Critical Care

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. A Study to Assess Physician Preferences for Electronic Chart Review and Historical Information Needs for New Patient Encounters in the ICU

   Rochester, Minn.

   The purpose of this study is to develop an interactive medical record timeline based on physician preferences and perceived clinical needs, to improve the chart review process for new patient encounters in the ICU.

2. Real Time Detection of Electrophysiologic Disturbances Following Subdural Hematoma Evacuation

   Rochester, Minn.

   The purpose of this study is to detect and characterizer electrophysiologic disturbances (such as local field potentials) in patients with underrecognized cause of coma, focal deficits and prolonged encephalopathy following subdural hematoma (SDH) evacuation.

3. Study to Compare Electrical and Ultrasonographic Evaluation of the Phrenic Nerve-Diaphragm Neuromuscular Junction (NMJ) Function

   Jacksonville, Fla.

   The purpose of this study is to ensure technical success in the treatment of assessing diaphragmatic neuromuscular junction (NMJ) function of the diaphragm in normal patients.

4. Training of Physicians in Critical Care Ultrasonography (CCUS)

   Rochester, Minn.

   The purpose of this study is to assess the improvement in physician’s knowledge and skill sets in ultrasonography after the implementation of simulation-based educational program.  

5. Study of the Incidence of Electrographic Status Epilepticus and Seizures of PICU Patients at National Children’s Hospital in Hanoi, Vietnam.

   Rochester, Minn.

   The purpose of the study is:

   1. To determine the incidence of subclinical electrographic seizures and electrographic status epilepticus in children admitted to the PICU for head trauma, traumatic brain injury (TBI), and/or child abuse at National Children’s Hospital in Hanoi, Vietnam.

   2. To determine whether a correlation exists between length of stay, morbidity, and mortality with incidence of subclinical SE and seizures.

6. A Study to Compare High Versus Low Bicarbonate Bath in Critically-ill Patients Receiving Continuous Renal Replacement Therapy

   Rochester, Minn.

   The purpose of this study is to investigate the effect of using high versus low bicarbonate containing replacement fluid in patients with metabolic acidosis receiving continuous renal replacement therapy (CRRT) with veno-venous hemofiltration (CVVH) for acute kidney injury (AKI) on in-hospital mortality.

7. A Pilot Study Examining Thiamine Deficiency in Patients Admitted to the Hospital for Liver Transplantation

   Jacksonville, Fla.

   The purpose of this study is to report the proportion of thiamine deficiency (as defined by the Mayo Clinic Laboratory reference range) in liver transplant patients.

8. Study to Determine Safety and Effectiveness of Ascorbic Acid, Corticosteroids, and Thiamine in Treating Sepsis and Septic Shock

   Scottsdale/Phoenix, Ariz.

   The purpose of this study is to determine whether the combination of Ascorbic Acid (Vitamin C), Thiamine (Vitamin B1), and Corticosteroids improves the trajectory of organ failure and reduces mortality in patients with sepsis and septic shock as compared to placebo.

9. Study of Clinical Variables and Serum Anti-RSV Titer Before and After Administration of Polyclonal Immunoglobulin with High-Titer RSV Immunoglobulin

   Rochester, Minn.

   The purpose of this study is to assess the effect of administration of polyclonal immunoglobulin with high-titer respiratory syncytial virus (RSV) immunoglobulin (RI-002, ADMA Biologics) in relation to clinical variables,
   serum anti-RSV titer and RSV type and palivizumab sensitivity.