Mayo Clinic's approach

Your hyperbaric oxygen therapy at Mayo Clinic is based on your doctor getting to know you and understanding your health issues. Together, you'll define a comprehensive whole-person treatment plan to address your needs.

Types of conditions treated

Hyperbaric oxygen therapy is used for three main circumstances:

  • Lifesaving. Hyperbaric oxygen therapy can save the lives of people with air or gas embolisms, decompression sickness, or carbon monoxide poisoning.
  • Limb saving. It can be an effective treatment for nonhealing wounds of people at risk of losing a limb or who have had a crush injury.
  • Tissue saving. It can help repair tissue damage caused by burns, help heal muscle and skin grafts, and treat severe infections.

At Mayo Clinic, hyperbaric oxygen therapy is typically delivered in a large, rectangular chamber with up to three times the normal air pressure. While in the chamber, you receive 100% oxygen through a lightweight hood. You are assisted by a nurse.

Hyperbaric oxygen treatments usually last about 90 minutes. The chamber is equipped with an entertainment system to make your treatment relaxing. The number of treatments you receive depends on your condition. Some people may require as few as two or three sessions for conditions such as carbon monoxide poisoning or up to 40 sessions for nonhealing wounds.

The Mayo Clinic experience and patient stories

Our patients tell us that the quality of their interactions, our attention to detail and the efficiency of their visits mean health care like they've never experienced. See the stories of satisfied Mayo Clinic patients.

Expertise and rankings


Mayo Clinic's board-certified specialists in undersea and hyperbaric medicine administer thousands of treatments each year. Mayo's program is accredited by the Undersea and Hyperbaric Medical Society in conjunction with The Joint Commission.

State-of-the-art facility

Mayo Clinic has one of the largest hyperbaric oxygen therapy chambers in the United States. It accommodates several people at a time and has provided over 30,000 therapies since opening its doors in 2008.


Hyperbaric medicine doctors work with experts in many other specialties, including vascular medicine, radiation oncology and reconstructive surgical specialties. This multidisciplinary team of specialized experts collaborates on your care.


Mayo doctors and researchers share new medical advancements and treatment guidelines for hyperbaric oxygen therapy. Hyperbaric medicine is part of Mayo's Aerospace Medicine program, which has a long history of research on low-oxygen conditions in flight.

Locations, travel and lodging

Mayo Clinic has major campuses in Phoenix and Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota. The Mayo Clinic Health System has dozens of locations in several states.

For more information on visiting Mayo Clinic, choose your location below:

Costs and insurance

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people.

In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals, or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Learn more about appointments at Mayo Clinic.

Please contact your insurance company to verify medical coverage and to obtain any needed authorization prior to your visit. Often, your insurer's customer service number is printed on the back of your insurance card.

More information about billing and insurance:

Mayo Clinic in Arizona, Florida and Minnesota

Mayo Clinic Health System

Oct. 28, 2020
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  2. Mechem CC, et al. Hyperbaric oxygen therapy. Accessed Sept. 14, 2020.
  3. Moghadam N, et al. Hyperbaric oxygen therapy in sports musculoskeletal injuries. Medicine and Science in Sports and Exercise. 2019; doi:10.1249/MSS.0000000000002257.
  4. Hyperbaric oxygen therapy: Don't be misled. U.S. Food and Drug Administration. Accessed Sept. 14, 2020.
  5. Office of Patient Education. Hyperbaric oxygen therapy. Mayo Clinic; 2010.
  6. Accredited facilities. Undersea and Hyperbaric Medical Society. Accessed Sept. 14, 2020.
  7. Shields RC (expert opinion). Mayo Clinic. Sept. 25, 2020.
  8. Melnyczenko AR (expert opinion). Mayo Clinic. Sept. 25, 2020.