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Jeffrey E. Johnson, M.D.

  1. Surgical Oncologist

Jeffrey E. Johnson, M.D., is a surgical oncologist specializing in the management of melanoma and breast cancer. He has expertise in the multimodality treatment of cancer and collaborates with colleagues across Mayo Clinic to coordinate treatment plans integrating surgery, intralesional therapy, radiation, and systemic therapies (chemotherapy, endocrine therapy, immunotherapy). He is dedicated to optimizing oncologic outcomes within a patient-centered framework. Special interests include:

  • Lymph node surgery including sentinel lymph node biopsy
  • Intralesional therapy for melanoma
  • Metastasectomy for melanoma
  • Neoadjuvant therapy for melanoma and breast cancer
  • Nipple-sparing mastectomy and oncoplastic breast surgery
  • Counseling and surgical management of women at high risk for breast cancer

In addition to his clinical activities, Dr. Johnson has research interests in novel therapies for locoregionally advanced melanoma, integration of machine learning in clinical practice, and patient centered outcomes and decision making in cancer care.

  1. Atypical ductal hyperplasia
  2. Atypical hyperplasia of the breast
  3. Atypical lobular hyperplasia
  4. BRCA gene mutation
  5. Breast cancer
  6. Breast cysts and lumps
  7. Ductal carcinoma in situ
  8. Fibroadenoma
  9. HER2 positive invasive breast cancer
  10. Inflammatory breast cancer
  11. Invasive ductal carcinoma
  12. Invasive lobular carcinoma
  13. Lobular carcinoma in situ
  14. Luminal A breast cancer
  15. Luminal B breast cancer
  16. Male breast cancer
  17. Medullary breast cancer
  18. Melanoma
  19. Merkel cell carcinoma
  20. Metastatic breast cancer
  21. Mucinous breast cancer
  22. Paget's disease of the breast
  23. Paget's disease of the nipple
  24. Papillary breast cancer
  25. Phyllodes tumor
  26. Recurrent breast cancer
  27. Skin cancer
  28. Squamous cell carcinoma of the breast
  29. Squamous cell carcinoma of the skin
  30. Triple-negative breast cancer
  31. Triple-positive breast cancer
  32. Tubular breast cancer
  1. Breast abscess drainage
  2. Breast biopsy
  3. Breast cancer surgery
  4. Breast duct excision
  5. Breast surgery
  6. Double mastectomy
  7. Excisional biopsy
  8. Lumpectomy
  9. Lymph node sampling
  10. Lymphadenectomy
  11. Mastectomy
  12. Melanoma surgery
  13. Minimally invasive surgery
  14. Modified radical mastectomy
  15. Nipple-sparing mastectomy
  16. Oncoplastic breast-conserving surgery
  17. Prophylactic mastectomy
  18. Radioactive seed localization
  19. Sentinel lymph node surgery
  20. Sentinel node biopsy
  21. Skin-sparing mastectomy
  22. TVEC injection
  23. Wire localization for breast surgery
  • Breast cancer surgery
  • Melanoma surgery
  • Sentinel lymph node surgery
  • Intralesional therapies for melanoma
  • Translational research
  • Novel therapies and technologies
  • Neoadjuvant systemic therapy
  • Prophylactic mastectomy
  • Nipple sparing mastectomy
  1. 2021
    Fellowship - Complex General Surgical OncologyUniversity of North Carolina at Chapel Hill
  2. 2019
    Residency - General SurgeryDepartment of Surgery, Cedars-Sinai Medical Center
  3. 2017
    Research Fellowship - Surgical Oncology ResearchDepartment of Surgery, Cedars-Sinai Medical Center
  4. 2012
    MDWeill Cornell Medical College
  5. 2007
    BA - Classical Studies with HonorsWillamette University


  1. 2022
    Complex General Surgical OncologyAmerican Board of Surgery
  2. 2020
    General SurgeryAmerican Board of Surgery

Awards and honors

  1. 2018
    Residents' Teaching AwardCedars-Sinai Medical Center
  2. 2015
    Basic/Translational Research Poster Award, FinalistAnnual Symposium, Society of Surgical Oncology
  3. 2012
    Resident Prize for Best Research PresentationNew York Chapter, American College of Surgeons
  4. 2007
    Phi Beta KappaWillamette University
  5. 2007
    Magna cum laudeWillamette University

Professional memberships

  1. 2021 - present
    MemberAmerican Society of Breast Surgeons
  2. 2018 - present
    MemberSociety of Surgical Oncology
  3. 2017 - present
    MemberAmerican College of Surgeons