A menudo, Mayo Clinic realiza estudios clínicos sobre diversos temas relacionados con la atención médica general y en varios estados, como en Minnesota, Florida y Arizona.
A continuación se enumeran ensayos clínicos actuales.
317 estudios en Medicina interna general (estudios abiertos únicamente).
Filtrar esta lista de estudios según la ubicación, el estado del estudio y más.
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Rochester, Minn.
The purpose of this study is to look for ways to test how muscle tissue differs between people.
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Rochester, Minn.
The purpose of this study is to determine blood pressure and heart rate changes (hemodynamic changes) in healthy adults after taking one dose of prescription medication Adderall 25 mg orally, and comparing the results to those of a placebo pill.
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Rochester, Minn.
The purpose of this research study is to gather information on the feasibility of performing novel molecular analysis on Endoscopic Ultrasound acquired cytologic material and to assess molecular changes in cytology samples to see if that may aid treatment decision planning for future patients.
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Scottsdale/Phoenix, Ariz.
This pilot phase II trial studies P1101 (polyethyleneglycol [PEG]-proline-interferon alpha-2b) in treating patients with early myelofibrosis. PEG-proline-interferon alpha-2b is a substance that can improve the body's natural response and may slow the growth of early myelofibrosis.
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Rochester, Minn.
The purpose of this study is to measure and identify chest fluid volumes associated with heart failure and to determine their impact on lung structure and function, and also assess the effect of body position on shifts in fluid and the effects of this on lung function, mechanics and gas exchange.
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Rochester, Minn.
The purpose of this study is to enroll rheumatic disease patients and first-degree relatives in a biobank, and to follow them over time to assess health outcomes and collect additional specimens.
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Rochester, Minn., La Crosse, Wis., Red Wing, Minn., Mankato, Minn., Cannon Falls, Minn., Albert Lea, Minn., Austin, Minn.
Participants with heart failure with preserved ejection fraction will undergo 12 weeks of cardiac rehabilitation for exercise training (ET) and be randomized to either nebulized sodium nitrite inhalation solution or placebo inhalation solution (normal saline) through the training period. Study drug is administered 3 times daily during daytime hours with one of these doses being immediately prior to onset of ET sessions throughout the 12 week trial. The objective is to determine if the inhaled sodium nitrite improves the clinical responses and tolerability of ET.
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Rochester, Minn.
A variety of liver insults lead to pathological changes in liver architecture that culminate in cirrhosis. While invasive liver biopsy was required to detect cirrhosis, the development of magnetic resonance elastography (MRE) has revolutionized our ability to detect liver fibrosis through non-invasive means that involve measurement of liver stiffness. However, a number of pathological findings occur in liver in response to various insults that precede cirrhosis and are clinically important to identify such as steatosis associated with NASH, inflammation associated with viral hepatitis, and congestion associated with cardiac hepatopathy. Detection of such entities provides essential diagnostic, prognostic, and treatment information but yet is not available non-invasively. Recent murine studies from this group of investigators has identified that MRE technology can be adapted to non-invasively detect these conditions. Implementing this into the practice will transform it by obviating the need for invasive liver biopsies in patients suspected of having such forms of suspected liver disease. This will differentiate Mayo from other institutions where such technology is not available.
An additional aim of this study is to examine the impact of obstructive sleep apnea (OSA) on the pathogenesis of nonalcoholic fatty liver disease (NAFLD), both common comorbidities of obesity. Recent evidence indicates a potential link between OSA and severity of NASH and fibrosis, but the mechanisms of OSA- associated hypoxia on liver disease progression in NAFLD is unclear. This study offers the unique opportunity to analyze this association, as the study population will undergo routine evaluation for OSA, as part as the preoperative work-up prior to bariatric surgery.
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Rochester, Minn.
Are we able to use the EPO staining technique using the sponge ?
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Rochester, Minn.
The overarching goal of the FMT registry is to expand knowledge and optimize practice in the transplantation of fecal microbiota or other gut-related-microbiota products.
June 11, 2020
A continuación se enumeran ensayos clínicos actuales.
317 estudios en Medicina interna general (estudios abiertos únicamente).
Filtrar esta lista de estudios según la ubicación, el estado del estudio y más.
-
Rochester, Minn.
The purpose of this study is to look for ways to test how muscle tissue differs between people.
-
Rochester, Minn.
The purpose of this study is to determine blood pressure and heart rate changes (hemodynamic changes) in healthy adults after taking one dose of prescription medication Adderall 25 mg orally, and comparing the results to those of a placebo pill.
-
Rochester, Minn.
The purpose of this research study is to gather information on the feasibility of performing novel molecular analysis on Endoscopic Ultrasound acquired cytologic material and to assess molecular changes in cytology samples to see if that may aid treatment decision planning for future patients.
-
Scottsdale/Phoenix, Ariz.
This pilot phase II trial studies P1101 (polyethyleneglycol [PEG]-proline-interferon alpha-2b) in treating patients with early myelofibrosis. PEG-proline-interferon alpha-2b is a substance that can improve the body's natural response and may slow the growth of early myelofibrosis.
-
Rochester, Minn.
The purpose of this study is to measure and identify chest fluid volumes associated with heart failure and to determine their impact on lung structure and function, and also assess the effect of body position on shifts in fluid and the effects of this on lung function, mechanics and gas exchange.
-
Rochester, Minn.
The purpose of this study is to enroll rheumatic disease patients and first-degree relatives in a biobank, and to follow them over time to assess health outcomes and collect additional specimens.
-
Rochester, Minn., La Crosse, Wis., Red Wing, Minn., Mankato, Minn., Cannon Falls, Minn., Albert Lea, Minn., Austin, Minn.
Participants with heart failure with preserved ejection fraction will undergo 12 weeks of cardiac rehabilitation for exercise training (ET) and be randomized to either nebulized sodium nitrite inhalation solution or placebo inhalation solution (normal saline) through the training period. Study drug is administered 3 times daily during daytime hours with one of these doses being immediately prior to onset of ET sessions throughout the 12 week trial. The objective is to determine if the inhaled sodium nitrite improves the clinical responses and tolerability of ET.
-
Rochester, Minn.
A variety of liver insults lead to pathological changes in liver architecture that culminate in cirrhosis. While invasive liver biopsy was required to detect cirrhosis, the development of magnetic resonance elastography (MRE) has revolutionized our ability to detect liver fibrosis through non-invasive means that involve measurement of liver stiffness. However, a number of pathological findings occur in liver in response to various insults that precede cirrhosis and are clinically important to identify such as steatosis associated with NASH, inflammation associated with viral hepatitis, and congestion associated with cardiac hepatopathy. Detection of such entities provides essential diagnostic, prognostic, and treatment information but yet is not available non-invasively. Recent murine studies from this group of investigators has identified that MRE technology can be adapted to non-invasively detect these conditions. Implementing this into the practice will transform it by obviating the need for invasive liver biopsies in patients suspected of having such forms of suspected liver disease. This will differentiate Mayo from other institutions where such technology is not available.
An additional aim of this study is to examine the impact of obstructive sleep apnea (OSA) on the pathogenesis of nonalcoholic fatty liver disease (NAFLD), both common comorbidities of obesity. Recent evidence indicates a potential link between OSA and severity of NASH and fibrosis, but the mechanisms of OSA- associated hypoxia on liver disease progression in NAFLD is unclear. This study offers the unique opportunity to analyze this association, as the study population will undergo routine evaluation for OSA, as part as the preoperative work-up prior to bariatric surgery.
-
Rochester, Minn.
Are we able to use the EPO staining technique using the sponge ?
-
Rochester, Minn.
The overarching goal of the FMT registry is to expand knowledge and optimize practice in the transplantation of fecal microbiota or other gut-related-microbiota products.