Medicina interna general

A continuación se enumeran ensayos clínicos actuales.

Filtrar esta lista de estudios según la ubicación, el estado del estudio y más.

1. A Study to Enroll Patients of Rheumatic Diseases and First-degree Relatives in a Biobank

   Rochester, Minn.

   The purpose of this study is to enroll rheumatic disease patients and first-degree relatives in a biobank, and to follow them over time to assess health outcomes and collect additional specimens.

2. Cardiovascular Effects of Adderall in Healthy Young Adults

   Rochester, Minn.

   The purpose of this study is to determine blood pressure and heart rate changes (hemodynamic changes) in healthy adults after taking one dose of prescription medication Adderall 25 mg orally, and comparing the results to those of  a placebo pill. 

3. A Study to Assess Bone Quality Characteristics, Comparing Type 2 Diabetes Patients who have or have not had Prior Fragile Bone Fractures

   Rochester, Minn.

   The purpose of this study is to assess key characteristics of bone quality, specifically material strength and porosity, in patients who have type 2 diabetes. These patients are at an unexplained increased risk for fractures and there is an urgent need to refine clinical assessment for this risk.

4. A Study of Mechanisms of Altered Ventilatory Control in Heart Failure

   Rochester, Minn.

   This study is being done because the investigators are trying to understand how feedback from the muscles can influence your blood pressure and breathing during exercise, and if the investigators can reduce this response in heart failure patients. The investigators are also trying to determine ways to improve tolerance to exercise in heart failure patients.

5. A Study Comparing Standard Treatment versus Accelerated Initiation of Renal Replacement Therapy for Acute Kidney Injury

   Rochester, Minn.

   The purpose of this study is to determine if, in critically ill patients with severe acute kidney injury, an earlier start of renal replacement therapy compared to standard treatment will lead to improved survival and recovery of kidney function.

6. Sapanisertib in Treating Patients With Relapsed and/or Refractory Acute Lymphoblastic Leukemia

   Rochester, Minn., Scottsdale/Phoenix, Ariz., Jacksonville, Fla.

   This phase II trial studies how well sapanisertib works in treating patients with acute lymphoblastic leukemia that has returned after a period of improvement (relapsed) or has not responded to previous treatment (refractory). Sapanisertib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.

7. A Study of the Safety and Effectiveness of Ceritinib Combined with Nivolumab for Patients with ALK-Positive Non-Small Cell Lung Cancer

   Scottsdale/Phoenix, Ariz.

   The purpose of this study is to determine the safety and effectiveness of ceritinib when combined with nivolumab for anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer patients.

8. A Study Testing the Philips Scanner Technology for Reliable Respiratory Assessment

   Rochester, Minn.

   The purpose of this study is to test the Philips Camera bar code scanner with actual patients, to assess its effectiveness in measuring breaths inspite of common obstructions.

9. Evaluate the Effect of ALLN-177 in Reducing Urinary Oxalate in Patients With Secondary Hyperoxaluria and Kidney Stones Over 28 Days

   Rochester, Minn.

   Evaluate the safety, tolerability, and efficacy of 28 days of treatment with ALLN-177 for reducing urinary oxalate excretion in patients with secondary hyperoxaluria and kidney stones.

10. A Study to Determine the Microbial Population of the Intestines in Patients with Active or Treated Inactive Eosinophilic Esophagitis

    Rochester, Minn.

    The purpose of this study is to collect stool samples and determine the intestine microbe environment in patients who have active or treated inactive eosinophilic esophagitis.

A continuación se enumeran ensayos clínicos actuales.

Filtrar esta lista de estudios según la ubicación, el estado del estudio y más.

1. A Study to Assess Bone Quality Characteristics, Comparing Type 2 Diabetes Patients who have or have not had Prior Fragile Bone Fractures

   Rochester, Minn.

   The purpose of this study is to assess key characteristics of bone quality, specifically material strength and porosity, in patients who have type 2 diabetes. These patients are at an unexplained increased risk for fractures and there is an urgent need to refine clinical assessment for this risk.

2. A Study to Enroll Patients of Rheumatic Diseases and First-degree Relatives in a Biobank

   Rochester, Minn.

   The purpose of this study is to enroll rheumatic disease patients and first-degree relatives in a biobank, and to follow them over time to assess health outcomes and collect additional specimens.

3. Cardiovascular Effects of Adderall in Healthy Young Adults

   Rochester, Minn.

   The purpose of this study is to determine blood pressure and heart rate changes (hemodynamic changes) in healthy adults after taking one dose of prescription medication Adderall 25 mg orally, and comparing the results to those of  a placebo pill. 

4. A Study of Mechanisms of Altered Ventilatory Control in Heart Failure

   Rochester, Minn.

   This study is being done because the investigators are trying to understand how feedback from the muscles can influence your blood pressure and breathing during exercise, and if the investigators can reduce this response in heart failure patients. The investigators are also trying to determine ways to improve tolerance to exercise in heart failure patients.

5. A Study Comparing Standard Treatment versus Accelerated Initiation of Renal Replacement Therapy for Acute Kidney Injury

   Rochester, Minn.

   The purpose of this study is to determine if, in critically ill patients with severe acute kidney injury, an earlier start of renal replacement therapy compared to standard treatment will lead to improved survival and recovery of kidney function.

6. Sapanisertib in Treating Patients With Relapsed and/or Refractory Acute Lymphoblastic Leukemia

   Rochester, Minn., Scottsdale/Phoenix, Ariz., Jacksonville, Fla.

   This phase II trial studies how well sapanisertib works in treating patients with acute lymphoblastic leukemia that has returned after a period of improvement (relapsed) or has not responded to previous treatment (refractory). Sapanisertib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.

7. A Study of the Safety and Effectiveness of Ceritinib Combined with Nivolumab for Patients with ALK-Positive Non-Small Cell Lung Cancer

   Scottsdale/Phoenix, Ariz.

   The purpose of this study is to determine the safety and effectiveness of ceritinib when combined with nivolumab for anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer patients.

8. A Study Testing the Philips Scanner Technology for Reliable Respiratory Assessment

   Rochester, Minn.

   The purpose of this study is to test the Philips Camera bar code scanner with actual patients, to assess its effectiveness in measuring breaths inspite of common obstructions.

9. Evaluate the Effect of ALLN-177 in Reducing Urinary Oxalate in Patients With Secondary Hyperoxaluria and Kidney Stones Over 28 Days

   Rochester, Minn.

   Evaluate the safety, tolerability, and efficacy of 28 days of treatment with ALLN-177 for reducing urinary oxalate excretion in patients with secondary hyperoxaluria and kidney stones.

10. A Study to Determine the Microbial Population of the Intestines in Patients with Active or Treated Inactive Eosinophilic Esophagitis

    Rochester, Minn.

    The purpose of this study is to collect stool samples and determine the intestine microbe environment in patients who have active or treated inactive eosinophilic esophagitis.