Primary sclerosing cholangitis (PSC)

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Displaying 1-5 out of 5 doctors available

Last Name Initial: L

  1. Nicholas F. LaRusso, M.D.

    Nicholas F. LaRusso, M.D.

    1. Internist
    2. Gastroenterologist
    1. Rochester, MN
    Areas of focus:

    Liver transplant, Upper endoscopy, Primary sclerosing cholangitis, Polycystic liver disease

  2. Konstantinos N. Lazaridis, M.D.

    Konstantinos N. Lazaridis, M.D.

    1. Gastroenterologist
    1. Rochester, MN
    Areas of focus:

    Primary sclerosing cholangitis, Primary biliary cholangitis, Liver cancer

  3. Michael D. Leise, M.D.

    Michael D. Leise, M.D.

    1. Transplant Hepatologist
    1. Rochester, MN
    Areas of focus:

    Colonoscopy, Upper endoscopy, Cholangiocarcinoma, Primary sclerosing cholangitis, Hereditary hemorrhagic telangiectasia..., Hepatitis C, Wilson's disease, Hepatitis B, Hepatocellular carcinoma, Primary biliary cholangitis, Nonalcoholic fatty liver disease, Cirrhosis, Autoimmune hepatitis, Alcoholic hepatitis, Hepatopulmonary syndrome, Hemochromatosis, Liver disease, Esophageal varices, Hepatic encephalopathy, Portal hypertension, Portopulmonary hypertension

  4. Jason T. Lewis, M.D.

    Jason T. Lewis, M.D.

    1. Pathologist
    1. Jacksonville, FL
    Areas of focus:

    Primary sclerosing cholangitis, Liver disease, Barrett's esophagus

  5. Nicole M. Loo, M.D.

    Nicole M. Loo, M.D.

    1. Internist
    2. Transplant Hepatologist
    1. Jacksonville, FL
    Areas of focus:

    Liver transplant, Pre-transplant evaluation, Post-transplant long-term care, Cholangiocarcinoma, Primary sclerosing cho...langitis, Hepatitis C, Hepatitis B, Hepatocellular carcinoma, Primary biliary cholangitis, Nonalcoholic fatty liver disease, Cirrhosis, Acute liver failure, Autoimmune hepatitis, Alcoholic hepatitis, Hepatopulmonary syndrome, Liver disease, Liver cancer, Hepatic encephalopathy, Fatty liver disease, Liver mass

Research

Mayo Clinic researchers were among the first to describe PSC. Other research done at Mayo has helped to refine diagnostic tests, improve treatment and assess the results of liver transplants for people with PSC.

Mayo Clinic researchers also developed mathematical models to help physicians predict long-term survival for people with PSC. Researchers at Mayo Clinic also advanced the use of the fluorescence in situ hybridization, also called FISH, test in the diagnosis of bile duct cancer in people with PSC.

Researchers at Mayo Clinic also are studying the DNA of people with PSC in hopes of identifying genes that increase the risk of the disease and predict its course. Basic research related to PSC and other liver diseases is conducted in the following Mayo Clinic laboratories:

Publications

See a list of publications about primary sclerosing cholangitis (PSC) by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles

By Mayo Clinic Staff

Primary sclerosing cholangitis (PSC) care at Mayo Clinic

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Diagnosis & treatmentCare at Mayo Clinic
Oct. 14, 2025
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Primary sclerosing cholangitis (PSC)

Research: It's all about patients

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Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight.