Cardiovascular Medicine

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. Respiratory Muscle Contribution to Blood Pressure During Exercise

   Rochester, Minn.

   The investigators seek to understand how reflexes from the breathing muscles influence blood pressure during exercise. Furthermore, the investigators are determining if increasing breathing muscle strength (via inspiratory muscle training) influences the respiratory muscle contribution to blood pressure during exercise.

2. A Study Testing the Philips Scanner Technology for Reliable Respiratory Assessment

   Rochester, Minn.

   The purpose of this study is to test the Philips Camera bar code scanner with actual patients, to assess its effectiveness in measuring breaths inspite of common obstructions.

3. A Study of the Mayo Clinic College of Medicine Ultrasound System

   Rochester, Minn.

   The purpose of this study is is to assess the EPIQ-Affiniti and NG Compact ultrasound systems in a clinical environment and collect clinical data and feedback when compared to the site’s standard ultrasound system.

4. Study to Assess the Decline in Cognitive Function Using Standardized Neurocognitive Assessment in Atrial Fibrillation Patients Treated with Apixaban Versus Warfarin

   Rochester, Minn.

   The purpose of this study is to assess the decline in cognitive function using standardized neurocognitive assessment in Atrial Fibrilation patients treated with Apixaban vs Warfarin.

5. A Study to Determine the Impact of Individualized Estrogen Therapy on Cardiovascular Disease Risk Parameters in Young Women after Bilateral Oophorectomy

   Rochester, Minn.

   The purpose of this study is to compare the cardiovascular function in young women (<46 years) following bilateral oophorectomy who are treated with either the standard dose of estradiol (100 mcg transdermal patch or equivalent oral dose) or titrated estradiol dosing to achieve average premenopausal estradiol level (80-120 pg/ml), to characterize the relationship between the serum estradiol level and cardiovascular function in young women (<46 years) on estradiol replacement after bilateral oophorectomy, and to compare the body composition in young women following bilateral oophorectomy who are treated with either the standard dose of estradiol (100 mcg transdermal patch or equivalent oral dose) or titrated estradiol dosing to achieve average premenopausal estradiol level (80-120 pg/ml).

6. A Study to Analyze Oxygen Consumption and Cardiac Output Measurements in Postural Orthostatic Tachycardia Syndrome

   Rochester, Minn.

   The purpose of this study is to describe the cardiac output and a-v O2 difference responses during cardiopulmonary exercise testing.

7. Study to Provide Normal Reference Values for Cardiac Magnetic Resonance Elastography

   Rochester, Minn.

   The purpose of this study is to provide normal reference values for cardiac magnetic resonance elastography.

8. A Study to Evaluate Home Monitoring of Post-Discharge Congestive Heart Failure Patients

   Rochester, Minn.

   The primary purpose of this study is to collect long-term (2-month duration) data with the ADI CHF Device on patients at home to demonstrate effectiveness of the device in accurately measuring biologically relevant parameters and detecting fluid status as compared to the standard of care (weight scale).

9. Assessment of the QT Interval Using a Smartphone ECG Device during Antiarrhythmic Drug Initiation

   Rochester, Minn.

   1. Obtain AliveCor ECG Recordings from subjects at the time of clinically indicated ECGs over the course their anti-arrhythmic drug loading hospital admission. 
   2. Create and refine an AliveCor algorithm to accurately measure a patient’s QT interval and heart rate corrected QTc value and validate/compare the results against the 12- lead ECGs on record.
   3. Obtain AliveCor ECG recordings at the time of daily clinically indicated electrolyte panels to further develop and refine a Potassium screening algorithm.

10. Complex Aortic Aneurysm Repair With Fenestrated Stent Grafts

    Rochester, Minn.

    This study will compare two groups of subjects with complex abdominal aortic aneurysms. It will compare their clinical outcomes and quality of life measures. The group being treated in this study will have their aneurysms repaired by an endovascular approach using Zenith® Fenestrated AAA Endovascular Graft. This group will be compared to a group of 461 patients (historical cohort) whose complex aneurysms were treated by open surgical repair.