Side effects of cryotherapy for prostate cancer can include:

  • Erectile dysfunction
  • Pain and swelling of the scrotum and penis
  • Frequent, difficult or painful urination
  • Blood in your urine
  • Loss of bladder control
  • Bleeding or infection in the area treated

Rarely, side effects can include:

  • Injury to the rectum
  • Blockage of the tube (urethra) that carries urine out of the body
  • Infection or inflammation of the pubic bone
Aug. 15, 2017
  1. Wein AJ, et al., eds. Focal therapy for prostate cancer. In: Campbell-Walsh Urology. 11th ed. Philadelphia, Pa.: Elsevier; 2016. http://www.clinicalkey.com. Accessed Feb. 3, 2016.
  2. Pisters LL, et al. Cryotherapy and other ablative techniques for the initial treatment of prostate cancer. http://www.uptodate.com/home. Accessed Feb. 3, 2016.
  3. Marien A, et al. Target ablation — Image-guided therapy in prostate cancer. Urologic Oncology: Seminars and Original Investigations. 2014;32:912.
  4. Moul JW. Rising serum PSA after radiation therapy for localized prostate cancer: Salvage local therapy. http://www.uptodate.com/home. Accessed Feb. 3, 2016.
  5. Friedlander DF, et al. Population-based comparative effectiveness of salvage radical prostatectomy vs cryotherapy. Urology. 2014;83:653.
  6. Castle EP (expert opinion). Mayo Clinic, Scottsdale, Ariz. Feb. 12, 2016.
  7. Cryosurgery for prostate cancer. American Cancer Society. http://www.cancer.org/cancer/prostatecancer/detailedguide/prostate-cancer-treating-cryosurgery. Accessed Feb. 3, 2016.

Cryotherapy for prostate cancer