Search Results 41-50 of 16433 for Inhibition

  1. Overview - Proteases in Cancer Laboratory - Mayo Clinic Research

    Blocking tumor invasion and metastasis. Dr. Radisky's research targets the natural interactions between enzymes and their endogenous inhibitors.

  2. Study of IDO Inhibitor in Combination With Checkpoint Inhibitors for Adult Patients With Metastatic Melanoma - Mayo Clinic

    About this study. To evaluate the preliminary efficacy of the established dose of indoximod in combination with immune checkpoint inhibition as measured by ...

  3. Phase 1/2 Study of TP-0903 (an Inhibitor of AXL Kinase) in Patients With Previously Treated CLL - Mayo Clinic

    TP-0903 has shown potent inhibition of AXL kinase and other TAM family members in a biochemical kinase assay. TP-0903 demonstrates corresponding activity in ...

  4. Study of Bcl-2 Inhibitor BGB-11417 in Participants With Mature B-Cell Malignancies - Mayo Clinic

    About this study. The purpose of this study is to determine the safety and tolerability of and to define the maximum tolerated dose (MTD) and Recommended ...

  5. Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in Adults - Mayo Clinic

    About this study. This phase III trial compares the effect of usual treatment of chemotherapy and steroids and a tyrosine kinase inhibitor (TKI) to the same ...

  6. Carbonic Anhydrase Inhibitor (Oral Route, Parenteral Route) Side Effects - Mayo Clinic

    Dryness of mouth · increased thirst · irregular heartbeats · mood or mental changes · muscle cramps or pain · nausea or vomiting · unusual tiredness or weakness · weak ...

  7. Alpha-1 Proteinase Inhibitor Human (Intravenous Route) Side Effects - Mayo Clinic

    Bladder pain · bloody or cloudy urine · body aches or pain · chills · cough · difficult, burning, or painful urination · difficulty with breathing · ear congestion ...

  8. Development of PARP Inhibitors and DDR Modifiers To Treat Ovarian Cancer - Anticancer Drug Action Laboratory - Mayo Clinic Research

    Dr. Kaufmann and his team in the Anticancer Drug Action Lab at Mayo Clinic are studying the susceptibility of HR-deficient cancer cells to PARP inhibitors ...

  9. Carbonic Anhydrase Inhibitor (Oral Route, Parenteral Route) Precautions - Mayo Clinic

    This medicine may cause some people to feel drowsy, dizzy, lightheaded, or more tired than they are normally. Make sure you know how you react to this medicine ...

  10. MAOIs and diet: Is it necessary to restrict tyramine? - Mayo Clinic

    Medications called monoamine oxidase inhibitors (MAOIs) block monoamine oxidase, which is an enzyme that breaks down excess tyramine in the body. Blocking ...