Mayo Clinic's approach to Wilms' tumor care

Mayo pediatric specialists discuss a Wilms' tumor patient.

A multispecialty team consisting of a pediatric urologist, pediatric surgeon and pediatric cancer specialists collaborate to determine a personalized treatment plan for a child with Wilms' tumor.

Mayo Clinic in Minnesota ranks among the Best Hospitals for urology in the U.S. News & World Report Best Hospitals rankings.

At Mayo Clinic Children's Center, you can expect the best care for your child from our multispecialty team of pediatric experts on Wilms' tumor.

Your Mayo Clinic care team

Mayo's experienced team of pediatric specialists work together to create a customized treatment plan for your child. Team members include pediatric urologists, pediatric oncologists, pediatric surgeons, pediatric anesthesiologists, radiation oncologists, radiologists, kidney pathologists, pediatric nurse practitioners, pediatric nurses, child life specialists, social workers and others as needed. Genetic testing and counseling are done when relevant.

Full range of treatment options

Mayo Clinic experts will work with you to review all of your child's treatment options. The range of treatments offered for children with Wilms' tumor includes surgery (partial or total nephrectomy), chemotherapy and radiation.

Access to the latest technology

When appropriate, Mayo Clinic offers minimally invasive surgery, which includes laparoscopic surgery and robotic surgery. Robotic surgery enables the surgeon to visualize the procedure in much greater detail and work in tight spaces where human hands don't fit. Mayo Clinic's new Proton Beam Therapy Program provides highly targeted precision beam therapy, destroying cancer while sparing healthy tissue.

Robotic surgery involves using a computer to control mechanical arms with surgical instruments attached.

In robotic surgery, the surgeon sits at a computer console near the operating table. He or she controls the camera arm and mechanical arms, which have surgical instruments attached to them that are working inside the patient's body.

Robotic surgery involves an assistant who makes sure the robotic arms move safely.

During robotic surgery, an assistant works at the operating table, exchanging instruments and ensuring the safe movement of the robotic arms.

Mayo Clinic offers proton beam therapy, a major advance in treating cancerous tumors, for patients who meet certain criteria.

Some children with Wilms' tumor may be candidates for Mayo Clinic's proton beam therapy, highly advanced technology that targets and destroys cancer while sparing healthy tissue.

Early-phase clinical trial opportunities

Mayo Clinic doctors are active in kidney cancer research, including Wilms' tumor, which gives patients a chance to enroll in clinical trials to try the latest treatment innovations.

Continuity of care

Mayo Clinic provides lifelong care, so children who have cancer can transition to adult care for follow-up as they age. This is especially important for those who had chemotherapy, to monitor for and treat any long-term effects.

Aug. 16, 2017
  1. Ritchey ML, et al. Pediatric urologic oncology: Renal and adrenal. In: Campbell-Walsh Urology. 11th ed. Philadelphia, Pa.: Elsevier; 2016. Accessed Jan. 13, 2017.
  2. Ferri FF. Nephroblastoma. In: Ferri's Clinical Advisor. Philadelphia, Pa.: Elsevier; 2017. Accessed Jan. 13, 2017.
  3. Kieran K, et al. Current surgical standards of care in Wilms tumor. Urologic Oncology: Seminars and Original Investigations. 2016;34:13.
  4. Al-Hussain T, et al. Wilms tumor: An update. Advances in Anatomic Pathology. 2014;21:166.
  5. Cost NG, et al. Oncologic outcomes of partial versus radical nephrectomy for unilateral Wilms tumor. Pediatric Blood & Cancer. 2012;58:898.
  6. Lubahn JD, et al. Correlation between preoperative staging computerized tomography and pathological findings after nodal sampling in children with Wilms tumor. Journal of Urology. 2012;188:1500.
  7. Cost NG, et al. Pathological review of Wilms tumor nephrectomy specimens and potential implications for nephron sparing surgery in Wilms tumor. Journal of Urology. 2012;188:1506.
  8. Wilms tumor. American Cancer Society. Accessed Jan. 13, 2017.
  9. Chintagumpala M, et al. Presentation, diagnosis, and staging of Wilms tumor. Accessed Jan. 14, 2017.
  10. Chintagumpala M, et al. Treatment and prognosis of Wilms tumor. Accessed Jan. 16, 2017.
  11. Children with cancer: A handbook for parents. National Cancer Institute. Accessed Jan. 16, 2017.
  12. AskMayoExpert. Wilms tumor. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2016.
  13. Granberg, CF (expert opinion). Mayo Clinic, Rochester, Minn. Mar. 1, 2017.
  14. Arndt CA (expert opinion). Mayo Clinic, Rochester, Minn. Feb. 1, 2017.
  15. National Library of Medicine. Your guide to understanding genetic conditions: Beckwith-Wiedemann syndrome. Genetics Home Reference: Accessed Feb. 2, 2017.