The Center for Women's Health provides overarching support to the broad range of services available at Mayo Clinic's campus in Minnesota, including diagnostic breast services, heart care (cardiology), skin care (dermatology), nutrition and weight management, menopause and sexual health services, gynecology and urogynecology, integrative medicine and health, psychology and psychiatry, preventive health services, and predictive genomics.

Conditions treated include breast cancer, endometrial cancer, female infertility, fibromyalgia, inflammatory bowel disease, lupus, menopause, migraine, multiple sclerosis, non-alcoholic fatty liver disease, obesity, osteoporosis, ovarian cancer, sexual health concerns, sudden coronary artery dissection and thyroid cancer.