Departments and specialties

Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery.


Surgeons in an operating room

Mayo Clinic surgeons are actively involved in breast cancer research

Mayo Clinic breast cancer surgeons regularly participate in research activities designed to improve patient care.

Areas of research include:

  • Improving care for people with a high risk of breast cancer. Mayo Clinic researchers found nipple-sparing mastectomy to be safe for women with BRCA gene mutations undergoing prophylactic mastectomy.
  • Reducing the risk of mastectomy complications. Researchers are working to understand who faces a risk of lymphedema after surgery to remove the lymph nodes and devising ways to reduce this risk through innovative surgical techniques and neoadjuvant therapies.
  • Relieving pain after mastectomy. Pain control techniques before, during and after mastectomy are reducing the need for strong pain medications during recovery. These innovations make procedures that are more likely to cause postoperative pain, such as bilateral mastectomy and mastectomy with immediate reconstruction, more comfortable.
  • Understanding how breast cancer develops. Researchers are working to understand the conditions under which breast cancer begins to develop, including understanding the unique microorganisms present within the breast (breast microbiome). These investigations may yield data that can help prevent breast cancer or devise the most effective treatments.
  • Personalizing breast cancer treatments. Researchers are working on the latest treatments that take into account your genes and the particular genes of your cancer cells to offer personalized medicine for breast cancer. Examples include discovering new biomarkers for targeted drug therapy and engineering vaccines to prevent breast cancer recurrence.

Mayo Clinic Cancer Center is one of a handful of U.S. facilities that received a National Cancer Institute (NCI) Specialized Programs of Research Excellence (SPORE) grant for breast cancer research.


See a list of publications on breast cancer surgery by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles

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Breast cancer surgery care at Mayo Clinic

May 11, 2019
  1. AskMayoExpert. Breast cancer. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2017.
  2. AskMayoExpert. Breast reconstruction. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2017.
  3. Breast cancer. Fort Washington, Pa.: National Comprehensive Cancer Network. Accessed June 28, 2017.
  4. Townsend CM Jr, et al., eds. Diseases of the breast. Sabiston Textbook of Surgery: The Biological Basis of Modern Surgical Practice. 20th ed. Philadelphia, Pa.: Saunders Elsevier; 2017. Accessed June 28, 2017.
  5. Kwong A, et al. Mastectomy: Indications, types and concurrent axillary lymph node management. Accessed July 6, 2017.
  6. Warner KJ. Allscripts EPSi. Mayo Clinic, Rochester, Minn. April 21, 2017.
  7. McDermott AM, et al. Surgeon and breast unit volume-outcome relationships in breast cancer surgery and treatment. Annals of Surgery. 2013;258:808.
  8. Choi M, et al. Breast in a day: Examining single-stage immediate, permanent implant reconstruction in nipple-sparing mastectomy. Plastic and Reconstructive Surgery. 2016;138:184e.
  9. Richardson G, et al. The Goldilocks mastectomy. International Journal of Surgery. 2012;10:522.
  10. Hieken TJ, et al. A novel treatment schedule for rapid completion of surgery and radiation in early-stage breast cancer. Annals of Surgical Oncology. 2016;23:3297.
  11. Anderson BO, et al. Oncoplastic techniques in breast conserving therapy. Accessed July 6, 2017.
  12. Fahy AS, et al. Paravertebral blocks in patients undergoing mastectomy with or without immediate reconstruction provides improved pain control and decreased postoperative nausea and vomiting. Annals of Surgical Oncology. 2014;21:3284.
  13. Abdelsattar JM, et al. Comparative study of liposomal bupivacaine versus paravertebral block for pain control following mastectomy with immediate tissue expander reconstruction. Annals of Surgical Oncology. 2016;23:465.
  14. Drackley NL, et al. Effect of massage therapy for postsurgical mastectomy recipients. Clinical Journal of Oncology Nursing. 2012;16:121.
  15. Parks RM, et al. Axillary reverse mapping in N0 patients requiring sentinel lymph node biopsy — A systematic review of the literature and necessity of a randomized study. The Breast. 2017;33:57.
  16. Jakub J, et al. Oncologic safety of prophylactic nipple-sparing mastectomy in a population with BRCA mutations: A multi-institutional study. JAMA Surgery. In press. Accessed Sept. 18, 2017.
  17. Breast SPOREs. National Cancer Institute. Accessed July 3, 2017.
  18. National Accreditation Program for Breast Centers. American College of Surgeons. Accessed Aug. 2, 2017.
  19. Effects of anesthesia. American Society of Anesthesiologists. home/preparing for surgery/effects of anesthesia. Accessed Aug. 1, 2017.
  20. Jakub JW (expert opinion). Mayo Clinic, Rochester, Minnesota. July 31, 2017.
  21. Hieken TJ (expert opinion). Mayo Clinic, Rochester, Minnesota. Aug. 1, 2017.
  22. Searching for cancer centers. American College of Surgeons. Accessed Aug. 2, 2017.