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  1. Efficacy and Safety Study of Benralizumab to Reduce OCS Use in Patients With Uncontrolled Asthma on High Dose Inhaled Corticosteroid Plus LABA and Chronic OCS Therapy - Mayo Clinic

    The purpose of this trial is to confirm if benralizumab can reduce OCS dependence (after dose optimisation) in patients who are uncontrolled on high-dose ICS- ...

  2. A Study to Investigate Mepolizumab in the Treatment of Eosinophilic Granulomatosis With Polyangiitis - Mayo Clinic

    The key outcomes in the study focus on evaluation of clinical remission, defined as Birmingham Vasculitis Activity Score (BVAS)=0 with a corticosteroid dose of ...

  3. Prospective Study of Round Window Versus Cochleostomy Approach to CI Surgery - Mayo Clinic

    In 1985, the United States Food and Drug Administration (FDA) approved multichannel cochlear implants (CIs) for adults with profound hearing loss; ...

  4. Combination Vaccine Immunotherapy (DRibbles) for Patients with Definitively-treated Stage III Non-small Cell Lung Cancer - Mayo Clinic

    This study will test an investigational vaccine, called DRibbles, for the treatment of non-small cell lung cancer (NSCLC). We hypothesize that vaccination with ...

  5. A Study to Gather Genetic information for Further Study from Patients with Idiopathic Scoliosis and Their Families - Mayo Clinic

    The purpose of this study is to gather samples for identifying genetic factors that make children susceptible to ideopathic scoliosis and influence disease ...

  6. A Study to Evaluate the Effectiveness and Safety of Vutrisiran in Patients with Transthyretin Amyloidosis with Cardiomyopathy (ATTR Amyloidosis with Cardiomyopathy - Mayo Clinic

    The purpose of this study is to evaluate vutrisiran in patients with transthyretin amyloidosis with cardiomyopathy. Participation eligibility. Participant ...

  7. Mobile Educations Effect on Pain Outcomes - Mayo Clinic

    The purpose of this study is to explore the clinical impact of pain management education using a mobile web-based education delivery system compared to standard ...

  8. A Study to Survey Epidural User Experience for Individuals with Spinal Cord Injury Paralysis - Mayo Clinic

    About this study. This is a survey study to identify user-reported motor, sensory, and autonomic functions that are enabled by epidural stimulation, ...

  9. Will Making the HPV Vaccine Available at Mayo Clinic Express Care with Use of Electronic Point of Care Reminder Improve Overall Vaccination Rates Among an Empaneled Adolescent Population?

    The purpose of this study is to determine if a medical record prompt at the time of a medical consult will help to address lapses in routine immunizations, ...

  10. Crossover Feasibility Study of Portable AP Device with Zone-MPC and HMS and Adapted I:C and Basal Insulin - Mayo Clinic

    This proposed study is designed to compare closed-loop control with or without optimization of initialization parameters related to basal insulin infusion rates ...