Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

  1. Bloating or swelling of the face, arms, hands, lower legs, or feet
  2. blue lips, fingernails, or skin
  3. blurred vision
  4. changes in skin color
  5. chest pain
  6. confusion
  7. cough
  8. cracked lips
  9. decreased urine
  10. diarrhea
  11. difficult or troubled breathing
  12. difficulty with swallowing
  13. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  14. dry mouth
  15. fever
  16. headache
  17. increased thirst
  18. irregular heartbeat
  19. irregular, fast, slow, or shallow breathing
  20. loss of appetite
  21. mood changes
  22. muscle pain or cramps
  23. nausea
  24. nervousness
  25. numbness or tingling in your hands, feet, or lips
  26. pain or redness at the injection site
  27. pain, tenderness, or swelling of the foot or leg
  28. pale skin
  29. pounding in the ears
  30. rapid weight gain
  31. seizures
  32. slow or fast heartbeat
  33. sneezing
  34. sore throat
  35. sores, ulcers, or white spots on the lips, tongue, or inside the mouth
  36. sweating
  37. tightness in the chest
  38. troubled breathing with exertion
  39. unusual bleeding or bruising
  40. unusual tiredness or weakness
  41. unusual weight gain or loss
  42. vomiting

Less common

  1. Bloody urine
  2. decreased frequency or amount of urine
  3. increased blood pressure
  4. lower back or side pain
  5. weight gain
  6. yellow eyes or skin

Incidence not known

  1. Black, tarry stools
  2. bladder pain
  3. bleeding gums
  4. blood in the urine or stools
  5. bloody nose
  6. chest pain or discomfort
  7. clay-colored stools
  8. cloudy urine
  9. constipation
  10. dark urine
  11. decreased appetite
  12. depression
  13. drowsiness
  14. fever with or without chills
  15. flushed, dry skin
  16. frequent urge to urinate
  17. fruit-like breath odor
  18. general feeling of tiredness or weakness
  19. incoherent speech
  20. increased hunger
  21. increased urination
  22. indigestion
  23. itching
  24. light-colored stools
  25. metallic taste
  26. muscle spasms (tetany) or twitching seizures
  27. muscle weakness
  28. no blood pressure or pulse
  29. noisy, rattling breathing
  30. pain or discomfort in the arms, jaw, back, or neck
  31. pains in the stomach, side, or abdomen, possibly radiating to the back
  32. pinpoint red spots on the skin
  33. rapid weight gain
  34. rash
  35. right upper abdominal or stomach pain and fullness
  36. shakiness in the legs, arms, hands, or feet
  37. stomach pain, continuous
  38. stomach pain or tenderness
  39. stopping of heart
  40. trembling or shaking of the hands or feet
  41. troubled breathing at rest
  42. ulcers, sores, or white spots in the mouth
  43. unconsciousness
  44. unexplained weight loss
  45. unpleasant breath odor
  46. vomiting of blood
  47. weakness
  48. weight loss

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Flushing, redness of the skin
  2. unusually warm skin

Incidence not known

  1. Back pain
  2. belching
  3. blistering, peeling, or loosening of the skin
  4. bloated or feeling of fullness
  5. bumps on the skin
  6. difficulty in moving
  7. dry, red, hot, or irritated skin
  8. fear
  9. flaking and falling off of the skin
  10. heartburn
  11. hives or welts
  12. indigestion
  13. joint or muscle pain
  14. lack or loss of strength
  15. muscle pain or stiffness
  16. pressure in the stomach
  17. red skin lesions, often with a purple center
  18. red, irritated eyes
  19. redness of the skin
  20. sleepiness or unusual drowsiness
  21. small red or purple spots on the skin
  22. stomach discomfort, upset, or pain
  23. swelling of the abdominal or stomach area
  24. trouble sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.