Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Black, tarry stools
  2. bleeding gums
  3. blood in the urine or stools
  4. chest tightness
  5. chills
  6. cough
  7. difficult or labored breathing
  8. fever
  9. lower back or side pain
  10. painful or difficult urination
  11. pale skin
  12. pinpoint red spots on the skin
  13. sore throat
  14. swelling of the hands, ankles, feet, or lower legs
  15. trouble breathing
  16. ulcers, sores, or white spots in the mouth
  17. unusual bleeding or bruising
  18. unusual tiredness or weakness

Less common

  1. Agitation
  2. chest pain or discomfort
  3. clay-colored stools
  4. cough with mucus
  5. confusion
  6. dark urine
  7. decreased appetite
  8. decreased urination
  9. depression
  10. diarrhea
  11. dizziness
  12. dry mouth
  13. fainting
  14. fast or irregular heartbeat
  15. general feeling of discomfort or illness
  16. headache
  17. hives, itching, or skin rash
  18. hoarseness
  19. hostility
  20. increased sweating
  21. increased thirst
  22. irritation
  23. joint pain, stiffness or swelling
  24. lightheadedness
  25. loss of appetite
  26. muscle aches, pains, or twitching
  27. nausea
  28. numbness or tingling in the hands, feet, or lips
  29. rapid breathing
  30. rapid weight gain
  31. redness of the skin
  32. runny nose
  33. seizures
  34. shivering
  35. sneezing
  36. stomach pain or tenderness
  37. sunken eyes
  38. swelling of the eyelids, face, lips, hands, or feet
  39. thirst
  40. trouble sleeping
  41. trouble swallowing
  42. vomiting
  43. weakness or heaviness of the legs
  44. wrinkled skin


  1. Blistering, peeling, or loosening of the skin
  2. bloating
  3. blue lips, fingernails, or skin
  4. chest pain, possibly moving to the left arm, neck, or shoulder
  5. constipation
  6. coughing that sometimes produces a pink frothy sputum
  7. difficult, noisy breathing
  8. indigestion
  9. irregular, fast or slow, or shallow breathing
  10. pains in the stomach, side, or abdomen, possibly radiating to the back
  11. puffiness or swelling of the eyelids or around the eyes, face, lips or tongue
  12. red, irritated eyes
  13. vomiting of blood or material that looks like coffee grounds
  14. yellow eyes or skin

Incidence not known

  1. Sudden, severe chest pain
  2. sudden weakness in arms or legs

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Back pain
  2. difficulty with moving
  3. lack or loss of strength
  4. muscle stiffness
  5. stuffy nose

Less common

  1. Blemishes on the skin
  2. burning feeling in the chest or stomach
  3. change in taste
  4. hearing loss
  5. loss of taste
  6. muscle cramping
  7. pimples
  8. ringing, buzzing, or other unexplained noise in the ears that continues
  9. stomach upset


  1. Flaking and falling off of the skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.