Small studies seem to suggest that drinking pomegranate juice might lower cholesterol, but overall the evidence is mixed. It's thought that pomegranate juice might block or slow the buildup of cholesterol in the arteries of people who are at higher risk of heart disease.
Like many fruit juices, pomegranate juice contains antioxidants, especially polyphenols. Pomegranate juice contains antioxidants at higher levels than do many other fruit juices, and it contains nearly three times as many antioxidants as green tea or red wine does. Antioxidants are thought to provide several heart-protecting benefits, including reducing low-density lipoprotein (LDL, or "bad") cholesterol.
Pomegranate juice is generally safe to drink if you take some precautions. Check the label to be sure that you're drinking pure pomegranate juice, and not a mixture of juices that contains added sugar. The sugar adds more calories to the juice, which reduces its heart-health benefits.
As you should do with any herbal or dietary supplement, talk to your doctor about pomegranate juice before you start drinking it regularly as a supplement. Pomegranate juice may cause dangerous side effects when it interacts with certain prescription medications, such as the blood thinner warfarin (Coumadin, Jantoven) and angiotensin-converting enzyme (ACE) inhibitors, including captopril (Capoten), enalapril (Vasotec), lisinopril (Prinivil, Zestril) and ramipril (Altace).
Nov. 25, 2020
From Mayo Clinic to your inbox
Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health.
ErrorEmail field is required
ErrorInclude a valid email address
To provide you with the most relevant and helpful information, and understand which
information is beneficial, we may combine your email and website usage information with
other information we have about you. If you are a Mayo Clinic patient, this could
include protected health information. If we combine this information with your protected
health information, we will treat all of that information as protected health
information and will only use or disclose that information as set forth in our notice of
privacy practices. You may opt-out of email communications at any time by clicking on
the unsubscribe link in the e-mail.
Thank you for subscribing
Our Housecall e-newsletter will keep you up-to-date on the latest health information.
Sorry something went wrong with your subscription
Please, try again in a couple of minutes
See more Expert Answers
- Aviram M, et al. Pomegranate protection against cardiovascular diseases. Evidence-Based Complementary and Alternative Medicine: eCAM. 2012;2012:el.
- Pomegranate. Natural Medicines. https://naturalmedicines.therapeuticresearch.com. Accessed Sept. 20, 2017.
- AskMayoExpert. Pomegranate. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2017.
- Bauer BA (expert opinion). Mayo Clinic, Rochester, Minn. Sept. 20, 2017.
- Manthou E, et al. Effect of pomegranate juice consumption on biochemical parameters and complete blood count. Experimental and Therapeutic Medicine. 2017;14:1756.