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1. Is physical exercise associated with significant changes in the frequency or burden of spikes on EEG in children with epilepsy? - Mayo Clinic

   About this study. This study hypothesises that physical exercise in children with epilepsy will be associated with a significant reduction in interictal ...

2. A Study of Niraparib Combination Therapies for the Treatment of Metastatic Castration-Resistant Prostate Cancer - Mayo Clinic

   Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

3. Safety Study of Mocetinostat in Combination With Azacitidine in Subjects With MDS - Mayo Clinic

   Mocetinostat is an orally administered histone deacetylase (HDAC) inhibitor. Azacitidine is a hypomethylating agent (HMA) used to treat MDS. In this study, ...

4. A Study of a Psychotherapeutic Approach Applied to Those Who are Critically Ill to Provide Patients with Psychological Support - Mayo Clinic

   About this study. The objective of this project is to refine and test a behavioral intervention to be administered in parallel with medical treatment in the ...

5. A Study to Collect Patient Data Collected Through Standard of Care Clinical Visits on the Subject of Hydronephrosis (Common Pediatric Urological Disorder that is Detected Prenatally, or Postnatal Infancy) - Mayo Clinic

   About this study. The purpose of this research study is to contribute to an existing registry that was developed by Virginia Commonwealth University (VCU).

6. A Study of the Effectiveness and Safety of Lubiprostone in Pediatric Patients with Functional Constipation - Mayo Clinic

   Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

7. Efficacy and Safety Study of Benralizumab to Reduce OCS Use in Patients With Uncontrolled Asthma on High Dose Inhaled Corticosteroid Plus LABA and Chronic OCS Therapy - Mayo Clinic

   The purpose of this trial is to confirm if benralizumab can reduce OCS dependence (after dose optimisation) in patients who are uncontrolled on high-dose ICS- ...

8. A Study to Investigate Mepolizumab in the Treatment of Eosinophilic Granulomatosis With Polyangiitis - Mayo Clinic

   The key outcomes in the study focus on evaluation of clinical remission, defined as Birmingham Vasculitis Activity Score (BVAS)=0 with a corticosteroid dose of ...

9. Prospective Study of Round Window Versus Cochleostomy Approach to CI Surgery - Mayo Clinic

   In 1985, the United States Food and Drug Administration (FDA) approved multichannel cochlear implants (CIs) for adults with profound hearing loss; ...

10. Combination Vaccine Immunotherapy (DRibbles) for Patients with Definitively-treated Stage III Non-small Cell Lung Cancer - Mayo Clinic

    This study will test an investigational vaccine, called DRibbles, for the treatment of non-small cell lung cancer (NSCLC). We hypothesize that vaccination with ...