Search Results 11-20 of 15071 for Proto-oncogene

  1. Discovery's Edge: Battling brain cancers through genomics - Mayo Clinic News Network

    These cancer-causing genes can take on three different forms. Oncogenes act like the accelerator of the car: mutations in these genes put the pedal to the metal ...

  2. Publications

    RET proto-oncogene genotyping using unlabeled probes ... Nine novel germline gene variants in the RET proto-oncogene identified in twelve unrelated cases.

  3. Focus Areas - Department of Cancer Biology - Mayo Clinic Research

    Cancer disparities · Cancer stem cells · Cancer systems biology · Oncogenic gene dysregulation and carcinogenesis · Precision cancer medicine and translational ...

  4. Tumor Microenvironment - Department of Cancer Biology - Mayo Clinic Research

    Dr. Ji's team developed experimental systems that specifically target oncogenes and tumor suppressors in the cells of interest. These systems can be used to ...

  5. A Study Evaluating Fecal DNA Markers to Detect Colorectal Neoplasia in Patients with Inflammatory Bowel Disease - Mayo Clinic

    About this study. Cells with increased oncogene activity adopt a secretory phenotype. For example, increased levels of c-Src not only inhibit ...

  6. Overview - Molecular Mechanisms of Tumorigenesis: Verline Justilien - Mayo Clinic Research

    In her Molecular Mechanisms of Tumorigenesis Lab at Mayo Clinic, Verline Justilien, Ph.D., hopes to identify oncogenic drivers of lung cancer and pancreas ...

  7. Uncovering Signaling Pathways That Regulate Invasion and Metastasis of Cancer Cells - Tumor Development, Immunology and Progression Laboratory - Mayo Clinic Research

    While PKD1 mediates cell proliferation and also acts as a suppressor of breast tumor cell invasion, PKD3, when expressed, mediates all oncogenic functions.

  8. Genome Function, Stability and Nuclear Organization in Cancer: Veronica Rodriguez-Bravo - Mayo Clinic Research

    Rodriguez-Bravo, studies cell and molecular biology mechanisms of genome organization and stability regulation in cancer. The lab has a special interest in ...

  9. Enzyme that regulates DNA repair may offer new precision treatments for breast and ovarian cancer - Mayo Clinic News Network

    “The BRCA2 pathway is important for DNA repair, and mutation of the BRCA2 gene is linked to increased cancer risk, especially breast cancer and ovarian cancer.”.

  10. A Study to Evaluate Immunotherapy for Non-Small Cell Lung Cancer - Mayo Clinic

    (ALK), B-Raf proto-oncogene (BRAF) or ROS proto-oncogene 1 (ROS1) mutations who have not received appropriate therapies targeting these mutations and ...