Your doctor should check your progress at regular visits while you are taking this medicine.
Before you have any medical tests, tell the person in charge that you are taking this medicine. The results of some tests may be affected by probenecid or by colchicine.
For diabetic patients:
The probenecid in this combination medicine may cause false test results with copper sulfate urine sugar tests (e.g., Clinitest®), but not with glucose enzymatic urine sugar tests (e.g., Clinistix®). If you have any questions about this, check with your health care professional.
Taking aspirin or other salicylates may lessen the effects of the probenecid in this combination medicine. This will depend on the dose of aspirin or other salicylate that you take, and on how often you take it. Also, drinking large amounts of alcoholic beverages may increase the chance of stomach problems and may increase the amount of uric acid in your blood. Therefore, do not take aspirin or other salicylates or drink alcoholic beverages while you are taking this medicine, unless you have first checked with your doctor.
For patients taking 4 tablets or more of this medicine a day:
Stop taking this medicine immediately and check with your doctor as soon as possible if severe diarrhea, nausea or vomiting, or stomach pain occurs while you are taking this medicine.