Cardiovascular Medicine

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. Surgical Outcomes of Mitral Valve Repair

   Rochester, Minn.

   The purpose of this study is to learn more about early and late outcomes in patients after mitral valve repair.

2. Respiratory Muscle Contribution to Blood Pressure During Exercise

   Rochester, Minn.

   The investigators seek to understand how reflexes from the breathing muscles influence blood pressure during exercise. Furthermore, the investigators are determining if increasing breathing muscle strength (via inspiratory muscle training) influences the respiratory muscle contribution to blood pressure during exercise.

3. A Study to Identify the Self-Sustaining Core Causing Atrial Fibrillation, by Using Electrograms of Atrial and Ventricular Fibrillation to Calculate Wave Changes as Contractions Pass Through the Heart Muscle

   Rochester, Minn., Scottsdale/Phoenix, Ariz.

   The purpose of this study is to develop a new technique based on the change in wave pattern as it passes through muscle tissue, to estimate the location of the self-sustaining regions of chaotic rhythms like human Atrial Fibrillation (AF).

4. Study to Assess the Decline in Cognitive Function Using Standardized Neurocognitive Assessment in Atrial Fibrillation Patients Treated with Apixaban Versus Warfarin

   Rochester, Minn.

   The purpose of this study is to assess the decline in cognitive function using standardized neurocognitive assessment in Atrial Fibrilation patients treated with Apixaban vs Warfarin.

5. Vascular Diseases Biorepository

   Rochester, Minn.

   The eventual goal of this study is to identify genetic and proteomic markers that may influence susceptibility to vascular diseases including peripheral arterial disease, pulmonary hypertension, carotid artery stenosis, arterial aneurysmal disease, fibromuscular dysplasia, congenital heart disease and other less common diseases that affect the blood vessels.

6. Is Our Microbiome a Predictor of Cardiac Risk

   Rochester, Minn.

   The purpose of this study is to compare the fecal microbiota of patients with mild, moderate and severe Coronary Artery Disease (CAD) by collecting stool and blood samples from patients undergoing coronary angiograms.

    

7. Complex Aortic Aneurysm Repair With Fenestrated Stent Grafts

   Rochester, Minn.

   This study will compare two groups of subjects with complex abdominal aortic aneurysms. It will compare their clinical outcomes and quality of life measures. The group being treated in this study will have their aneurysms repaired by an endovascular approach using Zenith® Fenestrated AAA Endovascular Graft. This group will be compared to a group of 461 patients (historical cohort) whose complex aneurysms were treated by open surgical repair.

8. Mayo Clinic Cardiac Implantable Electronic Device MRI Registry

   Rochester, Minn.

   Registry intends to prospectively collect data regarding the safety of magnetic resonance imaging (MRI) studies in patients with cardiac pacemakers on implantable cardioverter defibrillators.

9. A Study of Mechanisms of Altered Ventilatory Control in Heart Failure

   Rochester, Minn.

   This study is being done because the investigators are trying to understand how feedback from the muscles can influence your blood pressure and breathing during exercise, and if the investigators can reduce this response in heart failure patients. The investigators are also trying to determine ways to improve tolerance to exercise in heart failure patients.

10. A Study Testing the Philips Scanner Technology for Reliable Respiratory Assessment

    Rochester, Minn.

    The purpose of this study is to test the Philips Camera bar code scanner with actual patients, to assess its effectiveness in measuring breaths inspite of common obstructions.