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Christopher V. DeSimone, M.D., Ph.D.

  1. Cardiac Electrophysiologist
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Departments

Specialty Groups

Location

  1. Rochester, Minnesota

Languages

English

Existing patients

Appointments

  1. Atrial fibrillation
  2. Atrial flutter
  3. Atrial tachycardia
  4. Atypical atrial flutter
  5. AV nodal reentry tachycardia
  6. Orthodromic AV re-entrant tachycardia
  7. Post-surgical atrial arrhythmia
  8. Premature ventricular contractions
  9. Supraventricular tachycardia
  10. Ventricular tachycardia
  11. Wolff-Parkinson-White syndrome
  1. Cardiac ablation
  2. Cryotherapy
  3. EP study
  4. Intracardiac echocardiography
  5. Pulsed field ablation
  6. Radiofrequency ablation
  • Cardiac anatomy and relationship to arrhythmogenesis and ablation
  • Cardiac device related infections
  • Cardiac electrophysiology
  • Cardiac electroporation ablation for atrial and ventricular arrhythmias
  • Cardiac ion channel electrophysiology and drug interaction
  • Complex recurrent atypical flutter
  • Electroporation
  • General cardiology
  • Human clinical trials
  • Post-CryoMAZE atypical flutter
  • Purkinje network modulation for ventricular arrhythmia treatment and prevention
  • Pulsed Field Ablation
  • Translational innovation in cardiology
  1. 2019
    SubSpec FellowRST Clinical Cardiac Electroph, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  2. 2017
    FellowCardiovascular Diseases Training Program, Mayo Graduate School of Medicine, Mayo Clinic College of Medicine
  3. 2017
    FellowCardiovascular Disease, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  4. 2013
    ResidentInternal Medicine Residency Program, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  5. 2013
    ResidentInternal Medicine, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  6. 2010
    MD/PhD - Medicine; PhysiologyMedical Scientist Training Program, School of Medicine and Biomedical Sciences, State University of New York College at Buffalo
  7. 2003
    BS - Biochemistry and Biology Honors Program Summa Cum Laude with University HonorsNiagara University

Certifications

  1. 2020
    Clinical Cardiac ElectrophysiologyAmerican Board of Internal Medicine
  2. 2017
    Cardiovascular DiseasesAmerican Board of Internal Medicine

Awards and honors

  1. 2025
    2025 Mayo Clinic Experience Top Performer AwardMayo Clinic Patient Experience
  2. 2024
    2024 Mayo Clinic Experience Top Performer AwardMayo Clinic Patient Experience
  3. 2023
    2023 Mayo Clinic Experience Top Performer AwardMayo Clinic Patient Experience
  4. 2022
    2022 Mayo Clinic Experience Top Performer AwardMayo Clinic Patient Experience
  5. 2021
    2021 Mayo Clinic Experience Top Performer AwardMayo Clinic Patient Experience
  6. 2020
    Career Development Award in Cardiovascular Disease Research Honoring Dr. Earl H. Wood Department of Cardiovascular Medicine
  7. 2020
    2020 Provider Recognition AwardMayo Clinic Patient Experience
  8. 2020
    2020 Top Performing Provider in ExperienceMayo Clinic Patient Experience
  9. 2017
    Mayo Clinic Cardiovascular Medicine Outstanding Research Fellow AwardDepartment of Cardiovascular Medicine
  10. 2017
    Mayo Brothers Distinguished Fellow AwardDepartment of Cardiovascular Medicine
  11. 2015
    Cardiovascular Division Nominee; Donald C. Balfour Award for Meritorious Research Department of Cardiovascular Medicine
  12. 2013
    NIH T32 Cardiovasology Training Grant (T32HL007111) Department of Cardiovascular Medicine
  13. 2013
    Outstanding Research AwardInternal Medicine Residency, Department of Internal Medicine
  14. 2012
    Nominated by peers to represent class at Mayo Clinic Internal Medicine Residency Council Internal Medicine Residency, Department of Internal Medicine
  15. 2012
    "ACE" AwardInternal Medicine Residency, Department of Internal Medicine
  16. 2010
    Dean's Award for Outstanding Doctoral DissertationUniversity at Buffalo School of Medicine and Biomedical Sciences
  17. 2006
    American Medical Association Foundation Grant for American Physician Scientist Association Finance CommitteeAmerican Medical Association
  18. 2006
    American Heart Association Pre-Doctoral Fellowship Northeastern AffiliateAmerican Heart Association
  19. 2006
    Mark Diamond Research Fund GrantUniversity at Buffalo School of Medicine and Biomedical Sciences
  20. 2005
    Gilbert D. Moore Fellowship AwardUniversity at Buffalo School of Medicine and Biomedical Sciences
  21. 2003
    American Chemical Society Biochemistry AwardNiagara University
  22. 2003
    Niagara University Biology MedalNiagara University
  23. 2003
    Father Dana Duggan AwardNiagara University
  24. 2003
    Niagara Shares AwardNiagara University
  25. 2003
    Healthcare Association of Niagara County Incorporated (HANCI) Spirit of Niagara Student Service AwardHealth Care Association of Niagara County
  26. 2003
    The Niagara Medal-nomination Niagara University
  27. 2003
    Medical Scientist Training Program Award - 2003-2010 (Full Tuition Scholarship + Stipend) University at Buffalo School of Medicine and Biomedical Sciences
  28. 2003
    Rochester Academy of Sciences Grant Rochester Academy of Sciences

