained breast cancer surgeons work in coordinated surgical teams with plastic reconstruction surgeons for surgeries such as nipple-sparing mastectomies. They use the latest advances to care for people with breast cancer and those at higher risk of developing the disease in the future.

Robotic nipple-sparing mastectomy at Mayo Clinic

Mayo Clinic Comprehensive Cancer Center offers robotic nipple-sparing mastectomy at its Minnesota and Florida campuses. This surgical option is available for some people being treated for breast cancer or those having preventive procedures.

After the Food and Drug Administration's clearance of the robotic platform for nipple-sparing mastectomy, Mayo Clinic surgeons — who helped test it in clinical trials — now perform this less invasive surgery. With this procedure, Mayo surgeons aim to improve appearance, keep the nipple intact and create better chances for restoring sensation.

Your Mayo Clinic care team

People with breast cancer who choose Mayo Clinic for breast cancer surgery find highly experienced surgeons who provide expert care. Breast cancer surgeons work closely with other specialists to create a personalized treatment approach that provides you with comprehensive care.

Your care team might include:

Your appointments are coordinated so that you can carefully consider your options and meet with a variety of specialists, often in a matter of days. If you choose surgery as your initial treatment, your operation is scheduled promptly, when possible, to avoid long wait times.

Expertise and rankings

Mayo Clinic breast cancer surgeons are widely respected for their experience and knowledge in advanced surgical techniques that improve cancer control and reduce the complications of breast cancer surgery.

Nationally recognized expertise

Outside organizations recognize Mayo Clinic breast cancer specialists through accreditations, grants and rankings:

  • Mayo Clinic is accredited by the American College of Surgeons' Commission on Cancer.
  • Mayo Clinic is one of a select group of medical centers in the United States to be recognized as a Specialized Program of Research Excellence (SPORE) for breast cancer research, funded by the National Cancer Institute. To earn a highly competitive SPORE grant, institutions must demonstrate a high degree of collaboration between first-rate scientists and clinicians and show excellence in translational research projects. Learn more about the Mayo Clinic Breast Cancer SPORE.
  • Mayo Clinic doctors and researchers participate in research cooperatives, such as the Alliance for Clinical Trials in Oncology, which gives people with cancer access to the latest clinical trials.

Mayo Clinic Comprehensive Cancer Center meets the strict standards for a U.S. National Cancer Institute comprehensive cancer center. These standards recognize scientific excellence and a multispecialty approach focused on cancer prevention, diagnosis and treatment.

Mayo Clinic in Rochester, Minnesota, Mayo Clinic in Jacksonville, Florida, and Mayo Clinic in Phoenix/Scottsdale, Arizona, are ranked among the Best Hospitals for cancer by U.S. News & World Report.

Locations, travel and lodging

Mayo Clinic has major campuses in Phoenix and Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota. The Mayo Clinic Health System has dozens of locations in several states.

For more information on visiting Mayo Clinic, choose your location below:

Costs and insurance

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people.

In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Learn more about appointments at Mayo Clinic.

Please contact your insurance company to verify medical coverage and to obtain any needed authorization prior to your visit. Often, your insurer's customer service number is printed on the back of your insurance card.

More information about billing and insurance:

Mayo Clinic in Arizona, Florida and Minnesota

Mayo Clinic Health System

Clinical trials

Explore Mayo Clinic studies of tests and procedures to help prevent, detect, treat or manage conditions.

April 07, 2026
  1. Neligan PC, et al., eds. Preoperative evaluation and planning for breast reconstruction following mastectomy. In: Plastic Surgery. 5th ed. Elsevier; 2024. https://www.clinicalkey.com. Accessed Feb. 11, 2026.
  2. Farhadieh RD, et al., eds. Breast reconstruction. In: Plastic Surgery: Principles and Practice. Elsevier; 2022. https://www.clinicalkey.com. Accessed Feb. 11, 2026.
  3. An N, et al. Comparison of robotic, conventional, and endoscopic nipple-sparing mastectomy with immediate prosthetic breast reconstruction for breast cancer: A systematic review and meta-analysis. Biomolecules and Biomedicine. 2025; doi:10.17305/bb.2025.11687.
  4. Sorenson TJ, et al. Nipple areolar complex (NAC) neurotization after nipple-sparing mastectomy (NSM) in implant-based breast reconstruction: A systematic review of the literature. The Breast Journal. 2025; doi:10.1155/tbj/2362697.
  5. Galimberti V, et al. Nipple-sparing and skin-sparing mastectomy: Review of aims, oncological safety and contraindications. The Breast. 2017; doi:10.1016/j.breast.2017.06.034.
  6. Jakub JW, et al. Oncologic safety of prophylactic nipple-sparing mastectomy in a population with BRCA mutations: A multi-institutional study. JAMA Surgery. 2018; doi:10.1001/jamasurg.2017.3422.
  7. Peled AW, et al. Novel approaches to breast reconstruction. Surgical Clinics of North America. 2023; doi:10.1016/j.suc.2022.08.008.
  8. Webster AJ, et al. Oncologic safety of nipple-sparing mastectomy for breast cancer in BRCA gene mutation carriers: Outcomes at 70 months median follow-up. Annals of Surgical Oncology. 2023; doi:10.1245/s10434-022-13006-w.
  9. Breast cancer. National Comprehensive Cancer Network. https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1419. Accessed Feb. 13, 2026.
  10. Mastectomy. https://www.uptodate.com/contents/search. Accessed Feb. 13, 2026.
  11. AskMayoExpert. DCIS. Mayo Clinic; 2022.
  12. Health Education & Content Services. Surgical treatments for breast cancer. Mayo Clinic; 2026.
  13. De La Cruz L, et al. Overall survival, disease-free survival, local recurrence, and nipple–areolar recurrence in the setting of nipple-sparing mastectomy: A meta-analysis and systematic review. Annals of Surgical Oncology. 2015; doi:10.1245/s10434-015-4739-1.
  14. Agha RA, et al. Systematic review of therapeutic nipple-sparing versus skin-sparing mastectomy. BJS Open. 2019; doi:10.1002/bjs5.50119.
  15. S Mengqing, et al. Long-term outcomes of skin-sparing mastectomy and nipple-sparing mastectomy versus traditional mastectomy in breast cancer: A case-control study based on preoperative ultrasound and clinical indicators. World Journal of Surgical Oncology. 2025; doi:10.1186/s12957-025-03695-4.