General Internal Medicine

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. A Study to Evaluate Sex and Age Differences in Ehlers Danlos Syndrome Patients

   Jacksonville, Fla.

   The purpose of this study is to determine whether serum biomarkers and comorbidities differ between subjects with hEDS/HSD vs. other non-hypermobile EDS subtypes and whether sex and/or age differences exist, and to determine whether serum biomarkers and comorbidities differ between subjects with hEDS vs. HSD and whether sex and/or age differences exist.

2. A Study to Evaluate Factors in Breast Cancer Screening Among Asian Americans in Olmsted and Surrounding Counties

   Rochester, Minn.

   The purpose of this study is to assess the effect of acculturation, socio-economic status (SES) and place of residence (urban vs. rural) on the level of participation in breast cancer screening programs and on the breast cancer knowledge and beliefs among Asian American women in Olmsted and surrounding counties.

3. A Study to Analyze Potential Long-term Treatments for Covid-19 Recovery

   Scottsdale/Phoenix, Ariz., Rochester, Minn.

   This study aims to further understand the extent of long term effects of COVID-19 via batteries of self-assessment questionnaires focused on the most common complications of SARS-COVID 19 infections including respiratory and cardiovascular symptoms, frailty, fatigue, exercise capacity, cognitive and emotional functionality, and overall quality of life. Furthermore, we will investigate the impact of 4 weeks of respiratory muscle training and nasal breathing on the above mentioned long-term Covid-19 disease complications.

    

4. A Study to Assess Markers of Aging Process

   Rochester, Minn.

   The purose of this study is to develop assays to identify markers related to aging processes in a variety of biospecimens, including but limited to blood, urine, saliva, buccal swabs, cerebrospinal fluid, tissue, etc. 

   ***Not enrolling for cohort 2 at this time.

5. Alleviation by Fisetin of Frailty, Inflammation, and Related Measures in Older Women

   Rochester, Minn.

   The purpose of this study is test the effectiveness of the senolytic drug (Fisetin) in reducing senescent cell abundance in blood in elderly adults.

    

    

6. A Study to Determine the Effect of Distance Reiki on Patient Reported Quality of Life (PRQoL) and Immunity Among Multiple Myeloma Patients

   Rochester, Minn.

   This study aims to demonstrate acceptability and feasibility of the use of Distance Reiki therapy versus sham Reiki therapy among multiple myeloma patients.It also aims to determine if there is a minimal clinically meaningful improvement in various QOL domains (Physical, Social, Emotional), overall QOL with use of Patient-Reported Outcomes Measurement Information System (PROMIS-29) and Single Item Linear Analogue Scale (LASA) after Distance Reik. Lastly, it aims to analyze the effect of Distance Reiki on expansion of the immune repertoire by comparing immune repertoires at baseline and at the end of the study by using Mass spectrometry by CyTOF® and  multiplex polymerase chain reaction (PCR) sequencing of the T-cell receptors (TCRs) for assessment of immune repertoire diversity by iRepertoire®.

7. A Study to Assess Reproductive History in Kidney Donors

   Rochester, Minn., Scottsdale/Phoenix, Ariz.

   The purpose of this study is to analyze the effect of parity, menopause and reproductive lifespan on kidney structure and function.

8. A Study to Evaluate Patient Perspectives of Vaginal Bleeding During the Menopause Transition and Future Innovations Addressing Changes in Vaginal Bleeding Patterns

   Jacksonville, Fla.

   The primary purpose of this study is to assess how women within different stages of menopause perceive menstrual bleeding changes during the menopause transition within the outpatient gynecology practice.

    

9. Evaluation of the Effects of Caffeine, Via the ACE2 Receptor, on Clinical Severity of COVID-19 Disease

   Jacksonville, Fla.

   The purpose of this study is to assess levels of caffeine intake among patients who tested positive for COVID-19 infection and compare that to disease severity.

10. The Effect of Aromatherapy on Stress, Anxiety, and Well-being in GIM Allied Health Medical Secretary, Administrative, and Scheduling Staff During the Covid-19 Pandemic

    Rochester, Minn.

    The purpose of this study is to determine if aromatherapy has a positive effect on increasing perceived well-being and decreases stress and anxiety while working from home during the COVID-19 pandemic.