Cardiovascular Medicine

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. Is Our Microbiome a Predictor of Cardiac Risk

   Rochester, Minn.

   The purpose of this study is to compare the fecal microbiota of patients with mild, moderate and severe Coronary Artery Disease (CAD) by collecting stool and blood samples from patients undergoing coronary angiograms.

    

2. Genotype-Phenotype Correlation in Cardiovascular Disease

   Rochester, Minn.

   This research study is being done to help characterize cardiovascular disease and improve diagnostic tests.

   OBJECTIVES

   1. To understand the pathogenesis, molecular mechanisms, and disease progression of heritable cardiovascular disease

   2. To evaluate the incidence of occult heritable cardiovascular disease in various populations.

   3. To correlate imaging and pathological phenotype with genotype to the ends described above.

3. A Study to Assess the Role of Biomarkers in Risk Stratification in Adults with Congenital Heart Disease

   Rochester, Minn.

   The purporse of this study is to determine if biomarker assay obtained at baseline can predict future risk of cardiovascular adverse events, and to  determine if temporal changes in biomarker levels can provide a better risk prediction compared to biomarker assay obtained at baseline.

4. A Study to Evaluate Potential Myocardial Injury Following Magnetic Resonance Imaging (MRI)

   Rochester, Minn.

   The purpose of this study is to prospectively determine if magnetic resonance imaging (MRI) in patients with cardiac implantable electronic devices (CIED) results in myocardial injury as assessed by changes in high sensitivity cardiac troponin T (hs-cTnT) assay. This will be done by comparing pre-and-post MRI hs-cTnT levels in these patients.

5. Echocardiographic Measures of Pulmonary Vascular Distensibility and Effects on Lung Diffusing Capacity

   Rochester, Minn.

   The purpose of this study is to determine if the change in pulmonary vascular compliance with positional changes (upright, supine, and Trendelenburg position) is different in younger versus older individuals.

6. Peripheral Nerve Stimulation Therapy for Atrial Fibrillation

   Rochester, Minn.

   The purpose of this study is to determine and compare the safety and efficacy of transcutaneous afferent patterned stimulation (TAPS) and respiratory-gated auricular vagal afferent nerve stimulation (RAVANS) therapies for the reduction of paroxysmal atrial fibrillation (AF) burden.

7. A Study to Analyze Association of Frequent Premature Ventricular Complex with Stroke or Transient Ischemic Attack

   Rochester, Minn.

   The purpose of this study is to verify that high Premature Ventricular Complex (PVC) burden is associated with increased risk of stroke and/or Transient Ischemic Attack (TIA), to examine outcomes such as stroke/TIA, atrial fibrillation/flutter, and all-cause mortality associated with PVCs, and to evaluate whether PVCs are associated with development of appendage dysfunction.

8. A Study of the Effect of Myectomy on the Sudden Cardiac Death Risk in Hypertrophic Cardiomyopathy

   Rochester, Minn.

   The primary purpose/objective of this study is to determine whether myectomy as a management option for severe hypertrophic cardiomyopathy (HCM) reduces the incidence of sudden cardiac death.

9. Predictive Role of Non-Invasive Glucose Assessment During Pregnancy

   Rochester, Minn.

   This study aims to determine the value of regular, non-invasive [glucose] LabClasp monitoring during pregnancy.

10. A Study to Evaluate the Burden of Treatment and Illness in Advanced Heart Failure Patients

    Rochester, Minn.

    The primary purpose of this study is to identify which aspects of treatment are most prevalent and burdensome to patients with advanced heart failure.