Search Results 21-30 of 15077 for Proto-oncogene

  1. Overview - Proteases in Cancer Laboratory - Mayo Clinic Research

    The Proteases in Cancer Lab led by Evette S. Radisky, Ph.D., at Mayo Clinic studies proteases and designs better agents for blocking tumor invasion and the ...

  2. Drug Combo Shuts Down Stem Cells, Tumor Growth in Lung Cancer - Mayo Clinic News Network

    Found PKCiota activates a second oncogene, known as SOX2, to stimulate cancer stem cell growth in lung squamous cell carcinoma. Dr. Fields says the current ...

  3. Renal Cancer: A Paradigm for Understanding How Mutations in Epigenetic Regulator Genes Drive Cancer Initiation and Progression - Research - Mayo Clinic Research

    The Epigenetic Etiology of Human Disease Laboratory at Mayo Clinic is studying epigenetic mutations at the epigenome and transcriptome levels.

  4. Tumor Molecular Analysis - Mayo Clinic

    Molecular characterization may include short tandem DNA repeat; STR) and oncogenic/tumor suppressor gene mutation analyses to assure that the derived models ...

  5. Beating Advanced Cancers: New Epigenomic Block for Advanced Cancer Progression - Mayo Clinic News Network

    The precision medicine study appears online in Oncogene and focuses on kidney cancer and its metastases. Recent studies of the same epigenomic fingerprint ...

  6. Cancer-Causing Gene Alone Doesn't Trigger Pancreatic Cancer, Mayo-led Study Finds

    The study, published in the Sept. 10 issue of Cancer Cell, overturns the current belief that a mutation in the KRAS oncogene is enough to initiate pancreatic ...

  7. Mayo Clinic researchers find new code that makes reprogramming of cancer cells possible

    ... oncogenic,” Dr. Anastasiadis says. “We believe that loss of the apical PLEKHA7-microprocessor complex is an early and somewhat universal event in cancer ...

  8. Genome Function, Stability and Nuclear Organization in Cancer: Veronica Rodriguez-Bravo - Mayo Clinic Research

    The team is exposing, at the molecular level, the routes that aggressive tumor cells take to adapt and survive high levels of chromosomal instability (CIN). Her ...

  9. Transgenic and Knockout Core - Mayo Clinic Comprehensive Cancer Center Research

    Transgenic and gene-targeted mouse models enable Mayo Clinic cancer researchers to study in vivo how the overexpression of specific genes and their mutants is ...

  10. Active Grants — Cancer and Cell Aging Platform - Center for Biomedical Discovery - Mayo Clinic Research

    The investigative team developed a novel zebrafish model of neuroblastoma metastasis by overexpressing the human MYCN oncogene and knocking out the GAS7 gene.