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Search Results 21-30 of 79 for Proto-oncogene
Specifically, we are interested in the role of epidermal growth factor receptor (EGFR), a frequently mutated oncogene in gliomas, and its effect on the expression of effector molecules (integrins and proteinases) that drive tumor inv...
Moreover, clusters of active enhancers called super-enhancers (SEs) that allow robust transcription of lineage-specific genes also can mediate dysregulated expression of oncogenes, such as MYC.
Study IDs Site IRB Rochester, Minnesota: 14-000209 NCT ID: NCT02003222 Sponsor Protocol Number: E1910 About this study This randomized phase III trial studies combination chemotherapy with blinatumomab to see how well it works compared to induction c...
In previous work, Mayo Clinic investigators in the Ovarian Cancer SPORE provided the first evidence that protein kinase C iota (PKCɩ), which is located in the middle of this amplicon, is an oncogene.
He has published over 500 articles, editorials and book chapters in peer-reviewed journals such as American Journal of Gastroenterology, Hepatology, Gastroenterology, Nature Medicine, Journal of Clinical Investigation, Journal of Biological Chemistry...
Study IDs Site IRB Rochester, Minnesota: 14-002511 Jacksonville, Florida: 14-002511 Scottsdale/Phoenix, Arizona: 14-002511 NCT ID: NCT02083484 Sponsor Protocol Number: MK-3475-030 About this study This is an expanded access program (EAP) for particip...
Oncogene dysregulation in lymphoma.
A current focus is on the MYC oncogene that appears in some patients to cause the progression of MGUS to myeloma.
Within the area of thyroid cancer, our basic research group is interested in oncogenes, tumor suppressor genes, and the identification of other genes involved in the initiation or spread of malignancy.
These results demonstrated that that NFATc1 was a potent oncogene in pancreatic ductal adenocarcinoma.
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