Mayo Clinic's approach

  • Experience. It's important to choose health care providers with experience. This helps ensure that you get the results you expect. Mayo Clinic health care providers perform more than 5,000 Botox injections each year.
  • Time for you. Your Mayo Clinic specialist will take time to discuss options and answer your questions about Botox injections.
  • Efficient care. At Mayo Clinic your appointments are coordinated. So you may be able to complete your treatment in 1 to 3 days. But keep in mind that sometimes getting approval from your insurance company to cover the procedure can take several weeks.

Locations, travel and lodging

Mayo Clinic has major campuses in Phoenix and Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota. The Mayo Clinic Health System has dozens of locations in several states.

For more information on visiting Mayo Clinic, choose your location below:

Costs and insurance

Botox injections can cost several thousand dollars for each set of shots. Many insurance companies will cover the injections for certain medical conditions. Examples include chronic migraine and hyperhidrosis. Botox injections are not covered for cosmetic treatment of wrinkles.

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people.

In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals, or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Learn more about appointments at Mayo Clinic.

Please contact your insurance company to verify medical coverage and to obtain any needed authorization prior to your visit. Often, your insurer's customer service number is printed on the back of your insurance card.

Estimate your cost using Mayo Clinic's online estimator tool

More information about billing and insurance:

Mayo Clinic in Arizona, Florida and Minnesota

Mayo Clinic Health System

Clinical trials

Explore Mayo Clinic studies of tests and procedures to help prevent, detect, treat or manage conditions.

March 10, 2023
  1. Carruthers J, et al. Overview of botulinum toxin for cosmetic indications. Accessed Nov. 16, 2022.
  2. Botox cosmetic — OnabotulinumtoxinA injection, powder, lyophilized, for solution. Allergan Inc; 2021. Accessed Nov. 16, 2022.
  3. AskMayoExpert. Spasmodic dysphonia. Mayo Clinic; 2022.
  4. Avram MR, et al., eds. Injectables. In: Procedural Dermatology. McGraw Hill; 2015.
  5. Lukacz ES. Urgency urinary incontinence/overactive bladder (OAB) in females: Treatment. Accessed Nov. 16, 2022.
  6. AskMayoExpert. Cervical dystonia (spasmodic torticollis). Mayo Clinic; 2022.
  7. Ami TR. Allscripts EPSi. Mayo Clinic. Dec. 20, 2022.
  8. Garva I, et al. Chronic migraine. Accessed Nov. 17, 2022.
  9. Smith CC, et al. Primary focal hyperhidrosis. Accessed Nov. 17, 2022.
  10. AskMayoExpert. Ultrasound-guided peripheral injections. Mayo Clinic; 2021.
  11. Link JL (expert opinion). Mayo Clinic. Dec. 21, 2022.