Alpha-1-antitrypsin deficiency Care at Mayo Clinic
Nationally recognized expertise
Mayo Clinic in Jacksonville, Fla., is ranked among the Best Hospitals for digestive disorders by U.S. News & World Report. Research conducted at Mayo Clinic has produced new treatments of liver disease, IBD and many other GI conditions; new technologies to identify causes of irritable bowel syndrome and other motility disorders; and a new generation of endoscopic techniques to perform incision-free procedures for obesity and other complex GI conditions.
Mayo Clinic in Rochester, Minnesota, is ranked among the Best Hospitals for heart and heart surgery, gastroenterological surgery, neurosurgery and lung surgery by U.S. News & World Report. Mayo Clinic Children's in Rochester is ranked the No. 1 hospital in Minnesota and the five-state region of Iowa, Minnesota, North Dakota, South Dakota and Wisconsin, according to U.S. News & World Report's 2025–2026 "Best Children's Hospitals" rankings.
Locations, travel and lodging
Mayo Clinic has major campuses in Phoenix and Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota. The Mayo Clinic Health System has dozens of locations in several states.
For more information on visiting Mayo Clinic, choose your location below:





Costs and insurance
Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people.
In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.
Learn more about appointments at Mayo Clinic.
Please contact your insurance company to verify medical coverage and to obtain any needed authorization prior to your visit. Often, your insurer's customer service number is printed on the back of your insurance card.
More information about billing and insurance:
CON-20228281