Search Results 1-10 of 27528 for Alpha-1+antitrypsin+deficiency

  1. Mayo Clinic Q and A: Rare, inherited risk factor can result in emphysema and liver damage

    In those who have alpha-1 antitrypsin deficiency, an abnormal protein is made and it isn't fully released by the liver into the bloodstream. Thus, the lungs ...

  2. Alpha-1 Antitrypsin Mutation in COVID Positive Patients Who Are Hospitalized - Mayo Clinic

    About this study. Patients with alpha-1 antitrypsin deficiency are prone to having an imbalance of lung Elastin degradation which render the patient's ...

  3. COPD - Symptoms and causes - Mayo Clinic

    Alpha-1-antitrypsin deficiency can cause liver disease, lung disease or both. For adults with COPD related to AAt deficiency, treatment options include those ...

  4. Michael J. Krowka, M.D. - Mayo Clinic Faculty Profiles

    Alpha-1 antitrypsin deficiency. This inherited disorder can cause deficiency of a circulating protein that protects the lung. Deficiency of this blood ...

  5. Alpha-1 Proteinase Inhibitor Human (Intravenous Route) Description and Brand Names - Mayo Clinic

    The emphysema is caused by the lack of a protein called alpha 1-antitrypsin (AAT) in the body. This medicine replaces the protein when the body does not ...

  6. centers-of-excellence

    Alpha-1-antitrypsin deficiency: A liver-lung connection March 28, 2015 Alpha-1-antitrypsin (AAt) is a serine protease inhibitor produced primarily in the liver.

  7. Halfway Around the World and in Need of a New Liver

    Alpha-1 antitrypsin is a protein made in the liver that helps protect the lungs and other organs. "AAt deficiency is not very common" says Andrew Keaveny, M.D., ...

  8. Michael J. Krowka, M.D. - Doctors and Medical Staff - Mayo Clinic

    Alpha-1 antitrypsin deficiency. This inherited disorder can cause deficiency of a circulating protein made in the liver that protects the lung. Deficiency ...

  9. A Study to Determine the Safety, Tolerability and Effect on Liver Histologic Parameters of ARO-AAT - Mayo Clinic

    ... alpha-1 antitrypsin deficiency (AATD). Participants will receive multiple subcutaneous doses of ARO-AAT. Participation eligibility. Participant eligibility ...

  10. Emphysema - Symptoms and causes - Mayo Clinic

    Rarely, emphysema is caused by an inherited deficiency of a protein that protects the elastic structures in the lungs. It's called alpha-1-antitrypsin ...