Professional memberships

  1. 2026 - present
    Member, Cardiovascular/Coagulation Task ForceMayo Clinic Pharmaceutical Formulary Subcommittee
  2. 2026 - 2027
    Member, Health Policy and Regulatory Affairs CommitteeHeart Rhythm Society
  3. 2026 - present
    Co-DirectorMayo Clinic Cardiac Electrophysiology Board Review Course
  4. 2024
    Master's Thesis Advisory Committee MemberMayo Clinic College of Medicine and Science - Fatima M. Ezzeddine - Master's Thesis
  5. 2024
    InterviewerCardiac Electrophysiology Fellowship Program Recruitment
  6. 2023 - present
    Sub-committe - MemberAmerican College of Cardiology
  7. 2023
    Master's Thesis Advisory Committee MemberMayo Clinic College of Medicine and Science - Narayan Gurukripa Kowlgi - Master's Thesis
  8. 2023 - present
    MemberMayo CV Research Committee
  9. 2023
    MemberMayo Clinic Cardiovascular CME Education Course Review Committee
  10. 2022
    Abstract ReviewerAmerican College of Cardiology
  11. 2022 - present
    Full MemberInternational Society for Electroporation-Based Technologies and Treatments (ISEBTT)
  12. 2022 - 2023
    Core Concepts for Allied Professionals - Content ReviewerHeart Rhythm Society
  13. 2022 - 2023
    Core Concepts in EP Review Course 2022 - Content ReviewerHeart Rhythm Society
  14. 2022 - present
    Professional MemberEuropean Society of Cardiology
  15. 2022 - present
    Medical EditorMayo Clinic Cardiovascular Update Newsletter
  16. 2022 - 2024
    Member - Digital Education CommitteeHeart Rhythm Society
  17. 2022 - 2025
    Member - NCDR EP Registry Research and Publications SubcommitteeAmerican College of Cardiology
  18. 2021 - 2023
    InterviewerInternal Medicine Residency Program
  19. 2021
    InterviewerMayo Clinic School of Graduate Medical Education
  20. 2021 - 2022
    Professional MemberAmerican Heart Association
  21. 2021 - present
    FellowAmerican College of Cardiology
  22. 2021 - 2022
    Core Concepts in EP 2021 - CME Content ReviewerHeart Rhythm Society
  23. 2021 - present
    Fellow of the Heart Rhythm SocietyHeart Rhythm Society
  24. 2021 - present
    Member, Core Concepts in EP for Allied Professionals Advisory GroupHeart Rhythm Society
  25. 2021 - 2022
    Education Programs and Services Subcommittee MemberHeart Rhythm Society
  26. 2021 - 2022
    Educational Subcommittee MemberHeart Rhythm Society
  27. 2021 - present
    Physician MemberHeart Rhythm Society
  28. 2020 - 2024
    InterviewerCardiology Fellowship Program Recruitment
  29. 2020 - 2021
    Communications Committee MemberHeart Rhythm Society
  30. 2020 - present
    Curriculum CommitteeHeart Rhythm Society
  31. 2020 - present
    Silver MemberEuropean Heart Rhythm Association
  32. 2020 - present
    Editorial BoardMayo Clinic Health Newsletter
  33. 2019
    Evaluation Committee MemberCardiac Electrophysiology Program
  34. 2016 - 2020
    Affiliate MemberHeart Rhythm Society
  35. 2013 - 2019
    Fellow in TrainingAmerican College of Cardiology
  36. 2010 - 2013
    Minnesota ACP Chapter Student MemberAmerican College of Physicians
  37. 2008 - 2010
    Council MemberUniversity at Buffalo School of Medicine and Biomedical Sciences MD/PhD
  38. 2007 - 2016
    Clinical Cardiology Council Student MemberAmerican Heart Association
  39. 2006 - 2016
    Student MemberAmerican Heart Association
  40. 2006 - 2013
    Student MemberAmerican College of Physicians
  41. 2006 - 2011
    Student MemberBiophysical Society
  42. 2006 - 2011
    Student MemberAmerican Medical Association
  43. 2006 - 2008
    Medical Student MemberAmerican Physiological Society
  44. 2006 - 2007
    Finance Committee MemberAmerican Physician Scientists Association
  45. 2006 - 2007
    Institutional RepresentativeAmerican Physician Scientists Association
  46. 2006 - 2007
    Basic Sciences Council Student MemberAmerican Heart Association
  47. 2006 - 2007
    PresidentPhysiology and Biophysics Graduate Student Association
  48. 2002 - 2003
    PresidentDelta Epsilon Sigma Scholastic Honor Society
  49. 2002 - 2003
    PresidentSigma Alpha Sigma
  50. 2001 - 2002
    PresidentAmerican Chemical Society

Publications

Research activities

See a description of research activities.