Lynch syndrome

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Departments and specialties

Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery.

Departments that treat this condition

Research

Mayo Clinic researchers are actively investigating new ways to identify and care for people with Lynch syndrome. They also are looking into new ways to prevent cancer.

Mayo Clinic doctors have made many important discoveries that have contributed to the improved care of people with Lynch syndrome. For example, Mayo Clinic researchers were among the first to recognize microsatellite instability (MSI) in cancer cells. Those researchers developed a microsatellite instability test to find Lynch syndrome in people with colon cancer. MSI testing helps identify which cancers are most likely to be caused by Lynch syndrome.

Publications

See a list of publications about Lynch syndrome by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles

By Mayo Clinic Staff

Lynch syndrome care at Mayo Clinic

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Diagnosis & treatmentCare at Mayo Clinic
Dec. 02, 2025
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Living with lynch syndrome?

Connect with others like you for support and answers to your questions in the Colorectal Cancer support group on Mayo Clinic Connect, a patient community.

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Lynch syndrome

Research: It's all about patients

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Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight.